1997
Characterization of a YAC contig containing the NBCCS locus and a novel Kruppel‐type zinc finger sequence on chromosome segment 9q22.3
Chidambaram A, Gailani M, Gerrard B, Stewart C, Goldstein A, Chumakov I, Bale A, Dean M. Characterization of a YAC contig containing the NBCCS locus and a novel Kruppel‐type zinc finger sequence on chromosome segment 9q22.3. Genes Chromosomes And Cancer 1997, 18: 212-218. PMID: 9071574, DOI: 10.1002/(sici)1098-2264(199703)18:3<212::aid-gcc7>3.0.co;2-4.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBasal Cell Nevus SyndromeBase SequenceChromosome MappingChromosomes, Artificial, YeastChromosomes, Human, Pair 9CosmidsCpG IslandsDNA-Binding ProteinsDNA, ComplementaryGene DeletionGenomic LibraryHeterozygoteHumansKruppel-Like Transcription FactorsMicrosatellite RepeatsMolecular Sequence DataPolymerase Chain ReactionRepressor ProteinsSequence Analysis, DNASequence Tagged SitesTranscription FactorsZinc FingersConceptsSomatic cell hybrid panel analysisYAC contigNew zinc finger geneZinc finger geneHuman chromosome regionYeast artificial chromosome contigInformative microsatellite lociArtificial chromosome contigZinc finger sequencesPolymorphic marker lociFinger geneMicrosatellite lociChromosome regionsMarker lociDevelopmental defectsSite mappingLinkage analysisContigsLoss of heterozygosityCytogenetic evidenceLociGenesNevoid basal cell carcinoma syndromeAutosomal dominant disorderFinger sequencesPulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: placement of a novel zinc finger gene within the NBCCS and ESS1 region
Levanat S, Chidambaram A, Wicking C, Bray-Ward P, Pressman C, Toftgard R, Gailani M, Myers J, Wainwright B, Dean M, Bale A. Pulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: placement of a novel zinc finger gene within the NBCCS and ESS1 region. Cytogenetic And Genome Research 1997, 76: 208-213. PMID: 9186526, DOI: 10.1159/000134551.Peer-Reviewed Original ResearchConceptsNovel zinc finger geneChromosome 9q22Gene-rich regionsZinc finger geneHuman disease lociGel electrophoresisFISH mappingFinger genePFGE fragmentsNotI fragmentsRestriction fragment lengthDisease locusD9S196Field gel electrophoresisD9S180FishFragment lengthGenesKbInterphase FISHPulsed-field gel electrophoresisElectrophoresisFragmentsCOL15A1Loci
1992
Assignment of a Locus for Familial Melanoma, MLM, to Chromosome 9p13-p22
Cannon-Albright L, Goldgar D, Meyer L, Lewis C, Anderson D, Fountain J, Hegi M, Wiseman R, Petty E, Bale A, Olopade O, Diaz M, Kwiatkowski D, Piepkorn M, Zone J, Skolnick M. Assignment of a Locus for Familial Melanoma, MLM, to Chromosome 9p13-p22. Science 1992, 258: 1148-1152. PMID: 1439824, DOI: 10.1126/science.1439824.Peer-Reviewed Original ResearchConceptsMelanoma susceptibility locusSusceptibility lociFamilial melanoma susceptibilityInterferon alpha genesFamilial melanomaMultipoint linkage analysisShort tandem repeat markersRepeat markersTandem repeat markersChromosomal regionsGenetic markersLinkage analysisLociSomatic lossMelanoma susceptibilityMelanoma tumorsGermline deletionChromosome 9p21Maximum location scoreHomozygous deletionCritical roleCandidate regionsDeletionUtah kindredsChromosomesRegional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19
Mitchell A, Bale A, Lee B, Hatfield D, Harley H, Rundle S, Fan Y, Fukushima Y, Shows T, McBride O. Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19. Cytogenetic And Genome Research 1992, 61: 117-120. PMID: 1395717, DOI: 10.1159/000133385.Peer-Reviewed Original Research
1991
Localization of a DNA segment encompassing four tRNA genes to human chromosome 14q11 and its use as an anchor locus for linkage analysis
Mitchell A, Bale A, Wang-ge M, Yi H, White R, Pirtle R, McBride O. Localization of a DNA segment encompassing four tRNA genes to human chromosome 14q11 and its use as an anchor locus for linkage analysis. Genomics 1991, 11: 1063-1070. PMID: 1686015, DOI: 10.1016/0888-7543(91)90033-b.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceChromosome MappingChromosomes, Human, Pair 14FemaleGenetic LinkageGenetic MarkersHumansMaleMolecular Sequence DataMultigene FamilyNucleic Acid HybridizationPolymorphism, Restriction Fragment LengthRestriction MappingRNA, TransferRNA, Transfer, LeuRNA, Transfer, ProRNA, Transfer, ThrConceptsT cell receptor alphaTRNA genesAnchor lociChromosomal locationHuman/rodent somatic cell hybridsRodent somatic cell hybridsLinkage analysisChromosome 14Human tRNA genesSomatic cell hybridsGenetic linkage analysisTRNA clusterMYH7 locusGene clusterGenomic fragmentCell hybridsCEPH pedigreesChromosome 14q11Southern analysisDNA segmentsGene locusAnonymous probesLociInformative membersSitu hybridizationA contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans
Bowcock A, Farrer L, Hebert J, Bale A, Cavalli-Sforza L. A contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans. Genomics 1991, 11: 517-529. PMID: 1685473, DOI: 10.1016/0888-7543(91)90058-m.Peer-Reviewed Original ResearchConceptsLinkage mapDistinct lociChromosome 13qExcess of recombinationMean genetic distanceGenetic distanceAlpha-satellite probeFemale recombinationAdjacent lociFamily DNAChromosomal armsDisease locusCEPH family DNAsLociChromosome 13Enzyme combinationsComplete mapAdditional markersRecombinationCentimorgansGenesFold excessDNASequenceProbe
1989
Linkage analysis of multiple endocrine neoplasia type 1 with INT2 and other markers on chromosome 11
Bale S, Bale A, Stewart K, Dachowski L, McBride O, Glaser T, Green J, Mulvihill J, Brandi M, Sakaguchi K, Aurbach G, Marx S. Linkage analysis of multiple endocrine neoplasia type 1 with INT2 and other markers on chromosome 11. Genomics 1989, 4: 320-322. PMID: 2565877, DOI: 10.1016/0888-7543(89)90336-4.Peer-Reviewed Original ResearchConceptsChromosome 11Skeletal muscle glycogen phosphorylasePolymorphic DNA (RAPD) markersMuscle glycogen phosphorylaseSingle large pedigreeDNA markersGene locusFibroblast growth factorBasic fibroblast growth factorMultiple endocrine neoplasia type 1Glycogen phosphorylaseLarge pedigreeGenesLociRecent findingsMultipoint analysisGrowth factorMEN1 geneMarkersINT2PedigreeMEN1 patientsPhosphorylaseType 1