Dual role for Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice
Belperron AA, Liu N, Booth CJ, Bockenstedt LK. Dual role for Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice. Frontiers In Cellular And Infection Microbiology 2014, 4: 75. PMID: 24967215, PMCID: PMC4052197, DOI: 10.3389/fcimb.2014.00075.Peer-Reviewed Original ResearchConceptsInnate immune cellsWild-type miceB. burgdorferi infectionB. burgdorferi-infected miceBurgdorferi-infected miceImmune cellsBurgdorferi infectionType micePathogen burdenHost defenseFc receptor common gamma chainIgG-mediated clearanceC-reactive proteinBorrelia burgdorferiToll-Like Receptor InteractionsSingle knockout miceCommon gamma chainAcute phaseInfected jointsArthritis severityMolecule MyD88Inflammatory cytokinesInflammatory pathwaysIL-1betaReactive protein