2024
2023 Society for Academic Emergency Medicine Consensus Conference on Precision Emergency Medicine: Development of a policy‐relevant, patient‐centered research agenda
Strehlow M, Gisondi M, Caretta‐Weyer H, Ankel F, Brackett A, Brar P, Chan T, Garabedian A, Gunn B, Isaacs E, von Isenburg M, Jarman A, Kuehl D, Limkakeng A, Lydston M, McGregor A, Pierce A, Raven M, Salhi R, Stave C, Tan J, Taylor R, Wong H, Yiadom M, Zachrison K, Vogel J. 2023 Society for Academic Emergency Medicine Consensus Conference on Precision Emergency Medicine: Development of a policy‐relevant, patient‐centered research agenda. Academic Emergency Medicine 2024 PMID: 38779704, DOI: 10.1111/acem.14932.Peer-Reviewed Original ResearchEmergency medicinePatient-centered research agendaData-driven health careEvidence-based research agendaDefinition of precision medicineNational consensus conferenceEducational gapConsensus-building activitiesConsensus-building processClinician trainingHealth careEMS cliniciansHealth technologiesConsensus processResearch agendaStakeholder inputResearch questionsSocioeconomic conditionsConsensus conferenceHealthPrecision medicineReview relevant literatureExpert opinionIndividual patientsMedicineExamining trends in emergency medicine journals' publications about racism
Ryus C, Yang D, Brackett A, Barnett L, Boatright D. Examining trends in emergency medicine journals' publications about racism. Academic Emergency Medicine 2024, 31: 339-345. PMID: 38097532, DOI: 10.1111/acem.14852.Peer-Reviewed Original ResearchExecutive summary of the American Radium Society appropriate use criteria for brain metastases in epidermal growth factor receptor mutated-mutated and ALK-fusion non-small cell lung cancer
Nagpal S, Milano M, Chiang V, Soltys S, Brackett A, Halasz L, Garg A, Sahgal A, Ahluwalia M, Tom M, Palmer J, Knisley J, Chao S, Gephart M, Wang T, Lo S, Chang E. Executive summary of the American Radium Society appropriate use criteria for brain metastases in epidermal growth factor receptor mutated-mutated and ALK-fusion non-small cell lung cancer. Neuro-Oncology 2024, 26: 1195-1212. PMID: 38459978, PMCID: PMC11226873, DOI: 10.1093/neuonc/noae041.Peer-Reviewed Original ResearchNon-small cell lung cancerTyrosine kinase inhibitorsCell lung cancerCentral nervous systemAmerican Radium SocietyALK-fusionBrain metastasesAmerican Radium Society Appropriate Use CriteriaLung cancerSequence of tyrosine kinase inhibitorsALK tyrosine kinase inhibitorsTreatment of brain metastasesEGFR tyrosine kinase inhibitorsWhole-brain RTEpidermal growth factor receptorGrowth factor receptorAppropriate Use CriteriaBrain RTEGFR-mutantRadiotherapyTreatment optionsFactor receptorKinase inhibitorsNervous systemLiterature searchPatient‐reported outcome measure use among older adults after emergency department care: A systematic review
Gettel C, Galske J, Sather A, Haidous A, Hwang U, Brackett A, Venkatesh A, Rising K, Goldberg E, van Oppen J, Conroy S, Carpenter C. Patient‐reported outcome measure use among older adults after emergency department care: A systematic review. Academic Emergency Medicine 2024, 31: 273-287. PMID: 38366698, DOI: 10.1111/acem.14850.Peer-Reviewed Original ResearchPatient-reported outcome measuresActivities of daily livingED visitsOlder adultsPhysical functionPatient-reported outcome measure useInstrumental activities of daily livingKatz activities of daily livingOlder adult ED patientsPatient-reported outcome measure assessmentSystematic reviewOutcome measure useEmergency department carePatient symptom burdenFull-text screeningAdult ED patientsRisk of biasQuality of lifeStudy inclusion criteriaWeb of Science-Core CollectionKatz ActivitiesEmergency careDaily livingPROM assessmentBarthel Index
2023
Emergent Applications of Machine Learning for Diagnosing and Managing Appendicitis: A State-of-the-Art Review
Bhandarkar S, Tsutsumi A, Schneider E, Ong C, Paredes L, Brackett A, Ahuja V. Emergent Applications of Machine Learning for Diagnosing and Managing Appendicitis: A State-of-the-Art Review. Surgical Infections 2023, 25: 7-18. PMID: 38150507, DOI: 10.1089/sur.2023.201.Peer-Reviewed Original ResearchArtificial intelligence toolsNew artificial intelligence toolsArtificial neural networkSupport vector machineMachine learning-based toolLearning-based toolIntelligence toolsMachine learningUse casesNeural networkVector machineRandom forestAverage accuracyNovel solutionMachineEmergent applicationsAlgorithmOptimal modelQueriesHigh operator dependencyArt reviewAccuracyToolNetworkOperator dependencySystematic review of inferior vena cava atresia
Saab K, Brahmandam A, Brackett A, Desai M, Dardik A, Guzman R, Chaar C. Systematic review of inferior vena cava atresia. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 11: 1253-1264. PMID: 37453547, DOI: 10.1016/j.jvsv.2023.07.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDeep vein thrombosisIVC atresiaCongenital anomaliesLeg painMost patientsDevelopment of DVTSystematic reviewAcceptable mid-term resultsInferior vena cava atresiaEndovascular surgical interventionsMortality of patientsOutcomes of patientsMid-term resultsRare venous anomalyTerms of patencyVein thrombosisSymptomatic reliefVenous anomaliesIliac veinInferior venaSurgical interventionMean ageTreatment groupsPatientsAtresiaRepresentation of patients with non-English language preferences in motor vehicle collision trauma and emergency medicine research
Smith M, Tibbetts C, Agrawal P, Cordone A, Leff R, Smith R, Moran T, Brackett A, Zeidan A. Representation of patients with non-English language preferences in motor vehicle collision trauma and emergency medicine research. Injury Prevention 2023, 29: 253-258. PMID: 36854627, DOI: 10.1136/ip-2022-044813.Peer-Reviewed Original ResearchConceptsNon-English language preferenceMotor vehicle collisionsRepresentation of patientsStudy inclusion/exclusion criteriaStandardised reporting toolsInclusion/exclusion criteriaDisparate health outcomesPaucity of literatureEmergency medicine researchPrimary outcomePatient populationInclusion criteriaTraumatic injuryExclusion criteriaEligible articlesHealth outcomesAppropriate interventionsLanguage preferenceCollision traumaPatientsSystematic searchEmergency medicineOutcomesVehicle collisionsFull text
2022
Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic Review
Maduka R, Tai K, Gonsai R, DeWalt N, Chetty A, Brackett A, Olino K, Schneider E, Ahuja V. Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic Review. Journal Of Surgical Research 2022, 283: 274-281. PMID: 36423476, DOI: 10.1016/j.jss.2022.10.025.Peer-Reviewed Original ResearchConceptsCutaneous melanomaSystematic reviewOutdoor occupationsGrading of RecommendationsChronic occupational exposureRetrospective case controlInternational Prospective RegisterNew cancer casesMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsInitial database searchFull-text screeningCutaneous melanoma developmentEvidence certaintyCohort studyScreening recommendationsCommon cancerRisk factorsStudy protocolProspective RegisterCase ascertainmentCancer casesOccupational exposureStudy qualityCase control120 Inclusion of Non-English Language Preference Patients in Trauma and Emergency Medicine Related Motor Vehicle Collision Research
Leff R, Agrawal P, Tibbetts C, Smith M, Cordone A, Brackett A, Moran T, Smith R, Zeidan A. 120 Inclusion of Non-English Language Preference Patients in Trauma and Emergency Medicine Related Motor Vehicle Collision Research. Annals Of Emergency Medicine 2022, 80: s57-s58. DOI: 10.1016/j.annemergmed.2022.08.144.Peer-Reviewed Original ResearchDetecting Cognitive Impairment and Dementia in the Emergency Department: A Scoping Review
Nowroozpoor A, Dussetschleger J, Perry W, Sano M, Aloysi A, Belleville M, Brackett A, Hirshon JM, Hung W, Moccia JM, Ohuabunwa U, Shah MN, Hwang U, Network G, Aggarwal N, Bellolio M, Betz M, Biese K, Brandt C, Bruursema S, Carnahan R, Carpenter C, Carr D, Chin-Hansen J, Daven M, Degesys N, Dresden S, Ellenbogen M, Falvey J, Foster B, Gettel C, Gilmore-Bykovskyi A, Goldberg E, Han J, Hardy J, Hastings S, Hogan T, Isaacs E, Jaspal N, Johnson J, Kelly K, Kennedy M, Kind A, Malone M, Moreno M, Morrow-Howell N, Oiyemhonlan B, Resendez J, Rising K, Savage B, Suyama J, Swartzberg J, Tolia V, Vann A, Webb T, Weintraub S. Detecting Cognitive Impairment and Dementia in the Emergency Department: A Scoping Review. Journal Of The American Medical Directors Association 2022, 23: 1314-1315.e55. PMID: 35940682, PMCID: PMC10804640, DOI: 10.1016/j.jamda.2022.03.019.Peer-Reviewed Original ResearchConceptsSix-Item ScreenerEmergency departmentCognitive impairmentED settingConsensus conferenceScoping ReviewHigh negative predictive valueAdult ED patientsNegative predictive valueMedical research databasesOttawa 3DYSystematic scoping reviewED patientsResearch funding prioritiesClinical careResearch DatabasePredictive valueCare partnersResearch prioritiesDementiaImpairmentConsensus processPractice gapTask ForceFuture research prioritiesEvidence of Racial Disparities in the Lung Cancer Screening Process: a Systematic Review and Meta-Analysis
Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Tanoue L, Bastian LA. Evidence of Racial Disparities in the Lung Cancer Screening Process: a Systematic Review and Meta-Analysis. Journal Of General Internal Medicine 2022, 37: 3731-3738. PMID: 35838866, PMCID: PMC9585128, DOI: 10.1007/s11606-022-07613-2.Peer-Reviewed Original ResearchConceptsLung cancer screeningLCS participationLung cancer mortalityScreening ratesWhite patientsSystematic reviewCancer mortalityPatient populationRacial disparitiesPatient studiesLung cancer screening processAllied Health Literature databasesLow-dose chestHigh-risk individualsMethodsA systematic reviewCancer screening processFull-text reviewTitles/abstractsWeb of ScienceBlack patientsDatabase inceptionCancer screeningClinical trialsInclusion criteriaProvider awarenessInterventions Targeted to Address Social Determinants of Health in Ischemic Heart Disease: A Sex- and Gender-Oriented Scoping Review
Raparelli V, Wright CX, Corica B, Sharma G, Lindley K, Brackett A, Pilote L, Wood MJ, Dreyer RP. Interventions Targeted to Address Social Determinants of Health in Ischemic Heart Disease: A Sex- and Gender-Oriented Scoping Review. Canadian Journal Of Cardiology 2022, 38: 1881-1892. PMID: 35809812, DOI: 10.1016/j.cjca.2022.06.025.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseHealth care systemHeart diseaseCare systemPatient education interventionsMajor health problemSex-stratified analysesSocial supportSDOH interventionsIHD patientsMale patientsSDOH domainsMinority patientsCare implementationHealth literacyPatientsHealth problemsRCTsSocial determinantsReporting of findingsInterventionSuch interventionsSDOHScoping ReviewSocioeconomic determinantsUnited States Emergency Department Screening for Drug Use Among Assault-Injured Individuals: A Systematic Review
Coupet E, Dodington J, Brackett A, Vaca FE. United States Emergency Department Screening for Drug Use Among Assault-Injured Individuals: A Systematic Review. Western Journal Of Emergency Medicine 2022, 23: 443-450. PMID: 35980419, PMCID: PMC9391011, DOI: 10.5811/westjem.2022.5.55475.Peer-Reviewed Original ResearchConceptsDrug useSystematic reviewNon-duplicated studiesModifiable risk factorsEmergency Department ScreeningEmergency department settingBusy emergency department settingMeta-analysis protocolMedical Subject Headings termsPreferred Reporting ItemsSubject Headings termsFull-text articlesOvid AMEDTreatment initiationCochrane CENTRALOvid EmbaseDirect referralRisk factorsDepartment settingPharmacological interventionsCommon drugsReporting ItemsTreatment servicesClinical modelScreen questionsThe Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain A Meta-Analysis
Agha AM, Pacor J, Grandhi GR, Mszar R, Khan SU, Parikh R, Agrawal T, Burt J, Blankstein R, Blaha MJ, Shaw LJ, Al-Mallah MH, Brackett A, Cainzos-Achirica M, Miller EJ, Nasir K. The Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain A Meta-Analysis. JACC Cardiovascular Imaging 2022, 15: 1745-1757. PMID: 36202453, DOI: 10.1016/j.jcmg.2022.03.031.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseAcute chest painCoronary artery calciumCoronary artery diseaseStable chest painNonobstructive coronary artery diseaseMajor adverse cardiac eventsAdverse cardiac eventsChest painCardiac eventsLow prevalenceAbsence of CACHealth care delivery modelsCare delivery modelsA Meta-AnalysisNegative predictive valueCAC assessmentArtery calciumCAC scoreIntermediate riskArtery diseaseCoronary CTACTA assessmentPrognostic valueTomography angiographyLimited English Proficiency as a Barrier to Inclusion in Emergency Medicine-Based Clinical Stroke Research
Zeidan AJ, Smith M, Leff R, Cordone A, Moran TP, Brackett A, Agrawal P. Limited English Proficiency as a Barrier to Inclusion in Emergency Medicine-Based Clinical Stroke Research. Journal Of Immigrant And Minority Health 2022, 25: 181-189. PMID: 35652977, DOI: 10.1007/s10903-022-01368-y.Peer-Reviewed Original ResearchConceptsLimited English proficiencyLEP populationsEnglish proficiencyStroke researchUse of languageExclusion criteriaInclusion/exclusion criteriaClinical stroke researchLEP patientsClinical research studiesLanguageResearch practicesSecondary outcomesPrimary outcomeRoutine careAcute careEvidence-based practiceKey termsStudy participationHealth outcomesProficiencySystematic reviewResearch studiesEmergency medicineU.S. populationSystematic Review of Venous Stent Migration to the Heart
Alameddine D, Ali S, Brackett A, Attaran R, Mojibian H, Tonnessen B, Guzman R, Chaar C. Systematic Review of Venous Stent Migration to the Heart. Journal Of Vascular Surgery 2022, 75: e234-e235. DOI: 10.1016/j.jvs.2022.03.481.Peer-Reviewed Original ResearchSystematic Review of Machine Learning Models for Differentiation of Glioma from Brain Metastasis (P14-9.006)
Jekel L, Brim W, Petersen G, Merkaj S, Subramanian H, Zeevi T, Payabvash S, Khaled B, Lin M, Cui J, Brackett A, Johnson M, Omuro A, Scheffler B, Aboian M. Systematic Review of Machine Learning Models for Differentiation of Glioma from Brain Metastasis (P14-9.006). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3376.Peer-Reviewed Original ResearchEvidence-Based Clinical Practice Guidelines for Extramammary Paget Disease
Kibbi N, Owen J, Worley B, Wang J, Harikumar V, Downing M, Aasi S, Aung P, Barker C, Bolotin D, Bordeaux J, Cartee T, Chandra S, Cho N, Choi J, Chung K, Cliby W, Dorigo O, Eisen D, Fujisawa Y, Golda N, Halfdanarson T, Iavazzo C, Jiang S, Kanitakis J, Khan A, Kim J, Kuzel T, Lawrence N, Leitao M, MacLean A, Maher I, Mittal B, Nehal K, Ozog D, Pettaway C, Ross J, Rossi A, Servaes S, Solomon M, Thomas V, Tolia M, Voelzke B, Waldman A, Wong M, Zhou Y, Arai N, Brackett A, Ibrahim S, Kang B, Poon E, Alam M. Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease. JAMA Oncology 2022, 8: 618-628. PMID: 35050310, DOI: 10.1001/jamaoncol.2021.7148.Peer-Reviewed Original ResearchConceptsExtramammary Paget's diseaseSecondary extramammary Paget's diseaseClinical practice guidelinesNonsurgical treatmentPaget's diseaseMalignant neoplasmsPractice guidelinesEvidence-based clinical practice guidelinesInvasive extramammary Paget's diseaseCarbon dioxide laser therapyClinical care recommendationsInternal malignant neoplasmsMultiple skin biopsiesDistant metastatic diseaseLymph node dissectionHigh-risk tumorsCare of adultsSuperior management approachCurative intentNode dissectionProspective registryMetastatic diseaseSentinel lymphSurgical resectionTumor characteristicsMachine Learning in Differentiating Gliomas from Primary CNS Lymphomas: A Systematic Review, Reporting Quality, and Risk of Bias Assessment
Petersen G, Shatalov J, Verma T, Brim WR, Subramanian H, Brackett A, Bahar RC, Merkaj S, Zeevi T, Staib LH, Cui J, Omuro A, Bronen RA, Malhotra A, Aboian MS. Machine Learning in Differentiating Gliomas from Primary CNS Lymphomas: A Systematic Review, Reporting Quality, and Risk of Bias Assessment. American Journal Of Neuroradiology 2022, 43: 526-533. PMID: 35361577, PMCID: PMC8993193, DOI: 10.3174/ajnr.a7473.Peer-Reviewed Original ResearchConceptsMachine learning-based methodsLearning-based methodsBalanced data setData setsVector machine modelMachine learningClassification algorithmsMachine modelMachineAlgorithmData basesPrediction modelPromising resultsPrimary CNS lymphomaPrediction model study RiskRisk of biasRadiomic featuresClassifierSetCNS lymphomaWebLearningFeaturesQualitySystematic reviewMachine Learning Applications for Differentiation of Glioma from Brain Metastasis—A Systematic Review
Jekel L, Brim WR, von Reppert M, Staib L, Petersen G, Merkaj S, Subramanian H, Zeevi T, Payabvash S, Bousabarah K, Lin M, Cui J, Brackett A, Mahajan A, Omuro A, Johnson MH, Chiang VL, Malhotra A, Scheffler B, Aboian MS. Machine Learning Applications for Differentiation of Glioma from Brain Metastasis—A Systematic Review. Cancers 2022, 14: 1369. PMID: 35326526, PMCID: PMC8946855, DOI: 10.3390/cancers14061369.Peer-Reviewed Original ResearchBrain metastasesDifferentiation of gliomasMagnetic resonance imagingEligible studiesSystematic reviewSingle-center institutionConventional magnetic resonance imagingSpecific clinical circumstancesNon-invasive differentiationQuality of reportingClinical circumstancesPoor reportingClinical practiceModel assessmentResonance imagingMetastasisStudy designGliomasTRIPOD StatementMultiple studiesExternal validationClinical translationAdherenceDifferentiationReview