2024
Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryTreatment of Acute Myocardial Infarction and Cardiogenic Shock: Outcomes of the RECOVER III Postapproval Study by Society of Cardiovascular Angiography and Interventions Shock Stage
Hanson I, Rusia A, Palomo A, Tawney A, Pow T, Dixon S, Meraj P, Sievers E, Johnson M, Wohns D, Ali O, Kapur N, Grines C, Burkhoff D, Anderson M, Lansky A, Naidu S, Basir M, O'Neill W. Treatment of Acute Myocardial Infarction and Cardiogenic Shock: Outcomes of the RECOVER III Postapproval Study by Society of Cardiovascular Angiography and Interventions Shock Stage. Journal Of The American Heart Association 2024, 13: e031803. PMID: 38293995, PMCID: PMC11056148, DOI: 10.1161/jaha.123.031803.Peer-Reviewed Original ResearchMeSH KeywordsAngiographyHeart-Assist DevicesHumansMyocardial InfarctionPercutaneous Coronary InterventionProspective StudiesShock, CardiogenicTreatment OutcomeConceptsSociety for Cardiovascular AngiographyCardiovascular AngiographyAcute myocardial infarctionIII studiesCardiogenic shockStage CPercutaneous coronary interventionMyocardial infarctionPostapproval studiesCoronary interventionImpella supportKaplan-Meier survival curve analysisSociety of Cardiovascular AngiographyThirty-day survivalResponse to therapyCohort of patientsStudy of patientsPredictors of mortalitySurvival curve analysisTreatment of acute myocardial infarctionPredictive of mortalitySeverity of shockSingle-armThirty-dayStaging system
2023
Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable-polymer coronary stent - five-year results of the TARGET All Comers randomised clinical trial.
Lansky A, Xu B, Baumbach A, Kelbæk H, van Royen N, Zheng M, Knaapen P, Slagboom T, Johnson T, Vlachojannis G, Arkenbout K, Holmvang L, Janssens L, Brugaletta S, Naber C, Schmitz T, Anderson R, Rittger H, Berti S, Barbato E, Toth G, Maillard L, Valina C, Buszman P, Thiele H, Schächinger V, Wijns W. Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable-polymer coronary stent - five-year results of the TARGET All Comers randomised clinical trial. EuroIntervention 2023, 19: e844-e855. PMID: 37860860, PMCID: PMC10687649, DOI: 10.4244/eij-d-23-00409.Peer-Reviewed Original ResearchConceptsTarget lesion failureDP-EES groupPercutaneous coronary interventionBP-SES groupBP-SESPrimary endpointDP-EESRate of TLFBiodegradable polymer sirolimus-eluting stentsST-elevation myocardial infarction (STEMI) presentationMyocardial infarction presentationSirolimus-eluting stentsFive-year resultsLong-term safetyAbluminal grooveLesion failureSecondary endpointsComers populationCoronary interventionMyocardial ischaemiaStent implantationClinical trialsTargeted therapyLandmark analysisStudy outcomesSex Differences in pLVAD-Assisted High-Risk Percutaneous Coronary Intervention Insights From the PROTECT III Study
Shah T, Abu-Much A, Batchelor W, Grines C, Baron S, Zhou Z, Li Y, Maini A, Redfors B, Hussain Y, Wollmuth J, Basir M, O'Neill W, Lansky A. Sex Differences in pLVAD-Assisted High-Risk Percutaneous Coronary Intervention Insights From the PROTECT III Study. JACC Cardiovascular Interventions 2023, 16: 1721-1729. PMID: 37409991, DOI: 10.1016/j.jcin.2023.04.036.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseFemaleHumansMaleMyocardial InfarctionPercutaneous Coronary InterventionProspective StudiesRisk FactorsStrokeTreatment OutcomeConceptsHigh-risk percutaneous coronary interventionFemale patientsIII studySex-based differencesImmediate PCISYNTAX scoreClinical outcomesMyocardial infarctionStroke/transient ischemic attackWorse renal functionAcute limb ischemiaTransient ischemic attackSex differencesPercutaneous coronary interventionAcute myocardial infarctionHigher ejection fractionCause deathCoronary complicationsIschemic attackMajor bleedingNonfemoral accessPercutaneous CoronaryPrior strokeCerebrovascular eventsVascular complications
2022
Impella Versus Intra-Aortic Balloon Pump for High-Risk PCI: A Propensity-Adjusted Large-Scale Claims Dataset Analysis
Lansky AJ, Tirziu D, Moses JW, Pietras C, Ohman EM, O'Neill WW, Ekono MM, Grines CL, Parise H. Impella Versus Intra-Aortic Balloon Pump for High-Risk PCI: A Propensity-Adjusted Large-Scale Claims Dataset Analysis. The American Journal Of Cardiology 2022, 185: 29-36. PMID: 36210212, DOI: 10.1016/j.amjcard.2022.08.032.Peer-Reviewed Original ResearchConceptsHigh-risk percutaneous coronary interventionIntra-aortic balloon pumpPercutaneous coronary interventionAcute kidney injuryCardiogenic shockMyocardial infarctionIABP supportKidney injuryBalloon pumpImproved survivalPropensity adjustmentAcute ST-elevation myocardial infarctionST-elevation myocardial infarctionIndex hospitalization lengthLess myocardial infarctionPremier Healthcare DatabaseHospital myocardial infarctionPropensity-adjusted analysisMechanical circulatory supportMechanical support devicesImpella useHospital survivalIndex hospitalizationCoronary interventionReal-world practiceDepression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience)
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.Peer-Reviewed Original ResearchMeSH KeywordsCoronary AngiographyCoronary Vessel AnomaliesCoronary VesselsDepressionFemaleHumansMyocardial InfarctionRisk FactorsStress, PsychologicalVascular DiseasesConceptsSpontaneous coronary artery dissectionPatient Health Questionnaire-9Coronary artery dissectionPSS-14 scoreArtery dissectionBaseline PHQ-9 scoreAcute myocardial infarction patientsCardiovascular risk factorsPHQ-9 scoresAcute myocardial infarctionMyocardial infarction patientsYears of agePerceived Stress Scale scoresStress Scale scoresLinear mixed-effects analysisSCAD casesVIRGO StudyQuestionnaire-9Infarction patientsMixed-effects analysisMyocardial infarctionSubgroup analysisRisk factorsRoutine screeningClinical acuityHealth status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Vessel AnomaliesCoronary VesselsFemaleHealth StatusHumansMiddle AgedMyocardial InfarctionQuality of LifeVascular DiseasesConceptsSpontaneous coronary artery dissectionAcute myocardial infarctionAMI patientsCoronary artery dissectionYoung AMI patientsHealth status outcomesHealth status instrumentsSCAD patientsArtery dissectionMyocardial infarctionStatus outcomesPatientsOutcomesHousehold incomeCollege educationInfarctionImproved outcomes in patients with severely depressed LVEF undergoing percutaneous coronary intervention with contemporary practices
O'Neill WW, Anderson M, Burkhoff D, Grines CL, Kapur NK, Lansky AJ, Mannino S, McCabe JM, Alaswad K, Daggubati R, Wohns D, Meraj PM, Pinto DS, Popma JJ, Moses JW, Schreiber TL, Ohman E. Improved outcomes in patients with severely depressed LVEF undergoing percutaneous coronary intervention with contemporary practices. American Heart Journal 2022, 248: 139-149. PMID: 35192839, DOI: 10.1016/j.ahj.2022.02.006.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseHumansMyocardial InfarctionPercutaneous Coronary InterventionProspective StudiesTreatment OutcomeConceptsPercutaneous coronary interventionHigh-risk percutaneous coronary interventionPROTECT IIProTECT IIICoronary interventionDepressed LVEFIII studyIII patientsMyocardial infarctionStroke/transient ischemic attackTransient ischemic attackCompleteness of revascularizationPrior myocardial infarctionKaplan-Meier analysisDuration of supportHospital bleedingMACCE rateProcedural hypotensionCause mortalityCerebrovascular eventsIschemic attackJeopardy scorePrior CABGSYNTAX scoreHospital discharge
2021
Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis
Navarese EP, Lansky AJ, Kereiakes DJ, Kubica J, Gurbel PA, Gorog DA, Valgimigli M, Curzen N, Kandzari DE, Bonaca MP, Brouwer M, Umińska J, Jaguszewski MJ, Raggi P, Waksman R, Leon MB, Wijns W, Andreotti F. Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis. European Heart Journal 2021, 42: 4638-4651. PMID: 34002203, PMCID: PMC8669551, DOI: 10.1093/eurheartj/ehab246.Peer-Reviewed Original ResearchMeSH KeywordsCause of DeathCoronary Artery DiseaseHumansMyocardial InfarctionMyocardial RevascularizationRandomized Controlled Trials as TopicReproducibility of ResultsConceptsSpontaneous myocardial infarctionStable coronary artery disease patientsCoronary artery disease patientsElective coronary revascularisationMedical therapyCardiac mortalityMyocardial infarctionCoronary revascularisationCause mortalityDisease patientsPre-specified primary endpointCoronary artery diseaseRate ratioDeath risk reductionRandom-effects modelMultivessel diseaseMortality findingsPrimary endpointSecondary endpointsStable patientsStroke riskSurvival benefitArtery diseaseCardiac deathRevascularisation
2016
Safety and Efficacy of Bivalirudin in Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention: From the REPLACE-2, ACUITY and HORIZONS-AMI Trials
Giustino G, Mehran R, Bansilal S, Feit F, Lincoff M, Deliargyris EN, Kirtane AJ, Généreux P, Redfors B, Prats J, Bernstein D, Brener SJ, Skerjanec S, Lansky AJ, Francese DP, Dangas GD, Stone GW. Safety and Efficacy of Bivalirudin in Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention: From the REPLACE-2, ACUITY and HORIZONS-AMI Trials. The American Journal Of Cardiology 2016, 118: 6-16. PMID: 27181566, DOI: 10.1016/j.amjcard.2016.04.005.Peer-Reviewed Original ResearchConceptsGlycoprotein IIb/IIIa inhibitorsPercutaneous coronary interventionMajor adverse cardiac eventsEfficacy of bivalirudinAdverse cardiac eventsDiabetes mellitusMajor bleedingCoronary interventionBivalirudin treatmentCause mortalityCardiac eventsNon-coronary artery bypass graft-related major bleedingPrimary efficacy end pointPrimary safety end pointUrgent Intervention Triage StrategyAcute Myocardial Infarction trialIIb/IIIa inhibitorsEnd pointHORIZONS-AMI trialPCI Linking AngiomaxComposite of deathEfficacy end pointMyocardial Infarction trialSafety end pointPatient-level dataSignificance of prior percutaneous revascularisation in patients with acute coronary syndromes: insights from the prospective PROSPECT registry.
Iñiguez A, Brener SJ, Jiménez VA, Maehara A, Mintz GS, Xu K, Weisz G, Lansky AJ, De Bruyne B, Serruys PW, Stone GW. Significance of prior percutaneous revascularisation in patients with acute coronary syndromes: insights from the prospective PROSPECT registry. EuroIntervention 2016, 11: 1468-74. PMID: 27107311, DOI: 10.4244/eijv11i13a285.Peer-Reviewed Original ResearchConceptsPrior PCIPrior percutaneous coronary interventionMajor adverse cardiac eventsACS patientsAcute coronary syndrome patientsAdverse cardiac eventsAcute coronary syndromeChronic kidney diseaseCoronary syndrome patientsHigh-risk featuresCongestive heart failureIntravascular ultrasound findingsPercutaneous coronary interventionPrior myocardial infarctionCoronary syndromeCardiac eventsCoronary interventionCardiac deathHeart failurePercutaneous revascularisationKidney diseaseMyocardial infarctionUltrasound findingsIndependent associationMultivariable modelImpact of gender on infarct size, ST-segment resolution, myocardial blush and clinical outcomes after primary stenting for acute myocardial infarction: Substudy from the EMERALD trial
Ng VG, Mori K, Costa RA, Kish M, Mehran R, Urata H, Saku K, Stone GW, Lansky AJ. Impact of gender on infarct size, ST-segment resolution, myocardial blush and clinical outcomes after primary stenting for acute myocardial infarction: Substudy from the EMERALD trial. International Journal Of Cardiology 2016, 207: 269-276. PMID: 26808991, DOI: 10.1016/j.ijcard.2016.01.013.Peer-Reviewed Original ResearchConceptsPrimary percutaneous interventionAcute myocardial infarctionST-segment resolutionInfarct sizeMyocardial infarctionST-segment elevation acute myocardial infarctionPrimary PCIPrior acute myocardial infarctionElevation acute myocardial infarctionComplete ST resolutionSmaller infarct sizeDistal protection devicesSmall vessel sizeGender-specific factorsDistal protectionEMERALD trialLAD infarctsMore hypertensionWorse comorbiditiesMidterm outcomesPrimary stentingSegment resolutionAMI patientsClinical outcomesST resolution
2015
Pretreatment with aspirin in acute coronary syndromes: Lessons from the ACUITY and HORIZONS-AMI trials
Brener SJ, Mehran R, Lansky AJ, Ayele GM, Stone GW. Pretreatment with aspirin in acute coronary syndromes: Lessons from the ACUITY and HORIZONS-AMI trials. European Heart Journal Acute Cardiovascular Care 2015, 5: 449-454. PMID: 26722003, DOI: 10.1177/2048872615624848.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAspirinFemaleHumansIncidenceMaleMiddle AgedMyocardial InfarctionConceptsAcute coronary syndromeHORIZONS-AMI trialCoronary syndromeAspirin pretreatmentMyocardial infarctionCardiac deathStent thrombosisSegment elevation acute coronary syndromesST-segment elevation myocardial infarctionElevation acute coronary syndromeAcute coronary syndrome patientsLarge randomized clinical trialsAdverse ischemic eventsTarget vessel revascularizationCoronary syndrome patientsIndependent risk factorElevation myocardial infarctionLarge prospective studiesHigh-risk cohortIncidence of deathRandomized clinical trialsMultivariable regression analysisPrior revascularizationVessel revascularizationIschemic eventsImpact of Bleeding and Bivalirudin Therapy on Mortality Risk in Women Undergoing Percutaneous Coronary Intervention (from the REPLACE-2, ACUITY, and HORIZONS-AMI Trials)
Ng VG, Baumbach A, Grinfeld L, Lincoff AM, Mehran R, Stone GW, Lansky AJ. Impact of Bleeding and Bivalirudin Therapy on Mortality Risk in Women Undergoing Percutaneous Coronary Intervention (from the REPLACE-2, ACUITY, and HORIZONS-AMI Trials). The American Journal Of Cardiology 2015, 117: 186-191. PMID: 26704028, DOI: 10.1016/j.amjcard.2015.10.029.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionStrong independent predictorMajor bleedingMortality rateBivalirudin therapyCoronary interventionIndependent predictorsFemale genderGlycoprotein IIb/IIIa inhibitor treatmentST-segment elevation myocardial infarctionNon-coronary artery bypassPatient-level pooled analysisImpact of bleedingMajor bleeding ratesPronounced clinical benefitOutcomes of patientsAcute coronary syndromeCohort of patientsElevation myocardial infarctionArtery bypassCoronary syndromeMultivariate adjustmentStandard therapyClinical benefitPooled analysisEffect of Ischemia Duration and Door-to-Balloon Time on Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction An Analysis From HORIZONS-AMI Trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction)
Prasad A, Gersh BJ, Mehran R, Brodie BR, Brener SJ, Dizon JM, Lansky AJ, Witzenbichler B, Kornowski R, Guagliumi G, Dudek D, Stone GW. Effect of Ischemia Duration and Door-to-Balloon Time on Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction An Analysis From HORIZONS-AMI Trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction). JACC Cardiovascular Interventions 2015, 8: 1966-1974. PMID: 26738667, DOI: 10.1016/j.jcin.2015.08.031.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCoronary CirculationDrug-Eluting StentsFemaleHumansMaleMetalsMicrocirculationMiddle AgedMyocardial InfarctionMyocardial Perfusion ImagingPercutaneous Coronary InterventionProspective StudiesProsthesis DesignRisk AssessmentRisk FactorsStentsTime FactorsTime-to-TreatmentTreatment OutcomeConceptsPrimary percutaneous coronary interventionMyocardial blush gradePrimary PCIHORIZONS-AMI trialMBG 0/1Balloon timeIndependent predictorsAnterior infarctionMyocardial perfusionST-segment elevation myocardial infarction (STEMI) patientsST-segment elevation myocardial infarctionHigher clinical risk profileElevation myocardial infarction patientsMyocardial Infarction (TIMI) risk scoreClinical risk profileMechanical reperfusion therapyReference vessel diameterElevation myocardial infarctionPercutaneous coronary interventionST-segment elevationEpicardial blood flowMinimum lumen diameterMyocardial infarction patientsMicrovascular reperfusionBlush gradeThe Variation in Recovery
Spatz ES, Curry LA, Masoudi FA, Zhou S, Strait KM, Gross CP, Curtis JP, Lansky AJ, Soares Barreto-Filho JA, Lampropulos JF, Bueno H, Chaudhry SI, D'Onofrio G, Safdar B, Dreyer RP, Murugiah K, Spertus JA, Krumholz HM. The Variation in Recovery. Circulation 2015, 132: 1710-1718. PMID: 26350057, PMCID: PMC4858327, DOI: 10.1161/circulationaha.115.016502.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetAlgorithmsAortic DissectionClassificationCoronary DiseaseDiagnostic Techniques, CardiovascularFemaleHumansMaleMedical RecordsMiddle AgedMyocardial InfarctionMyocardiumOxygen ConsumptionPhenotypePlaque, AtheroscleroticProspective StudiesReproducibility of ResultsRisk FactorsSex FactorsTreatment OutcomeYoung AdultConceptsAcute myocardial infarctionCoronary artery diseaseArtery diseaseClinical phenotypeNonobstructive coronary artery diseaseYoung AMI Patients (VIRGO) studyObstructive coronary artery diseaseYoung womenType 2 acute myocardial infarctionBiological disease mechanismsSubset of patientsThird universal definitionUnique clinical phenotypeCulprit lesionClinical characteristicsMyocardial infarctionTherapeutic efficacyUniversal definitionStudy participantsPatientsSupply-demand mismatchYoung adultsDisease mechanismsPatient studiesCurrent classification schemesMorphological changes and clinical impact of unstable plaques within untreated segments of acute myocardial infarction patients during a 3-year follow-up
Souza CF, Doi H, Mintz GS, Lansky AJ, Witzenbichler B, Guagliumi G, Brodie BR, Kellett MA, Xu K, Mehran R, Stone GW, Maehara A. Morphological changes and clinical impact of unstable plaques within untreated segments of acute myocardial infarction patients during a 3-year follow-up. Coronary Artery Disease 2015, 26: 469-475. PMID: 25919902, DOI: 10.1097/mca.0000000000000251.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery DiseaseCoronary VesselsFemaleHumansMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPlaque, AtheroscleroticPlatelet Aggregation InhibitorsPredictive Value of TestsProspective StudiesRisk FactorsRupture, SpontaneousStentsTime FactorsTreatment OutcomeUltrasonography, InterventionalWound HealingConceptsST-segment elevation myocardial infarctionPlaque ruptureIntravascular ultrasoundClinical eventsUnstable plaquesLumen compromiseUntreated segmentsAcute Myocardial Infarction trialLong-term clinical outcomesAcute myocardial infarction patientsBaseline intravascular ultrasoundOptimal systemic therapySerial IVUS analysisMyocardial Infarction trialElevation myocardial infarctionInfarct-related arteryMyocardial infarction patientsThree-year followAttenuated plaqueHarmonizing OutcomesNonculprit lesionsSTEMI patientsSystemic therapyClinical outcomesInfarction patientsWill this trial change my practice? TOTAL: a randomised trial of thrombus aspiration in ST-elevation myocardial infarction.
Behan MW, Haude M, Oldroyd KG, Lansky AJ, James S, Baumbach A. Will this trial change my practice? TOTAL: a randomised trial of thrombus aspiration in ST-elevation myocardial infarction. EuroIntervention 2015, 11: 361-3. PMID: 26196756, DOI: 10.4244/eijv11i3a70.Peer-Reviewed Original ResearchPrognostic impact of multivessel versus culprit vessel only percutaneous intervention for patients with multivessel coronary artery disease presenting with acute coronary syndrome.
Hassanin A, Brener SJ, Lansky AJ, Xu K, Stone GW. Prognostic impact of multivessel versus culprit vessel only percutaneous intervention for patients with multivessel coronary artery disease presenting with acute coronary syndrome. EuroIntervention 2015, 11: 293-300. PMID: 25136882, DOI: 10.4244/eijy14m08_05.Peer-Reviewed Original ResearchConceptsMV-percutaneous coronary interventionMajor adverse cardiac eventsPercutaneous coronary interventionAcute coronary syndromeIschaemia-driven revascularisationMyocardial infarctionNSTE-ACSCoronary syndromeMV diseaseOne-year major adverse cardiac eventsPeriprocedural non-Q-wave myocardial infarctionSegment elevation acute coronary syndromesNon-Q-wave myocardial infarctionDeath/myocardial infarctionElevation acute coronary syndromeMultivessel coronary artery diseaseUrgent Intervention Triage StrategyMultivessel percutaneous coronary interventionMV-PCI groupAdverse cardiac eventsAcute renal failureCoronary artery diseaseOne-year ratesClear clinical benefitPropensity score adjustmentSafety and efficacy of a novel abluminal groove‐filled biodegradable polymer sirolimus‐eluting stent for the treatment of de novo coronary lesions: Two‐year results from a prospective patient‐level pooled analysis of TARGET trials
Gao Z, Zhang R, Xu B, Yang Y, Ma C, Li H, Chen S, Han Y, Yuan Z, Lansky AJ, Guan C, Leon MB, Gao R, Investigators F. Safety and efficacy of a novel abluminal groove‐filled biodegradable polymer sirolimus‐eluting stent for the treatment of de novo coronary lesions: Two‐year results from a prospective patient‐level pooled analysis of TARGET trials. Catheterization And Cardiovascular Interventions 2015, 85: 734-743. PMID: 25678281, DOI: 10.1002/ccd.25861.Peer-Reviewed Original ResearchMeSH KeywordsAbsorbable ImplantsAgedCardiovascular AgentsChinaCoronary Artery DiseaseDrug-Eluting StentsFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPolymersProspective StudiesProsthesis DesignRandomized Controlled Trials as TopicRegistriesRisk FactorsSirolimusTime FactorsTreatment OutcomeConceptsTarget lesion failureFIREHAWK stentStent thrombosisCoronary lesionsMyocardial infarctionNovel abluminal groove-filled biodegradable polymer sirolimus-eluting stentDe novo native coronary lesionsBiodegradable polymer sirolimus-eluting stentsDe novo coronary lesionsPatient-level pooled analysisTarget vessel myocardial infarctionNew drug-eluting stentsNative coronary lesionsNovo coronary lesionsProbable stent thrombosisTarget lesion revascularizationVessel myocardial infarctionSirolimus-eluting stentsPatient-level analysisPatient-level dataLong-term safetyDrug-eluting stentsTwo-year resultsObjective performance criteriaLesion revascularization