2023
Prospective, randomized, multicenter clinical study comparing a self-expanding covered stent to percutaneous transluminal angioplasty for treatment of upper extremity hemodialysis arteriovenous fistula stenosis
Dolmatch B, Cabrera T, Pergola P, Balamuthusamy S, Makris A, Cooper R, Moore E, Licht J, Macaulay E, Maleux G, Pfammatter T, Settlage R, Cristea E, Lansky A, Investigators A, Dolmatch B, Goh G, Hawkins S, Macaulay E, Spark I, de Graff R, Deutschmann H, Kickuth R, Maleux G, Pfammatter T, Kirksey L, Mendes R, Aruny J, Ali V, Cabrera T, Pergola P, Sharma D, Moore E, Shah H, Dwyer A, Yee D, Teng W, Cooper R, Balamuthusamy S, Lipkowitz G, Saad T, Licht J, Makris A, Rogers T, Burgess J, Hoggard J. Prospective, randomized, multicenter clinical study comparing a self-expanding covered stent to percutaneous transluminal angioplasty for treatment of upper extremity hemodialysis arteriovenous fistula stenosis. Kidney International 2023, 104: 189-200. PMID: 36990214, DOI: 10.1016/j.kint.2023.03.015.Peer-Reviewed Original ResearchConceptsTarget lesion primary patencyAccess circuit primary patencyPercutaneous transluminal angioplastyTarget lesion reinterventionPrimary patencyTransluminal angioplastyArteriovenous fistulaAVF stenosisAdditional clinical outcomesCircuit primary patencyCovered stent groupLesion primary patencyMulticenter clinical studyHemodialysis arteriovenous fistula stenosisArteriovenous fistula stenosisHemodialysis patientsPrimary outcomeRandomized studyClinical outcomesAVF dysfunctionStent groupClinical studiesFistula stenosisSix monthsPatients
2022
Randomized Trial of Chocolate Touch Compared With Lutonix Drug-Coated Balloon in Femoropopliteal Lesions (Chocolate Touch Study)
Shishehbor MH, Zeller T, Werner M, Brodmann M, Parise H, Holden A, Lichtenberg M, Parikh SA, Kashyap VS, Pietras C, Tirziu D, Ardakani S, Beschorner U, Krishnan P, Niazi KA, Wali AU, Lansky AJ. Randomized Trial of Chocolate Touch Compared With Lutonix Drug-Coated Balloon in Femoropopliteal Lesions (Chocolate Touch Study). Circulation 2022, 145: 1645-1654. PMID: 35377157, DOI: 10.1161/circulationaha.122.059646.Peer-Reviewed Original ResearchConceptsLutonix drug-coated balloonDrug-coated balloonsEnd pointPrimary efficacy end pointPrimary safety end pointIndependent clinical events committeeIschemic rest painPrimary efficacy rateEfficacy end pointPrimary end pointSafety end pointClinical events committeeMajor adverse eventsRate of restenosisDrug-Coated BalloonNoninferiority end pointSafety event rateAverage lesion lengthMajor amputationPopliteal diseaseRest painBailout stentingEfficacy ratePrimary patencyAdverse events
2020
Clinical outcome after interventions with paclitaxel-coated balloons: a PCR statement.
Lansky A, Cremonesi A, Scheller B, James S, Grubman D, Fajadet J, Sauguet A, Micari A, Sarno G, Bosiers M, Baumbach A, Wijns W. Clinical outcome after interventions with paclitaxel-coated balloons: a PCR statement. EuroIntervention 2020, 15: 1225-1227. PMID: 32044731, DOI: 10.4244/eijv15i14a220.Peer-Reviewed Original Research
2019
Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study
Gray WA, Cardenas JA, Brodmann M, Werner M, Bernardo NI, George JC, Lansky A. Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study. JACC Cardiovascular Interventions 2019, 12: 2375-2384. PMID: 31806218, DOI: 10.1016/j.jcin.2019.08.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEuropeFemaleFemoral ArteryHumansMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProspective StudiesProsthesis DesignRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesVascular Access DevicesVascular PatencyVascular System InjuriesConceptsProximal popliteal arteryDrug-coated balloonsSuperficial femoral arteryPlain balloonPopliteal arteryFemoral arteryTack Endovascular SystemLong-term outcomesDCB angioplastyEfficacy endpointPrimary patencyResidual stenosisRestenotic lesionsMulticenter studyFemoropopliteal arteriesEndovascular SystemAngioplastyArteryClassification 2DissectionLesionsBalloonStenosisPatencyPatientsBalloon-Expandable Vascular Covered Stent in the Treatment of Iliac Artery Occlusive Disease: 9-Month Results from the BOLSTER Multicenter Study
Laird JR, Zeller T, Holden A, Scheinert D, Moore E, Mendes R, Schmiedel R, Settlage R, Lansky A, Jaff MR, Investigators B, Elmasri F, Robinson W, Beasley R, Mego D, Marica S, Bersin R, Kujath S, Razavi M, Teßarek J, Schulte K. Balloon-Expandable Vascular Covered Stent in the Treatment of Iliac Artery Occlusive Disease: 9-Month Results from the BOLSTER Multicenter Study. Journal Of Vascular And Interventional Radiology 2019, 30: 836-844.e1. PMID: 30956077, DOI: 10.1016/j.jvir.2018.12.031.Peer-Reviewed Original ResearchConceptsMajor adverse eventsWalking Impairment QuestionnaireQuality of lifeLesion revascularizationPrimary patencyMyocardial infarctionIliac artery occlusive diseaseComposite endpoint rateProcedure-related deathsTarget lesion revascularizationArtery occlusive diseaseSingle-arm studyMajor amputationRutherford categoryOcclusive lesionsPrimary endpointSecondary endpointsAdverse eventsClinical improvementImpairment QuestionnaireOcclusive diseaseClinical outcomesMulticenter studyEndpoint rateIliac artery
2018
A prospective, multi‐center study of the chocolate balloon in femoropopliteal peripheral artery disease: The Chocolate BAR registry
Mustapha JA, Lansky A, Shishehbor M, McClure J, Johnson S, Davis T, Makam P, Crowder W, Konstantino E, Attaran RR, Investigators T. A prospective, multi‐center study of the chocolate balloon in femoropopliteal peripheral artery disease: The Chocolate BAR registry. Catheterization And Cardiovascular Interventions 2018, 91: 1144-1148. PMID: 29513389, DOI: 10.1002/ccd.27565.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonEquipment DesignFemaleFemoral ArteryHumansMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProduct Surveillance, PostmarketingProspective StudiesRegistriesRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesVascular Access DevicesVascular PatencyConceptsTarget lesion revascularizationPrimary endpointFemoropopliteal peripheral artery diseaseSymptomatic peripheral arterial diseaseExcellent procedural outcomesLower dissection ratePeripheral arterial diseasePeripheral artery diseaseAcute procedural successLong-term outcomesPost-market registryMulti-center studyAngioplasty balloon catheterPercutaneous transluminal angioplasty balloon catheterRutherford classCause mortalityLesion revascularizationMajor amputationArtery diseaseArterial diseaseProcedural successUnplanned amputationBalloon catheterProcedural outcomesProcedure success
2015
Local delivery of paclitaxel in the treatment of peripheral arterial disease
Ng VG, Mena C, Pietras C, Lansky AJ. Local delivery of paclitaxel in the treatment of peripheral arterial disease. European Journal Of Clinical Investigation 2015, 45: 333-345. PMID: 25615282, DOI: 10.1111/eci.12407.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseEndovascular revascularizationArtery diseaseLocal deliveryClinical studiesLocal drug deliveryPeripheral arterial diseasePeripheral vascular diseasePrimary patency rateSystemic adverse effectsUse of paclitaxelLong-term efficacyDrug-Eluting BalloonDrug-eluting stentsTerms of efficacyBrief exposure periodArterial diseaseBalloon angioplastyPatency ratesVascular diseaseBalloon catheterCoated balloonMEDLINE searchStent failureActive drug
2012
Nitinol Stent Implantation vs. Balloon Angioplasty for Lesions in the Superficial Femoral and Proximal Popliteal Arteries of Patients With Claudication: Three-Year Follow-up From the RESILIENT Randomized Trial
Laird JR, Katzen BT, Scheinert D, Lammer J, Carpenter J, Buchbinder M, Dave R, Ansel G, Lansky A, Cristea E, Collins TJ, Goldstein J, Cao AY, Jaff MR. Nitinol Stent Implantation vs. Balloon Angioplasty for Lesions in the Superficial Femoral and Proximal Popliteal Arteries of Patients With Claudication: Three-Year Follow-up From the RESILIENT Randomized Trial. Journal Of Endovascular Therapy 2012, 19: 1-9. PMID: 22313193, DOI: 10.1583/11-3627.1.Peer-Reviewed Original ResearchMeSH KeywordsAgedAlloysAngioplasty, BalloonArterial Occlusive DiseasesChi-Square DistributionConstriction, PathologicEuropeFemaleFemoral ArteryHumansIntermittent ClaudicationKaplan-Meier EstimateMaleMiddle AgedPopliteal ArteryPredictive Value of TestsProsthesis DesignRadiographyRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeUltrasonography, Doppler, DuplexUnited StatesVascular PatencyConceptsTarget lesion revascularizationBalloon angioplastyAngioplasty groupStent groupProximal popliteal artery lesionsGood long-term resultsNitinol stent implantationProximal popliteal arteryMajor adverse eventsLong-term resultsPopliteal artery lesionsShort-term patencyStent fracture rateThree-year followLesion revascularizationPrimary nitinolWithdrew consentIntermittent claudicationAdverse eventsArtery lesionsFemoropopliteal lesionsMulticenter trialPopliteal arteryPrimary implantationSuperficial femoral
2010
Nitinol Stent Implantation Versus Balloon Angioplasty for Lesions in the Superficial Femoral Artery and Proximal Popliteal Artery
Laird JR, Katzen BT, Scheinert D, Lammer J, Carpenter J, Buchbinder M, Dave R, Ansel G, Lansky A, Cristea E, Collins TJ, Goldstein J, Jaff MR. Nitinol Stent Implantation Versus Balloon Angioplasty for Lesions in the Superficial Femoral Artery and Proximal Popliteal Artery. Circulation Cardiovascular Interventions 2010, 3: 267-276. PMID: 20484101, DOI: 10.1161/circinterventions.109.903468.Peer-Reviewed Original ResearchConceptsSuperficial femoral arteryProximal popliteal arteryTarget lesion revascularizationAngioplasty groupStent groupFemoral arteryLesion revascularizationPopliteal arteryBalloon angioplastyPrimary patencyAngiographic resultsBetter acute angiographic resultsProvisional stent implantationSuboptimal angiographic resultsEndovascular treatment strategiesFlow-limiting dissectionPercutaneous transluminal angioplastyAcute angiographic resultsTotal lesion lengthLoss of patencySuperficial femoral artery (SFA) stentingSelf-expanding nitinolBailout stentingIntermittent claudicationPrimary stenting
2006
Drug-Eluting and Bare Nitinol Stents for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: Long-Term Results from the SIROCCO Trial
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, Mudde C, Tielemans H, Beregi JP. Drug-Eluting and Bare Nitinol Stents for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: Long-Term Results from the SIROCCO Trial. Journal Of Endovascular Therapy 2006, 13: 701-710. PMID: 17154704, DOI: 10.1583/05-1704.1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlloysAngioplasty, BalloonAnti-Bacterial AgentsAtherosclerosisBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleDouble-Blind MethodDrug CarriersFemaleFemoral ArteryHumansKaplan-Meier EstimateMaleMiddle AgedProspective StudiesProsthesis FailureRecurrenceSafetySirolimusStentsTreatment OutcomeConceptsChronic limb ischemiaAnkle-brachial indexBare stent groupRestenosis rateSirolimus groupLimb ischemiaStent groupSuperficial femoral artery occlusionType C lesionsDouble-blinded studySymptoms of claudicationBare nitinol stentsMajority of patientsSuperficial femoral arteryFemoral artery occlusionStent restenosis rateNitinol self-expanding stentsSelf-expanding stentsTypes of stentsTVR ratesTLR rateArtery occlusionC lesionsClinical outcomesDrug-Eluting
2003
Acute and long-term outcomes of cutting balloon angioplasty followed by gamma brachytherapy for in-stent restenosis
Kobayashi Y, Mehran R, Mintz GS, Dangas G, Moussa I, Collins M, Brara P, Moussavian M, Lansky AJ, Stone GW, Leon MB, Moses JW, Teirstein PS. Acute and long-term outcomes of cutting balloon angioplasty followed by gamma brachytherapy for in-stent restenosis. The American Journal Of Cardiology 2003, 92: 1329-1331. PMID: 14636914, DOI: 10.1016/j.amjcard.2003.08.018.Peer-Reviewed Original ResearchComparison of in-hospital and one-year outcomes after multiple coronary arterial stenting in patients ≥80 years old versus those <80 years old
Kobayashi Y, Mehran R, Mintz GS, Dangas G, Moussa I, Lansky AJ, Stone GW, Moses JW, Leon MB. Comparison of in-hospital and one-year outcomes after multiple coronary arterial stenting in patients ≥80 years old versus those <80 years old. The American Journal Of Cardiology 2003, 92: 443-446. PMID: 12914876, DOI: 10.1016/s0002-9149(03)00663-5.Peer-Reviewed Original ResearchConceptsHigh technical success rateCoronary arterial stentingOne-year outcomesTechnical success rateHigh mortality rateComplication rateMultivessel stentingArterial stentingHospital cardiacMortality rateYounger counterpartsSuccess rateStentingPatientsHospitalPresent studyOutcomesYearsMultivesselOctogenariansCardiac
2001
Intravascular Radiation Therapy after Balloon Angioplasty of Narrowed Femoropopliteal Arteries to Prevent Restenosis: Results of the PARIS Feasibility Clinical Trial
Waksman R, Laird J, Jurkovitz C, Lansky A, Gerrits F, Kosinski A, Murrah N, Weintraub W, Investigators F. Intravascular Radiation Therapy after Balloon Angioplasty of Narrowed Femoropopliteal Arteries to Prevent Restenosis: Results of the PARIS Feasibility Clinical Trial. Journal Of Vascular And Interventional Radiology 2001, 12: 915-921. PMID: 11487671, DOI: 10.1016/s1051-0443(07)61569-3.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal angioplastyAnkle-brachial indexRadiation therapySFA lesionsRestenosis rateBalloon angioplastyAngiographic binary restenosis rateMean reference vessel diameterSuccessful percutaneous transluminal angioplastySuperficial femoral artery lesionsClinical restenosis rateFeasibility clinical trialBinary restenosis rateClinical adverse eventsReference vessel diameterFemoral artery lesionsMean lesion lengthRate gamma radiationIntravascular radiation therapyMicroSelectron-HDR afterloaderGamma radiation therapyRutherford scoreAdverse eventsArtery lesionsClinical improvementAre we making progress with percutaneous saphenous vein graft treatment? A comparison of 1990 to 1994 and 1995 to 1998 results
Hong M, Mehran R, Dangas G, Mintz G, Lansky A, Kent K, Pichard A, Satler L, Stone G, Leon M. Are we making progress with percutaneous saphenous vein graft treatment? A comparison of 1990 to 1994 and 1995 to 1998 results. Journal Of The American College Of Cardiology 2001, 38: 150-154. PMID: 11451265, DOI: 10.1016/s0735-1097(01)01324-9.Peer-Reviewed Original ResearchConceptsLate cardiac eventsSVG lesionsCardiac eventsDistal embolizationStent useSaphenous vein graft angioplastyUnfavorable lesion characteristicsVein graft angioplastyOne-year outcomesProcedural success rateHigh procedural successHigh-risk lesionsGraft angioplastySVG angioplastyLate mortalityRepeat revascularizationBaseline characteristicsProcedural successRisk lesionsFavorable outcomeLesion characteristicsGraft treatmentMultivariate analysisAngioplastyLesions
2000
Intracoronary γ-Radiation Therapy After Angioplasty Inhibits Recurrence in Patients With In-Stent Restenosis
Waksman R, White R, Chan R, Bass B, Geirlach L, Mintz G, Satler L, Mehran R, Serruys P, Lansky A, Fitzgerald P, Bhargava B, Kent K, Pichard A, Leon M. Intracoronary γ-Radiation Therapy After Angioplasty Inhibits Recurrence in Patients With In-Stent Restenosis. Circulation 2000, 101: 2165-2171. PMID: 10801757, DOI: 10.1161/01.cir.101.18.2165.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonCoronary DiseaseDouble-Blind MethodFemaleGamma RaysHumansMaleMiddle AgedRecurrenceStentsTreatment OutcomeConceptsStent restenosisIntracoronary gamma radiation therapyLess target lesion revascularizationBinary angiographic restenosisSuccessful coronary interventionTarget lesion revascularizationMajor cardiac eventsIndependent core laboratoryIntracoronary stent implantationInitial clinical trialsGamma radiation therapyLesion revascularizationAngiographic restenosisVessel revascularizationAngiographic outcomesCardiac eventsClinical restenosisCoronary interventionAdjunct therapyProcedural successStent implantationClinical trialsTreatment protocolNeointimal formationRadiation groupAtherosclerotic Plaque Burden and CK-MB Enzyme Elevation After Coronary Interventions
Mehran R, Dangas G, Mintz G, Lansky A, Pichard A, Satler L, Kent K, Stone G, Leon M. Atherosclerotic Plaque Burden and CK-MB Enzyme Elevation After Coronary Interventions. Circulation 2000, 101: 604-610. PMID: 10673251, DOI: 10.1161/01.cir.101.6.604.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonCoronary Artery DiseaseCreatine KinaseFemaleHumansIsoenzymesMaleMiddle AgedUltrasonography, InterventionalConceptsCK-MB elevationAtherosclerotic plaque burdenPreintervention intravascular ultrasoundPlaque burdenTimes upper limitIntravascular ultrasoundCoronary interventionSerum creatine kinase MB fractionPlatelet glycoprotein IIb/IIIa inhibitorsGlycoprotein IIb/IIIa inhibitorsReference segmentsFinal minimal lumen diameterLesion site plaque burdenIIb/IIIa inhibitorsCreatine kinase MB fractionAngiographic lesion morphologyDe novo lesionsNative coronary lesionsPercutaneous coronary interventionMinimal lumen diameterDiffuse atherosclerotic diseaseCatheter-based interventionsCross-sectional narrowingAtheroablative techniquesLate mortality
1999
Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention
Dangas G, Mintz G, Mehran R, Lansky A, Kornowski R, Pichard A, Satler L, Kent K, Stone G, Leon M. Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention. Circulation 1999, 99: 3149-3154. PMID: 10377078, DOI: 10.1161/01.cir.99.24.3149.Peer-Reviewed Original ResearchConceptsIndependent predictorsArterial remodelingTarget lesion revascularization rateInsulin-dependent diabetic patientsLong-term clinical outcomesQ-wave myocardial infarctionMultivariable logistic regression analysisTarget lesion revascularizationShort-term complicationsIntravascular ultrasound studyLong-term outcomesFinal lumen areaLogistic regression analysisIntermediate remodelingAngiographic characteristicsAngiographic successRevascularization ratesCoronary interventionClinical outcomesDiabetic patientsPlaque burdenPositive remodelingMyocardial infarctionNegative remodelingPercutaneous intervention