2024
Right Ventricular Dysfunction in Patients Undergoing High-Risk PCI with Impella
Rommel K, Bonnet G, Bellumkonda L, Lansky A, Zhao D, Thompson J, Zhang Y, Redfors B, Lurz P, Granada J, Bharadwaj A, Basir M, O'Neill W, Burkhoff D. Right Ventricular Dysfunction in Patients Undergoing High-Risk PCI with Impella. Journal Of Cardiac Failure 2024, 30: 1244-1254. PMID: 39389734, DOI: 10.1016/j.cardfail.2024.08.001.Peer-Reviewed Original ResearchConceptsRight ventricular dysfunctionHigh-risk percutaneous coronary interventionVentricular dysfunctionAssociated with right ventricular dysfunctionTricuspid annular plane systolic excursionConcomitant right ventricular dysfunctionLower left ventricular ejection fractionUnfavorable long-term prognosisAnnular plane systolic excursionClinical outcomes of patientsAbsence of right ventricular dysfunctionImpella supportPredictor of 1-year mortalityMultivariate Cox regression analysisIncidence of hypotensive episodesEchocardiography core laboratorySevere RV dilatationBlood urea nitrogen levelsRV function assessmentVentricular ejection fractionOutcomes of patientsRates of in-hospital mortalityHigher blood urea nitrogen levelsLong-term prognosisProportion of patientsTreatment of Acute Myocardial Infarction and Cardiogenic Shock: Outcomes of the RECOVER III Postapproval Study by Society of Cardiovascular Angiography and Interventions Shock Stage
Hanson I, Rusia A, Palomo A, Tawney A, Pow T, Dixon S, Meraj P, Sievers E, Johnson M, Wohns D, Ali O, Kapur N, Grines C, Burkhoff D, Anderson M, Lansky A, Naidu S, Basir M, O'Neill W. Treatment of Acute Myocardial Infarction and Cardiogenic Shock: Outcomes of the RECOVER III Postapproval Study by Society of Cardiovascular Angiography and Interventions Shock Stage. Journal Of The American Heart Association 2024, 13: e031803. PMID: 38293995, PMCID: PMC11056148, DOI: 10.1161/jaha.123.031803.Peer-Reviewed Original ResearchMeSH KeywordsAngiographyHeart-Assist DevicesHumansMyocardial InfarctionPercutaneous Coronary InterventionProspective StudiesShock, CardiogenicTreatment OutcomeConceptsSociety for Cardiovascular AngiographyCardiovascular AngiographyAcute myocardial infarctionIII studiesCardiogenic shockStage CPercutaneous coronary interventionMyocardial infarctionPostapproval studiesCoronary interventionImpella supportKaplan-Meier survival curve analysisSociety of Cardiovascular AngiographyThirty-day survivalResponse to therapyCohort of patientsStudy of patientsPredictors of mortalitySurvival curve analysisTreatment of acute myocardial infarctionPredictive of mortalitySeverity of shockSingle-armThirty-dayStaging system
2022
Impella Versus Intra-Aortic Balloon Pump for High-Risk PCI: A Propensity-Adjusted Large-Scale Claims Dataset Analysis
Lansky AJ, Tirziu D, Moses JW, Pietras C, Ohman EM, O'Neill WW, Ekono MM, Grines CL, Parise H. Impella Versus Intra-Aortic Balloon Pump for High-Risk PCI: A Propensity-Adjusted Large-Scale Claims Dataset Analysis. The American Journal Of Cardiology 2022, 185: 29-36. PMID: 36210212, DOI: 10.1016/j.amjcard.2022.08.032.Peer-Reviewed Original ResearchConceptsHigh-risk percutaneous coronary interventionIntra-aortic balloon pumpPercutaneous coronary interventionAcute kidney injuryCardiogenic shockMyocardial infarctionIABP supportKidney injuryBalloon pumpImproved survivalPropensity adjustmentAcute ST-elevation myocardial infarctionST-elevation myocardial infarctionIndex hospitalization lengthLess myocardial infarctionPremier Healthcare DatabaseHospital myocardial infarctionPropensity-adjusted analysisMechanical circulatory supportMechanical support devicesImpella useHospital survivalIndex hospitalizationCoronary interventionReal-world practice
2021
Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention
O'Neill BP, Grines C, Moses JW, Ohman EM, Lansky A, Popma J, Kapur NK, Schreiber T, Mannino S, O'Neill WW, Medjamia AM, Mahmud E. Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention. Catheterization And Cardiovascular Interventions 2021, 98: e501-e512. PMID: 34051033, DOI: 10.1002/ccd.29758.Peer-Reviewed Original ResearchConceptsPercutaneous ventricular assist deviceNonemergent percutaneous coronary interventionPercutaneous coronary interventionHemodynamic collapseVentricular assist deviceCoronary interventionProphylactic supportImpella percutaneous ventricular assist deviceAssist deviceOutcomes of patientsVentricular ejection fractionHospital mortalityHospital outcomesEjection fractionHeart failureMedian baselinePVAD supportProphylactic strategiesFemale genderStudy populationLow prevalencePatientsMain diseaseOutcomesMortality
2020
Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race
Kim Y, Park J, Essa M, Lansky AJ, Sugeng L. Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race. The American Journal Of Cardiology 2020, 125: 1782-1787. PMID: 32471549, DOI: 10.1016/j.amjcard.2020.03.025.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMechanical circulatory supportCardiogenic shockNational Inpatient SampleHospital mortalityBlack patientsInpatient SampleMCS devicesPopulation-based retrospective cohort studyMCS utilizationMechanical circulatory support devicesOnly black patientsRetrospective cohort studyClinical Modification codesMultivariate logistic regressionCirculatory support devicesAcute clinical scenariosHospital outcomesCohort studyPrimary outcomeClinical outcomesHospital eventsCirculatory supportNinth RevisionMyocardial infarction
2019
Use of Impella heart pump for management of women with peripartum cardiogenic shock
Elkayam U, Schäfer A, Chieffo A, Lansky A, Hall S, Arany Z, Grines C. Use of Impella heart pump for management of women with peripartum cardiogenic shock. Clinical Cardiology 2019, 42: 974-981. PMID: 31436333, PMCID: PMC6788473, DOI: 10.1002/clc.23249.Peer-Reviewed Original ResearchConceptsLeft ventricular assist deviceMechanical circulatory supportCardiogenic shockPeripartum cardiomyopathyImpella deviceCatheter-based ventricular assist device registryVeno-arterial extracorporeal membrane oxygenationDurable left ventricular assist devicePercutaneous mechanical circulatory supportInotropes/vasopressorsSevere LV dysfunctionUse of ImpellaSevere heart failureManagement of womenMean ejection fractionExtracorporeal membrane oxygenationNative heart functionVentricular assist deviceHannover Medical SchoolLV dysfunctionEjection fractionHeart failureMembrane oxygenationCirculatory supportMean age
2010
When Is Door-to-Balloon Time Critical? Analysis From the HORIZONS-AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) and CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trials
Brodie BR, Gersh BJ, Stuckey T, Witzenbichler B, Guagliumi G, Peruga JZ, Dudek D, Grines CL, Cox D, Parise H, Prasad A, Lansky AJ, Mehran R, Stone GW. When Is Door-to-Balloon Time Critical? Analysis From the HORIZONS-AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) and CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trials. Journal Of The American College Of Cardiology 2010, 56: 407-413. PMID: 20650362, DOI: 10.1016/j.jacc.2010.04.020.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionLower mortality rateHigh-risk patientsPercutaneous coronary interventionMortality rateEarly presentationCoronary interventionClinical riskST-segment elevation myocardial infarctionSimilar relative risk reductionsHORIZONS-AMI trialElevation myocardial infarctionRelative risk reductionNon-percutaneous coronary intervention hospitalsMortality rate reductionImpact of doorCADILLAC trialHORIZONS-AMIAntithrombotic therapyReperfusion therapyBalloon timeIntervention hospitalsAbsolute benefitLate presentationMyocardial infarction