2013
Plaque shift and distal embolism in patients with acute myocardial infarction
Wu X, Maehara A, He Y, Xu K, Oviedo C, Witzenbichler B, Lansky AJ, Dressler O, Parise H, Stone GW, Mintz GS. Plaque shift and distal embolism in patients with acute myocardial infarction. Catheterization And Cardiovascular Interventions 2013, 82: 203-209. PMID: 22936619, DOI: 10.1002/ccd.24644.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary ThrombosisCoronary VesselsCreatine Kinase, MB FormEmbolismFemaleHumansLinear ModelsMaleMiddle AgedMyocardial InfarctionNo-Reflow PhenomenonPercutaneous Coronary InterventionPlaque, AtheroscleroticPredictive Value of TestsProsthesis DesignRandomized Controlled Trials as TopicRetrospective StudiesStentsTreatment OutcomeUltrasonography, InterventionalConceptsThrombus groupCK-MBAngiographic thrombusPlaque shiftReference segmentsAxial plaque redistributionDistal plaque embolizationDistal reference segmentsHORIZONS-AMI trialNative coronary lesionsM volumeAcute myocardial infarctionVolumetric intravascular ultrasoundBare metal stentsOverall plaque volumePeriprocedural elevationPlaque redistributionDistal embolismCoronary lesionsPlaque embolizationMyocardial infarctionStent implantationPlaque volumeInfarction lesionsIntravascular ultrasound
2010
Periprocedural Myocardial Infarction
Lansky AJ, Stone GW. Periprocedural Myocardial Infarction. Circulation Cardiovascular Interventions 2010, 3: 602-610. PMID: 21156928, DOI: 10.1161/circinterventions.110.959080.Peer-Reviewed Original ResearchEvaluation of the effects of everolimus‐eluting and paclitaxel‐eluting stents on target lesions with jailed side branches: 2‐year results from the SPIRIT III randomized trial
Applegate R, Hermiller J, Williams J, Gordon P, Doostzadeh J, Cao S, Su X, Sudhir K, Lansky A, Simonton C, Stone G. Evaluation of the effects of everolimus‐eluting and paclitaxel‐eluting stents on target lesions with jailed side branches: 2‐year results from the SPIRIT III randomized trial. Catheterization And Cardiovascular Interventions 2010, 76: 644-651. PMID: 20506356, DOI: 10.1002/ccd.22606.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBiomarkersCardiovascular AgentsCoronary AngiographyCoronary Artery DiseaseCreatine Kinase, MB FormDrug-Eluting StentsEverolimusFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionMyocardiumNecrosisPaclitaxelProspective StudiesProsthesis DesignRisk AssessmentRisk FactorsSeverity of Illness IndexSingle-Blind MethodSirolimusTime FactorsTreatment OutcomeUnited StatesConceptsPaclitaxel-eluting stentsMajor adverse cardiac eventsTwo-year clinical outcomesTAXUS paclitaxel-eluting stentSPIRIT III trialXience V EESAdverse cardiac eventsMyocardial infarction rateUpper normal levelCreatine kinase-MBSide branchesLower ratesThinner stent strutsPeriprocedural increasePeriprocedural myonecrosisPES patientsEES groupIII trialsInfarction rateCardiac eventsSide branch compromiseCardiac deathPES groupClinical outcomesAdverse outcomes
2009
Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: a risk model from the ACUITY trial
Mehran R, Pocock SJ, Stone GW, Clayton TC, Dangas GD, Feit F, Manoukian SV, Nikolsky E, Lansky AJ, Kirtane A, White HD, Colombo A, Ware JH, Moses JW, Ohman EM. Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: a risk model from the ACUITY trial. European Heart Journal 2009, 30: 1457-1466. PMID: 19351691, PMCID: PMC2695951, DOI: 10.1093/eurheartj/ehp110.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeMajor bleedingMyocardial infarctionBaseline predictorsMortality riskMajor bleedsCoronary syndromeHigh-risk acute coronary syndromesUrgent Intervention Triage Strategy (ACUITY) trialElevation acute coronary syndromeMultivariable Cox regression modelsDays of randomizationTime-updated covariatesRecurrent myocardial infarctionIndependent baseline predictorsCox regression modelShort-term riskTiming of mortalityACUITY trialAcute CatheterizationHazard ratioStrategy trialBleedingMortality hazardCox model
2005
Creatine kinase-MB enzyme elevation and long-term clinical events after successful coronary stenting in lesions with ruptured plaque
Fujii K, Carlier SG, Mintz GS, Kobayashi Y, Jacoboff D, Nierenberg H, Takebayashi H, Yasuda T, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Leon MB, Moses JW. Creatine kinase-MB enzyme elevation and long-term clinical events after successful coronary stenting in lesions with ruptured plaque. The American Journal Of Cardiology 2005, 95: 355-359. PMID: 15670544, DOI: 10.1016/j.amjcard.2004.09.033.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceCase-Control StudiesChi-Square DistributionCineangiographyCoronary AngiographyCoronary Artery DiseaseCreatine KinaseCreatine Kinase, MB FormFemaleHumansImage Processing, Computer-AssistedIsoenzymesMaleMiddle AgedRuptureStatistics, NonparametricStentsUltrasonography, InterventionalConceptsAcute coronary syndromeCoronary syndromeCoronary stentingClinical outcomesStent implantationRuptured plaquesCreatine kinase-MB isoenzyme releaseCreatine kinase‐MB enzyme elevationLong-term clinical eventsCK-MB elevationCK-MB releaseSuccessful coronary stentingControl patientsUnstable anginaEnzyme elevationIndependent predictorsProcedural complicationsClinical eventsPlaque ruptureIntravascular ultrasoundPatientsLong-term eventsPlaquesComposite rateSyndrome
2003
Increased CK-MB release is a “trade-off” for optimal stent implantation an intravascular ultrasound study
Iakovou I, Mintz GS, Dangas G, Abizaid A, Mehran R, Kobayashi Y, Lansky AJ, Aymong ED, Nikolsky E, Stone GW, Moses JW, Leon MB. Increased CK-MB release is a “trade-off” for optimal stent implantation an intravascular ultrasound study. Journal Of The American College Of Cardiology 2003, 42: 1900-1905. PMID: 14662249, DOI: 10.1016/j.jacc.2003.06.012.Peer-Reviewed Original ResearchConceptsCK-MB releaseTarget lesion revascularizationOptimal stent implantationStent expansionLesion revascularizationClinical restenosisStent implantationGroup 1Creatine kinase-MB isoenzyme releaseGroup 3Lower mortalityIntravascular ultrasound-guided stentingLower target lesion revascularizationPeak CK-MB valuesMajor adverse cardiac eventsLumen cross-sectional areaAdverse cardiac eventsAggressive stent expansionPercutaneous coronary interventionIntravascular ultrasound studyCK-MB valuesLate mortalityCardiac eventsCoronary interventionConsecutive patients
2002
Postprocedure creatine kinase-MB elevation and baseline left ventricular dysfunction predict one-year mortality after percutaneous coronary intervention
Dangas G, Mehran R, Feldman D, Stoyioglou A, Pichard AD, Kent KM, Satler LF, Fahy M, Lansky AJ, Stone GW, Leon MB. Postprocedure creatine kinase-MB elevation and baseline left ventricular dysfunction predict one-year mortality after percutaneous coronary intervention. The American Journal Of Cardiology 2002, 89: 586-589. PMID: 11867045, DOI: 10.1016/s0002-9149(01)02299-8.Peer-Reviewed Original Research
2001
Differential Impact on Survival of Electrocardiographic Q-Wave Versus Enzymatic Myocardial Infarction After Percutaneous Intervention
Stone G, Mehran R, Dangas G, Lansky A, Kornowski R, Leon M. Differential Impact on Survival of Electrocardiographic Q-Wave Versus Enzymatic Myocardial Infarction After Percutaneous Intervention. Circulation 2001, 104: 642-647. PMID: 11489768, DOI: 10.1161/hc3101.093902.Peer-Reviewed Original ResearchConceptsQ-wave myocardial infarctionMyocardial infarctionPercutaneous interventionCPK-MB elevationNon-Q-wave myocardial infarctionElective percutaneous interventionIndependent research nurseSerial creatine phosphokinasePeriprocedural myocardial infarctionTertiary referral centerRelative prognostic importanceNew Q wavesCPK-MB levelsPowerful independent determinantCPK-MB releaseEnzymatic elevationPeriprocedural infarctionReferral centerConsecutive patientsReferral populationResearch nursesIndependent determinantsPrognostic importanceStent useQ waves