2010
Serial Intravascular Ultrasound Analysis of the Impact of Myocardial Bridge on Neointimal Proliferation After Coronary Stenting in Patients with Acute Myocardial Infarction
TSUJITA K, MAEHARA A, MINTZ GS, LANSKY AJ, KUBO T, DOI H, YANG J, BHARAJ H, WITZENBICHLER B, GUAGLIUMI G, BRODIE BR, KELLETT MA, PARISE H, MEHRAN R, STONE GW. Serial Intravascular Ultrasound Analysis of the Impact of Myocardial Bridge on Neointimal Proliferation After Coronary Stenting in Patients with Acute Myocardial Infarction. Journal Of Interventional Cardiology 2010, 23: 114-122. PMID: 20236216, DOI: 10.1111/j.1540-8183.2010.00531.x.Peer-Reviewed Original ResearchConceptsCulprit lesionIntimal hyperplasiaIntravascular ultrasoundStent groupMyocardial bridgeLAD stentAcute Myocardial Infarction trialLumen areaSerial intravascular ultrasound analysisMyocardial Infarction trialAcute myocardial infarctionStent recoilSerial intravascular ultrasoundIncidence of ISRIntravascular ultrasound analysisMinimum lumen areaHarmonizing OutcomesCoronary stentingMyocardial infarctionNeointimal proliferationStent restenosisUltrasound analysisStent segmentMb segmentPatients
2007
Percutaneous Coronary Revascularization Using a Trilayer Metal Phosphorylcholine-Coated Zotarolimus-Eluting Stent
Abizaid A, Lansky AJ, Fitzgerald PJ, Tanajura LF, Feres F, Staico R, Mattos L, Abizaid A, Chaves A, Centemero M, Sousa AG, Sousa JE, Zaugg MJ, Schwartz LB. Percutaneous Coronary Revascularization Using a Trilayer Metal Phosphorylcholine-Coated Zotarolimus-Eluting Stent. The American Journal Of Cardiology 2007, 99: 1403-1408. PMID: 17493469, DOI: 10.1016/j.amjcard.2006.12.064.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBlood Vessel Prosthesis ImplantationCardiovascular AgentsCoronary AngiographyCoronary CirculationCoronary RestenosisCoronary StenosisFemaleFollow-Up StudiesHumansMaleMiddle AgedPhosphorylcholineProspective StudiesProsthesis DesignResearch DesignSirolimusStentsTreatment OutcomeTunica IntimaUltrasonography, InterventionalConceptsCoronary artery stenosisQuantitative coronary angiographyZoMaxx stentCoronary angiographyArtery stenosisDe novo coronary artery stenosisSingle-arm prospective clinical trialDevice-deployment success ratesMajor adverse cardiac eventsSegment late lumen lossCoronary occlusive diseaseIntravascular ultrasound resultsNeointimal volume obstructionAdverse cardiac eventsIndependent core laboratoryLate lumen lossNative coronary arteriesPercutaneous coronary revascularizationProspective clinical trialsCoronary stent systemReduction of restenosisCoronary revascularizationVolume obstructionCardiac eventsObstructive lesions
2006
Volumetric Intravascular Ultrasound Assessment of Neointimal Hyperplasia and Nonuniform Stent Strut Distribution in Sirolimus-Eluting Stent Restenosis
Sano K, Mintz GS, Carlier SG, Fujii K, Takebayashi H, Kimura M, Costa JR, Tanaka K, Costa RA, Lui J, Weisz G, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Volumetric Intravascular Ultrasound Assessment of Neointimal Hyperplasia and Nonuniform Stent Strut Distribution in Sirolimus-Eluting Stent Restenosis. The American Journal Of Cardiology 2006, 98: 1559-1562. PMID: 17145209, DOI: 10.1016/j.amjcard.2006.07.030.Peer-Reviewed Original ResearchConceptsMinimum lumen siteStent restenotic lesionsStent areaDiabetes mellitusLumen areaRestenotic lesionsStent strut distributionIH areaMinimal lumen area siteSirolimus-eluting stent implantationVolumetric intravascular ultrasound analysisIntravascular ultrasound assessmentMinimum stent areaIntravascular ultrasound analysisMinimum lumen areaMinimal lumen areaMinimal lumen siteIH responseSES implantationStent implantationUltrasound assessmentStent lengthNeointimal hyperplasiaStent restenosisStrut distribution
2004
Nonuniform Strut Distribution Correlates With More Neointimal Hyperplasia After Sirolimus-Eluting Stent Implantation
Takebayashi H, Mintz GS, Carlier S, Kobayashi Y, Fujii K, Yasuda T, Costa RA, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps E, Collins MB, Colombo A, Stone GW, Leon MB, Moses JW. Nonuniform Strut Distribution Correlates With More Neointimal Hyperplasia After Sirolimus-Eluting Stent Implantation. Circulation 2004, 110: 3430-3434. PMID: 15557367, DOI: 10.1161/01.cir.0000148371.53174.05.Peer-Reviewed Original ResearchConceptsMinimum lumen siteIntimal hyperplasiaLumen areaStent implantationStent strutsIH areaSmaller minimal lumen areaSirolimus-eluting stent implantationAmount of neointimaMinimum lumen areaMinimal lumen areaIVUS predictorsRestenosis patientsSES implantationRestenosis lesionsStent cellsStent strut distributionNeointimal hyperplasiaStrut distributionIntravascular ultrasoundMultivariate analysisVisible strutsComparison groupCross-sectional areaHyperplasiaSix- and Twelve-Month Results From First Human Experience Using Everolimus-Eluting Stents With Bioabsorbable Polymer
Grube E, Sonoda S, Ikeno F, Honda Y, Kar S, Chan C, Gerckens U, Lansky AJ, Fitzgerald PJ. Six- and Twelve-Month Results From First Human Experience Using Everolimus-Eluting Stents With Bioabsorbable Polymer. Circulation 2004, 109: 2168-2171. PMID: 15123533, DOI: 10.1161/01.cir.0000128850.84227.fd.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnticoagulantsCatheterizationCineangiographyCoated Materials, BiocompatibleComorbidityCoronary AngiographyCoronary RestenosisCoronary StenosisDrug ImplantsEverolimusFemaleFollow-Up StudiesGrowth InhibitorsHumansHyperplasiaImmunosuppressive AgentsLactic AcidMaleMiddle AgedMyocardial InfarctionPolyestersPolymersProspective StudiesSingle-Blind MethodSirolimusStainless SteelStentsTreatment OutcomeTunica IntimaUltrasonography, InterventionalConceptsEverolimus-eluting stentsBare metal stentsRestenosis rateMajor adverse cardiac event ratesAdverse cardiac event ratesDe novo coronary lesionsMajor adverse cardiac eventsPercent neointimal volumeSegment restenosis rateAdverse cardiac eventsCardiac event rateNovo coronary lesionsStent restenosis rateTwelve-month resultsFirst human experienceIntravascular ultrasound analysisInitial clinical experienceLate stent malappositionLate stent thrombosisStent neointimal hyperplasiaSignificant reductionRestenosis reductionCardiac eventsI trialCoronary lesions
2003
Feasibility and efficacy of tandem positioning on angiographic and clinical outcomes in the Intimal Hyperplasia Inhibition With Beta In-Stent Trial
Shirai K, Lansky AJ, Mintz GS, Costantini CO, Cristea E, Fahy M, Vandertie L, Yeung A, Raizner AE, Waksman R, Leon MB. Feasibility and efficacy of tandem positioning on angiographic and clinical outcomes in the Intimal Hyperplasia Inhibition With Beta In-Stent Trial. The American Journal Of Cardiology 2003, 91: 1113-1115. PMID: 12714158, DOI: 10.1016/s0002-9149(03)00160-7.Peer-Reviewed Original Research
2002
7-Hexanoyltaxol–Eluting Stent for Prevention of Neointimal Growth
Kataoka T, Grube E, Honda Y, Morino Y, Hur SH, Bonneau HN, Colombo A, Di Mario C, Guagliumi G, Hauptmann KE, Pitney MR, Lansky AJ, Stertzer SH, Yock PG, Fitzgerald PJ. 7-Hexanoyltaxol–Eluting Stent for Prevention of Neointimal Growth. Circulation 2002, 106: 1788-1793. PMID: 12356631, DOI: 10.1161/01.cir.0000031734.11420.1c.Peer-Reviewed Original ResearchConceptsBare metal stentsNeointimal growthIntravascular ultrasoundDe novo coronary lesionsAdjacent reference segmentsNovo coronary lesionsIndependent core laboratoryHuman feasibility studyNeointimal tissue growthIVUS substudyUnhealed dissectionConventional mechanical treatmentMulticenter trialCoronary lesionsRestenosis rateAtherosclerotic diseaseIntracoronary brachytherapyIVUS analysisNeointimal responseLong-term benefitsNeointimal thickeningStented segmentsCore laboratoryMetal stentsReference segments
2000
Experimental evaluation of a short transitional edge protection balloon for intracoronary stent deployment
Carter A, Lee D, Suzuki T, Bailey L, Lansky A, Jones R, Virmani R. Experimental evaluation of a short transitional edge protection balloon for intracoronary stent deployment. Catheterization And Cardiovascular Interventions 2000, 51: 112-119. PMID: 10973033, DOI: 10.1002/1522-726x(200009)51:1<112::aid-ccd26>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsProtection balloonArterial traumaNoncompliant balloonCoronary arteryNeointimal areaNeointimal formationStent deploymentArterial segmentsChronic vascular responsesHigh-pressure deploymentStent implantation techniqueArterial wall injuryIntracoronary stent deploymentQuantitative coronary angiographyVessel injury scoreStent neointimal hyperplasiaAdjacent arterial wallStent neointimal formationArterial injuryCoronary angiographyIntracoronary stentingEdge dissectionBalloon injuryBalloon-expandable stainless steel stentsInjury scoreIntracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis
Waksman R, Bhargava B, White L, Chan R, Mehran R, Lansky A, Mintz G, Satler L, Pichard A, Leon M, Kent K. Intracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis. Circulation 2000, 101: 1895-1898. PMID: 10779453, DOI: 10.1161/01.cir.101.16.1895.Peer-Reviewed Original ResearchConceptsRevascularization ratesBinary angiographic restenosis rateIntracoronary gamma radiation therapyTarget vessel revascularization rateTarget lesion revascularization ratePercutaneous transluminal coronary angioplastyVessel revascularization rateAngiographic restenosis rateLesion revascularization rateTransluminal coronary angioplastyIn-Stent RestenosisGamma radiation therapyRecurrent ISRPlacebo groupClinical restenosisAdjunct therapyConsecutive patientsCoronary angioplastyRestenosis rateRotational atherectomyStent implantationBalloon catheterNative coronariesStent restenosisPatients
1999
Quantitative angiographic analysis of stent restenosis in the scripps coronary radiation to inhibit intimal proliferation post stenting (SCRIPPS) trial
Lansky A, Popma J, Massullo V, Jani S, Russo R, Schatz R, Steuterman S, Guarneri E, Wu H, Mehran R, Mintz G, Leon M, Teirstein P. Quantitative angiographic analysis of stent restenosis in the scripps coronary radiation to inhibit intimal proliferation post stenting (SCRIPPS) trial. The American Journal Of Cardiology 1999, 84: 410-414. PMID: 10468078, DOI: 10.1016/s0002-9149(99)00325-2.Peer-Reviewed Original ResearchConceptsStent marginsStenting TrialStent restenosisIr-192Quantitative angiographic resultsQuantitative angiographic analysisLower restenosis ratePercent diameter stenosisLower relative riskPlacebo sourcesAngiographic resultsRestenosis rateDiameter stenosisAngiographic analysisRelative riskRestenosisTreatment lengthIridium-192Successful interventionsTrialsFurther studiesPatientsTreatmentStenosisFollow