2011
5-Year Follow-Up of Polytetrafluoroethylene-Covered Stents Compared With Bare-Metal Stents in Aortocoronary Saphenous Vein Grafts The Randomized BARRICADE (Barrier Approach to Restenosis: Restrict Intima to Curtail Adverse Events) Trial
Stone GW, Goldberg S, O'Shaughnessy C, Midei M, Siegel RM, Cristea E, Dangas G, Lansky AJ, Mehran R. 5-Year Follow-Up of Polytetrafluoroethylene-Covered Stents Compared With Bare-Metal Stents in Aortocoronary Saphenous Vein Grafts The Randomized BARRICADE (Barrier Approach to Restenosis: Restrict Intima to Curtail Adverse Events) Trial. JACC Cardiovascular Interventions 2011, 4: 300-309. PMID: 21435608, DOI: 10.1016/j.jcin.2010.11.013.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryChi-Square DistributionCoated Materials, BiocompatibleCoronary AngiographyCoronary Artery BypassCoronary RestenosisFemaleGraft Occlusion, VascularHumansKaplan-Meier EstimateMaleMetalsMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPolytetrafluoroethyleneProspective StudiesProsthesis DesignRisk AssessmentRisk FactorsSaphenous VeinStentsThrombosisTime FactorsTreatment OutcomeUnited StatesConceptsSaphenous vein graftsBare metal stentsPercutaneous coronary interventionDiseased saphenous vein graftsHigh-pressure implantationDual antiplatelet therapyTarget vessel failureAntiplatelet therapyMajor secondary end pointEnd pointPrimary end pointSecondary end pointsLong-term prognosisBinary restenosisBMS patientsCoronary interventionVein graftsVessel failureInferior outcomesSaphenous veinDiscrete lesionsPatientsPrior trialsJostentLesions
2007
Short- and Long-Term Outcomes After Stent-Assisted Percutaneous Treatment of Saphenous Vein Grafts in the Drug-Eluting Stent Era
Pucelikova T, Mehran R, Kirtane AJ, Kim YH, Fahy M, Weisz G, Lansky AJ, Moussa I, Gray WA, Collins MB, Kodali SK, Stone GW, Moses JW, Leon MB, Dangas G. Short- and Long-Term Outcomes After Stent-Assisted Percutaneous Treatment of Saphenous Vein Grafts in the Drug-Eluting Stent Era. The American Journal Of Cardiology 2007, 101: 63-68. PMID: 18157967, DOI: 10.1016/j.amjcard.2007.07.048.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary Artery BypassFemaleFollow-Up StudiesGraft Occlusion, VascularHumansMaleMultivariate AnalysisMyocardial InfarctionMyocardiumNecrosisPaclitaxelProspective StudiesProsthesis DesignRegistriesRetreatmentSaphenous VeinSirolimusStentsThrombosisConceptsMajor adverse cardiac eventsAdverse cardiac eventsPercutaneous coronary interventionDrug-eluting stentsSVG lesionsVessel revascularizationCardiac eventsCoronary interventionPercutaneous treatmentMyocardial infarctionStent-assisted percutaneous coronary interventionSaphenous vein graft lesionsNative vessel diseasePeriprocedural myocardial necrosisTarget lesion revascularizationTarget vessel revascularizationSaphenous vein graftsVein graft lesionsPresence of thrombusEmbolic protection devicesHigh-risk subgroupsLong-term outcomesContemporary clinical practiceLesion revascularizationStent thrombosesProspective, Multicenter Study of Thrombectomy in Patients with Acute Myocardial Infarction: The X‐Tract AMI Registry
YOUNG JJ, COX DA, STUCKEY T, BABB J, TURCO M, LANSKY AJ, MEHRAN R, STONE GW. Prospective, Multicenter Study of Thrombectomy in Patients with Acute Myocardial Infarction: The X‐Tract AMI Registry. Journal Of Interventional Cardiology 2007, 20: 44-50. PMID: 17300402, DOI: 10.1111/j.1540-8183.2007.00223.x.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryCanadaCardiac CatheterizationCoronary ThrombosisCoronary VesselsFemaleGraft Occlusion, VascularHumansMaleMiddle AgedMyocardial InfarctionMyocardial ReperfusionPostoperative ComplicationsProspective StudiesRegistriesSaphenous VeinSeverity of Illness IndexStentsThrombectomyTreatment OutcomeUnited StatesConceptsSaphenous vein graftsAcute myocardial infarctionNative coronary arteriesPrimary angioplastyCoronary arteryAMI registryMulticenter studyMyocardial infarctionGlycoprotein IIb/IIIa inhibitorsMyocardial blush grade 3IIb/IIIa inhibitorsDiseased saphenous vein graftsTIMI 0/1 flowMajor cardiovascular eventsTIMI 3 flowMajority of patientsEpicardial blood flowBare metal stentsCardiovascular eventsThrombectomy systemDistal embolizationMulticenter experienceThromboembolic complicationsVein graftsMyocardial blush
2004
Relation of final lumen dimensions in saphenous vein grafts after stent implantation to outcome
Iakovou I, Dangas G, Mintz GS, Mehran R, Kobayashi Y, Aymong E, Hirose M, Ashby DT, Lansky AJ, Stone GW, Leon MB, Moses JW. Relation of final lumen dimensions in saphenous vein grafts after stent implantation to outcome. The American Journal Of Cardiology 2004, 93: 963-968. PMID: 15081436, DOI: 10.1016/j.amjcard.2003.12.049.Peer-Reviewed Original ResearchConceptsSaphenous vein graftsAggressive stent expansionSVG lesionsStent expansionVein graftsMyocardial infarctionStent implantationHospital non-Q-wave myocardial infarctionLumen dimensionsGroup IINon-Q-wave myocardial infarctionIntravascular ultrasound-guided stentingTarget vessel revascularization rateVessel revascularization rateBaseline patient characteristicsMyocardial infarction rateNative coronary lesionsStent cross-sectional areaTarget vessel revascularizationPercutaneous coronary interventionNative coronary arteriesCross-sectional areaLower restenosis rateRevascularization ratesVessel revascularization1155-78 Implications and prevention of large periprocedural myocardial infarction after percutaneous intervention of diseased saphenous vein grafts and thrombotic native coronary lesions
Lasic Z, Mehran R, Nikolsky E, Negoita M, Costa R, Cox D, Babb J, Nukta D, Bilodeau L, Cannon L, Stuckey T, Hermiller J, Lansky A, Leon M, Stone G. 1155-78 Implications and prevention of large periprocedural myocardial infarction after percutaneous intervention of diseased saphenous vein grafts and thrombotic native coronary lesions. Journal Of The American College Of Cardiology 2004, 43: a88. DOI: 10.1016/s0735-1097(04)90367-1.Peer-Reviewed Original Research830-5 The impact of myocardial blush grade on clinical outcomes of patients treated with saphenous vein grafts and thrombotic native coronary arteries: Analysis from the X-TRACT trial
Tsuchiya Y, Lansky A, Costa R, Mehran R, Negoita M, Cristea E, Marginean H, Corral M, Tarawali M, Babb J, Cox D, Stone G. 830-5 The impact of myocardial blush grade on clinical outcomes of patients treated with saphenous vein grafts and thrombotic native coronary arteries: Analysis from the X-TRACT trial. Journal Of The American College Of Cardiology 2004, 43: a72. DOI: 10.1016/s0735-1097(04)90300-2.Peer-Reviewed Original Research
2003
Prospective, randomized evaluation of thrombectomy prior to percutaneous intervention in diseased saphenous vein grafts and thrombus-containing coronary arteries
Stone GW, Cox DA, Babb J, Nukta D, Bilodeau L, Cannon L, Stuckey TD, Hermiller J, Cohen EA, Low R, Bailey SR, Lansky AJ, Kuntz RE, Investigators F. Prospective, randomized evaluation of thrombectomy prior to percutaneous intervention in diseased saphenous vein grafts and thrombus-containing coronary arteries. Journal Of The American College Of Cardiology 2003, 42: 2007-2013. PMID: 14662267, DOI: 10.1016/j.jacc.2003.10.001.Peer-Reviewed Original ResearchConceptsDiseased saphenous vein graftsSaphenous vein graftsNative coronary arteriesPeri-procedural myocardial infarctionEvent-free survivalCoronary arteryMyocardial infarctionControl patientsStent implantationRoutine thrombectomyVein graftsSize patientsLate event-free survivalMajor adverse cardiac eventsPeri-procedural myonecrosisAdverse cardiac eventsHigh-risk patientsPercutaneous coronary interventionLarge myocardial infarctionSafety of interventionsPrior thrombectomyCardiac eventsCoronary interventionPercutaneous interventionLate outcomesSafety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study
Stone GW, Cox DA, Low R, Cates CU, Satler L, Bailey SR, Kuntz RE, Lansky AJ. Safety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study. Catheterization And Cardiovascular Interventions 2003, 58: 419-427. PMID: 12652487, DOI: 10.1002/ccd.10511.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAtherectomy, CoronaryChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary ThrombosisEquipment DesignEquipment SafetyFemaleFollow-Up StudiesGraft Occlusion, VascularHumansMaleMiddle AgedProbabilityRisk AssessmentSaphenous VeinStatistics, NonparametricStentsThrombectomyTreatment OutcomeConceptsSaphenous vein graftsNative coronary arteriesVein graftsX-SizerThrombotic lesionsCoronary arteryNon-Q-wave MIDistal branch occlusionTIMI 3 flowSide branch occlusionTreatment of thrombusDistal thromboemboliPeriprocedural MITIMI 0Adverse eventsThromboembolic complicationsConsecutive patientsAntegrade flowBranch occlusionPercutaneous interventionHistorical controlsAtherosclerotic lesionsTrial studyU.S. CentersLesionsThe radiance P-32 RDX balloon in saphenous vein grafts: A comparison of De-Novo and In-Stent restenotic lesions in the SVG brite trial
Costantini C, Lansky A, Shirai K, Cristea E, Marginean H, Ispas C, Proctor B, Tarawali M, Midei M, Buchbinder M, Mehran R, Dangas G, Moses J, Leon M, Stone G. The radiance P-32 RDX balloon in saphenous vein grafts: A comparison of De-Novo and In-Stent restenotic lesions in the SVG brite trial. Journal Of The American College Of Cardiology 2003, 41: 70. DOI: 10.1016/s0735-1097(03)80915-4.Peer-Reviewed Original ResearchA prospective, randomized trial of thromboatherectomy during intervention of thrombotic native coronary arteries and saphenous vein grafts: The X-TRACT trial
Stone G, Cox D, Babb J, Nukta D, Bilodeau L, Cannon L, Stuckey T, Hermiller J, Cohen E, Low R, Lansky A, Bailey S, Kuntz R. A prospective, randomized trial of thromboatherectomy during intervention of thrombotic native coronary arteries and saphenous vein grafts: The X-TRACT trial. Journal Of The American College Of Cardiology 2003, 41: 43. DOI: 10.1016/s0735-1097(03)80184-5.Peer-Reviewed Original Research
2002
Results of the Jostent coronary stent graft implantation in various clinical settings: Procedural and follow‐up results
Gercken U, Lansky AJ, Buellesfeld L, Desai K, Badereldin M, Mueller R, Selbach G, Leon MB, Grube E. Results of the Jostent coronary stent graft implantation in various clinical settings: Procedural and follow‐up results. Catheterization And Cardiovascular Interventions 2002, 56: 353-360. PMID: 12112888, DOI: 10.1002/ccd.10223.Peer-Reviewed Original ResearchConceptsCoronary stent graftSaphenous vein graftsOverall restenosis rateStent graftRestenosis rateCoronary perforationStent restenosisAntiplatelet therapyVein graftsStent implantationComplex lesionsStent edgeStainless steel stentsHigh primary success ratePrimary angiographic success rateAngiographic success ratePrimary success ratePTFE layerIntravascular ultrasound guidanceLate lumen lossStent-graft implantationVein graft lesionsQ-wave MIComplex lesion subsetsTransient ventricular fibrillation
2001
Influence of gender on early and one-year clinical outcomes after saphenous vein graft stenting
Ahmed J, Dangas G, Lansky A, Mehran R, Hong M, Mintz G, Pichard A, Satler L, Kent K, Stone G, Leon M. Influence of gender on early and one-year clinical outcomes after saphenous vein graft stenting. The American Journal Of Cardiology 2001, 87: 401-405. PMID: 11179522, DOI: 10.1016/s0002-9149(00)01391-6.Peer-Reviewed Original ResearchConceptsAcute renal failureClinical outcomesSVG lesionsHospital mortalityVascular complicationsRenal failureProcedural successStent implantationFemale genderOne-year clinical outcomesSaphenous vein graft stentingLate clinical outcomesOverall procedural successSaphenous vein graftsVentricular ejection fractionInfluence of genderMultivariate regression analysisGraft stentingLesion revascularizationCoronary revascularizationConsecutive patientsDiabetes mellitusEjection fractionHospital eventsVein grafts
2000
Acute and long-term results of treatment of diffuse in-stent restenosis in aortocoronary saphenous vein grafts
Dangas G, Mehran R, Lansky A, Waksman R, Satler L, Pichard A, Kent K, Mintz G, Stone G, Leon M. Acute and long-term results of treatment of diffuse in-stent restenosis in aortocoronary saphenous vein grafts. The American Journal Of Cardiology 2000, 86: 777-779. PMID: 11018200, DOI: 10.1016/s0002-9149(00)01080-8.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnalysis of VarianceAngioplasty, Balloon, CoronaryAngioplasty, Balloon, Laser-AssistedCombined Modality TherapyCoronary Artery BypassCoronary Artery DiseaseFemaleGraft Occlusion, VascularHumansHyperplasiaMaleRecurrenceRisk FactorsSaphenous VeinStentsTreatment OutcomeUltrasonography, InterventionalConceptsSaphenous vein graftsVein graftsStent restenosisAortocoronary saphenous vein graftsHigher long-term mortalityExcimer laser coronary angioplastyAdjunct balloon angioplastyLong-term mortalityLaser coronary angioplastyTreatment of diffuseLong-term resultsRepeat revascularizationCoronary angioplastyAcute resultsBalloon angioplastyFrequent needAngioplastyRestenosisGraftTreatmentRevascularizationMortalityProcedural results and intermediate clinical outcomes after multiple saphenous vein graft stenting
Bhargava B, Kornowski R, Mehran R, Kent K, Hong M, Lansky A, Waksman R, Pichard A, Satler L, Leon M. Procedural results and intermediate clinical outcomes after multiple saphenous vein graft stenting. Journal Of The American College Of Cardiology 2000, 35: 389-397. PMID: 10676686, DOI: 10.1016/s0735-1097(99)00564-1.Peer-Reviewed Original ResearchConceptsMid-term clinical outcomesSVG interventionClinical outcomesProcedural successOverall cardiac event-free survivalCardiac event-free survivalSaphenous vein graft angioplastyNon-Q-wave MIHospital procedural successVein graft angioplastyEvent-free survivalIntermediate clinical outcomesMajor complication rateOverall procedural successSaphenous vein graftsGraft angioplastyLesion revascularizationSimultaneous stentingSVG diseaseSVG groupSVG stentingLate mortalityComplication rateDistal embolizationMI ratesComparison of time course of target lesion revascularization following successful saphenous vein graft angioplasty versus successful native coronary angioplasty
Hong M, Mehran R, Dangas G, Mintz G, Lansky A, Kent K, Pichard A, Satler L, Stone G, Leon M. Comparison of time course of target lesion revascularization following successful saphenous vein graft angioplasty versus successful native coronary angioplasty. The American Journal Of Cardiology 2000, 85: 256-258. PMID: 10955387, DOI: 10.1016/s0002-9149(99)00634-7.Peer-Reviewed Original Research
1999
In-hospital and long-term results of stent deployment compared with balloon angioplasty for treatment of narrowing at the saphenous vein graft distal anastomosis site
Gruberg L, Hong M, Mehran R, Mintz G, Kornowski R, Lansky A, Kent K, Pichard A, Satler L, Dangas G, Wu H, Stone G, Leon M. In-hospital and long-term results of stent deployment compared with balloon angioplasty for treatment of narrowing at the saphenous vein graft distal anastomosis site. The American Journal Of Cardiology 1999, 84: 1381-1384. PMID: 10606108, DOI: 10.1016/s0002-9149(99)00580-9.Peer-Reviewed Original ResearchConceptsSaphenous vein graftsDistal anastomosis siteLong-term outcomesBalloon angioplastyAnastomosis siteQ-wave myocardial infarction rateStent deploymentBalloon angioplasty groupMajor ischemic complicationsBaseline clinical characteristicsTarget lesion revascularizationMyocardial infarction rateProcedural success rateLower restenosis rateLong-term resultsRole of stentsHigh rateAngioplasty groupLesion revascularizationHospital outcomesInfarction rateIschemic complicationsPercutaneous revascularizationRepeat revascularizationClinical characteristicsLow- versus high-dose recombinant urokinase for the treatment of chronic saphenous vein graft occlusion
Teirstein P, Mann J, Cundey P, Schechter E, Jacobs W, Grines C, Stagaman D, Lansky A, Hultquist M, Kusnick B, Heuser R, Kleinert H, Popma J. Low- versus high-dose recombinant urokinase for the treatment of chronic saphenous vein graft occlusion. The American Journal Of Cardiology 1999, 83: 1623-1628. PMID: 10392865, DOI: 10.1016/s0002-9149(99)00163-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsCerebral HemorrhageChronic DiseaseCoronary AngiographyCoronary DiseaseDose-Response Relationship, DrugFemaleGraft Occlusion, VascularHeparinHumansInfusions, IntravenousMaleMiddle AgedPlasminogen ActivatorsRecombinant ProteinsSaphenous VeinUrokinase-Type Plasminogen ActivatorConceptsSaphenous vein graftsR-UKStudy drugVein graftsMyocardial infarctionNon-Q-wave myocardial infarctionPrimary study end pointSaphenous vein graft occlusionHigh-dose armStudy end pointLife-threatening bleedingVein graft occlusionHigh-dose groupDuration of infusionRecombinant urokinaseAcceptable success rateIntracerebral bleedPercutaneous revascularizationFinal angiogramGraft occlusionRecanalization rateAngiographic analysisHuman kidney cellsAllergic reactionsLow dose
1998
Procedural Results and Late Clinical Outcomes After Placement of Three or More Stents in Single Coronary Lesions
Kornowski R, Mehran R, Hong M, Satler L, Pichard A, Kent K, Mintz G, Waksman R, Laird J, Lansky A, Bucher T, Popma J, Leon M. Procedural Results and Late Clinical Outcomes After Placement of Three or More Stents in Single Coronary Lesions. Circulation 1998, 97: 1355-1361. PMID: 9577946, DOI: 10.1161/01.cir.97.14.1355.Peer-Reviewed Original ResearchConceptsNon-Q-wave MIUnfavorable lesion characteristicsClinical outcomesProcedural successMajor complicationsLesion characteristicsMultiple stentsOverall cardiac event-free survivalMajor cardiac event rateCardiac event-free survivalLong-term clinical outcomesCardiac event rateHospital procedural successLate clinical outcomesSingle coronary lesionsEvent-free survivalSaphenous vein graftsOverall procedural successRight coronary arteryLong-term complicationsQ-wave MILesion revascularizationConsecutive patientsCoronary lesionsLong dissection