2015
Pretreatment with aspirin in acute coronary syndromes: Lessons from the ACUITY and HORIZONS-AMI trials
Brener SJ, Mehran R, Lansky AJ, Ayele GM, Stone GW. Pretreatment with aspirin in acute coronary syndromes: Lessons from the ACUITY and HORIZONS-AMI trials. European Heart Journal Acute Cardiovascular Care 2015, 5: 449-454. PMID: 26722003, DOI: 10.1177/2048872615624848.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeHORIZONS-AMI trialCoronary syndromeAspirin pretreatmentMyocardial infarctionCardiac deathStent thrombosisSegment elevation acute coronary syndromesST-segment elevation myocardial infarctionElevation acute coronary syndromeAcute coronary syndrome patientsLarge randomized clinical trialsAdverse ischemic eventsTarget vessel revascularizationCoronary syndrome patientsIndependent risk factorElevation myocardial infarctionLarge prospective studiesHigh-risk cohortIncidence of deathRandomized clinical trialsMultivariable regression analysisPrior revascularizationVessel revascularizationIschemic events
2003
Comparison of the angiographic outcomes after beta versus gamma vascular brachytherapy for treatment of in-stent restenosis
Shirai K, Lansky AJ, Mintz GS, Costantini CO, Fahy M, Mehran R, Dangas G, Moses JW, Stone GW, Waksman R, Leon MB. Comparison of the angiographic outcomes after beta versus gamma vascular brachytherapy for treatment of in-stent restenosis. The American Journal Of Cardiology 2003, 92: 1409-1413. PMID: 14675575, DOI: 10.1016/j.amjcard.2003.08.047.Peer-Reviewed Original ResearchConceptsMinimum lumen diameterVascular brachytherapyLesion lengthSegment restenosisAngiographic outcomesStent restenosisFinal minimum lumen diameterRandomized clinical trialsIndependent angiographic predictorsAngiographic restenosisPlacebo groupAngiographic predictorsAngiographic resultsMultivariable analysisNative coronariesVessel sizeClinical trialsLesion complexityVBT groupRestenosisLumen diameterSimilar reductionPlaceboGreater reductionLesions
1999
Intracoronary radiation for patients with refractory in-stent restenosis An analysis from the wrist-crossover trial
Waksman R, Bhargava B, White R, Chan R, Gierlach L, Mehran R, Lansky A, Kent K, Mintz G, Satler L, Pichard A, Leon M. Intracoronary radiation for patients with refractory in-stent restenosis An analysis from the wrist-crossover trial. Cardiovascular Revascularization Medicine 1999, 1: 317-322. PMID: 10828560, DOI: 10.1016/s1522-1865(00)00024-x.Peer-Reviewed Original ResearchConceptsPrimary treatment groupTarget lesion revascularizationCrossover groupStent restenosisTreatment groupsClinical trialsQ-wave myocardial infarctionStent restenosis TrialAdverse cardiac eventsPrimary clinical endpointIntracoronary stent implantationRandomized clinical trialsCatheter-based interventionsCatheter-based techniquesStent neointimal formationAnginal symptomsLesion revascularizationRecurrent ISRRestenosis TrialActive therapyAngiographic outcomesCardiac eventsPlacebo armProcedural successIntracoronary radiation