2010
Incidence, Mechanisms, Predictors, and Clinical Impact of Acute and Late Stent Malapposition After Primary Intervention in Patients With Acute Myocardial Infarction
Guo N, Maehara A, Mintz GS, He Y, Xu K, Wu X, Lansky AJ, Witzenbichler B, Guagliumi G, Brodie B, Kellett MA, Dressler O, Parise H, Mehran R, Stone GW. Incidence, Mechanisms, Predictors, and Clinical Impact of Acute and Late Stent Malapposition After Primary Intervention in Patients With Acute Myocardial Infarction. Circulation 2010, 122: 1077-1084. PMID: 20805433, DOI: 10.1161/circulationaha.109.906040.Peer-Reviewed Original ResearchConceptsAcute stent malappositionPaclitaxel-eluting stentsBare metal stentsLate stent malappositionPES-treated lesionsStent malappositionPositive remodelingMyocardial infarctionST-segment elevation myocardial infarction (STEMI) patientsST-segment elevation myocardial infarctionEquivalent bare metal stentsAcute Myocardial Infarction trialElevation myocardial infarction patientsASM areaExternal elastic membrane areaIntravascular ultrasound substudyPeri-stent plaquePrimary stent implantationMyocardial Infarction trialNative coronary lesionsElevation myocardial infarctionAcute myocardial infarctionMyocardial infarction patientsSubset of lesionsExternal elastic membrane
2006
Safety of beta radiation exposure to the non-target segment: an intravascular ultrasound dosimetric analysis.
Kaneda H, Honda Y, Morino Y, Fox T, Crocker I, Lansky AJ, Yock PG, Bonan R, Fitzgerald PJ. Safety of beta radiation exposure to the non-target segment: an intravascular ultrasound dosimetric analysis. Journal Of Invasive Cardiology 2006, 18: 309-12. PMID: 16816435.Peer-Reviewed Original ResearchConceptsDosimetric analysisDistal segmentsRadiation exposureDistal reference sitesStent restenosis casesSignificant serial changesGreater radiation exposurePositive vessel remodelingRestenosis casesBeta radiation exposureLumen lossPositive remodelingCoronary arteryPlaque volumeGeographic missPlaque areaDistal vasculatureSerial changesPlaque massPlaque increasePrescribed doseVessel changesMild increaseMinimum doseVessel remodelingIntravascular Ultrasonic Differences Between Aorto-Ostial and Shaft Narrowing in Saphenous Veins Used as Aortocoronary Bypass Grafts
Sano K, Mintz GS, Carlier SG, Fujii K, Yasuda T, Kimura M, Costa JR, Costa RA, Lui J, Weisz G, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Intravascular Ultrasonic Differences Between Aorto-Ostial and Shaft Narrowing in Saphenous Veins Used as Aortocoronary Bypass Grafts. The American Journal Of Cardiology 2006, 97: 1463-1466. PMID: 16679084, DOI: 10.1016/j.amjcard.2005.11.080.Peer-Reviewed Original ResearchConceptsMinimal lumen areaAorto-ostial lesionsPositive remodelingShaft lesionsLumen areaPlaque burdenDistal referenceSoft plaqueAortocoronary bypass graftsLarger plaque burdenSVG lesionsComplication rateBypass graftInterventional complicationsSaphenous veinLesion locationLesionsMorphologic differencesRemodelingPlaquesIVUS dataLocation-specific differencesBurdenIntravascular ultrasound imagesPrevious studies
2003
Correlation of coronary arterial remodeling determined by intravascular ultrasound with angiographic diameter reduction of 20% to 60%
Hirose M, Kobayashi Y, Mintz GS, Moussa I, Mehran R, Lansky AJ, Dangas G, Kreps EM, Collins MB, Stone GW, Colombo A, Leon MB, Moses JW. Correlation of coronary arterial remodeling determined by intravascular ultrasound with angiographic diameter reduction of 20% to 60%. The American Journal Of Cardiology 2003, 92: 141-145. PMID: 12860214, DOI: 10.1016/s0002-9149(03)00528-9.Peer-Reviewed Original ResearchConceptsEEM cross-sectional areaNegative remodelingIntermediate remodelingPositive remodelingIntermediate stenosisCoronary lesionsCross-sectional areaDistal referenceIntravascular ultrasoundExternal elastic membrane cross-sectional areaLumen cross-sectional areaPreintervention intravascular ultrasoundStenotic coronary lesionsNative coronary lesionsCoronary arterial remodelingCoronary stenosisArterial remodelingProximal referenceLess plaqueArea stenosisStenosisLesionsLesion formationHard plaquesRemodeling occurs
2001
Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions
Ahmed J, Mintz G, Waksman R, Lansky A, Mehran R, Wu H, Weissman N, Pichard A, Satler L, Kent K, Leon M. Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions. The American Journal Of Cardiology 2001, 87: 1145-1149. PMID: 11356387, DOI: 10.1016/s0002-9149(01)01483-7.Peer-Reviewed Original ResearchConceptsLumen cross-sectional areaIntimal hyperplasia cross-sectional areaSerial intravascular ultrasound analysisMedia cross-sectional areaEdge recurrenceIntravascular ultrasound analysisCross-sectional areaStent restenosisExternal elastic membrane cross-sectional areaUltrasound analysisStent restenosis TrialStent restenosis lesionsDistal cross-sectional areasGreater decreaseGreater increaseRestenosis lesionsRestenosis TrialPositive remodelingProximal plaqueWashington RadiationNative coronariesMean lumenNeointimal hyperplasiaRecurrenceLesions
1999
Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention
Dangas G, Mintz G, Mehran R, Lansky A, Kornowski R, Pichard A, Satler L, Kent K, Stone G, Leon M. Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention. Circulation 1999, 99: 3149-3154. PMID: 10377078, DOI: 10.1161/01.cir.99.24.3149.Peer-Reviewed Original ResearchConceptsIndependent predictorsArterial remodelingTarget lesion revascularization rateInsulin-dependent diabetic patientsLong-term clinical outcomesQ-wave myocardial infarctionMultivariable logistic regression analysisTarget lesion revascularizationShort-term complicationsIntravascular ultrasound studyLong-term outcomesFinal lumen areaLogistic regression analysisIntermediate remodelingAngiographic characteristicsAngiographic successRevascularization ratesCoronary interventionClinical outcomesDiabetic patientsPlaque burdenPositive remodelingMyocardial infarctionNegative remodelingPercutaneous intervention
1998
Intracoronary Radiation Post PTCA Prevents Late Arterial Constriction
WAKSMAN R, CONDADO J, SAUCEDO J, LANSKY A, POPMA J, KLEIN J, CROCKER I, WILLIAMS D, KING S. Intracoronary Radiation Post PTCA Prevents Late Arterial Constriction. Journal Of Interventional Cardiology 1998, 11: 535-541. DOI: 10.1111/j.1540-8183.1998.tb00165.x.Peer-Reviewed Original ResearchPost-PTCABalloon angioplastyIntracoronary radiationLate lossLate loss indexLower late lossVascular remodeling effectDe novo lesionsIntracoronary radiation therapyPilot clinical studyMechanism of restenosisNovo lesionsRestenosis rateRadiation trialsPositive remodelingTotal occlusionArterial constrictionClinical studiesVascular remodelingRadiation therapyNeointima formationAnimal modelsPatientsRemodeling effectTrials