2013
Impact of advanced age on the safety and effectiveness of paclitaxel‐eluting stent implantation in patients with ST‐segment elevation myocardial infarction undergoing primary angioplasty
Dudek D, Mehran R, Dziewierz A, Witzenbichler B, Brodie BR, Kornowski R, Fahy M, Lansky AJ, Rakowski T, Legutko J, Bryniarski L, Stone GW. Impact of advanced age on the safety and effectiveness of paclitaxel‐eluting stent implantation in patients with ST‐segment elevation myocardial infarction undergoing primary angioplasty. Catheterization And Cardiovascular Interventions 2013, 82: 869-877. PMID: 23359554, DOI: 10.1002/ccd.24813.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionPaclitaxel-eluting stent implantationPrimary PCIBare metal stentsElevation myocardial infarctionYears of ageStent implantationOlder patientsMyocardial infarctionLower riskIschemic target vessel revascularizationMajor adverse cardiac eventsHORIZONS-AMI studyHORIZONS-AMI trialReduction of MACEAdverse cardiac eventsTarget vessel revascularizationClinical end pointsPercutaneous coronary interventionLong-term resultsImpact of ageCause deathMajor bleedingPrimary angioplasty
2011
Impact of Smoking on Outcomes of Patients With ST-Segment Elevation Myocardial Infarction (from the HORIZONS-AMI Trial)
Goto K, Nikolsky E, Lansky AJ, Dangas G, Witzenbichler B, Parise H, Guagliumi G, Kornowski R, Claessen BE, Fahy M, Mehran R, Stone GW. Impact of Smoking on Outcomes of Patients With ST-Segment Elevation Myocardial Infarction (from the HORIZONS-AMI Trial). The American Journal Of Cardiology 2011, 108: 1387-1394. PMID: 21864816, DOI: 10.1016/j.amjcard.2011.06.063.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAntithrombinsCoronary AngiographyCoronary RestenosisCoronary ThrombosisDrug Therapy, CombinationDrug UtilizationFemaleHemorrhageHeparinHirudinsHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPaclitaxelPeptide FragmentsPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexPyridinesRecombinant ProteinsSmokingStentsConceptsGlycoprotein IIb/IIIa inhibitorsST-segment elevation myocardial infarctionElevation myocardial infarctionPrimary percutaneous coronary interventionProbable stent thrombosisPercutaneous coronary interventionUnfractionated heparinStent thrombosisMajor bleedingMyocardial infarctionBivalirudin monotherapyCoronary interventionSmoking statusPaclitaxel-eluting stent implantationIIb/IIIa inhibitorsAlternative antithrombotic regimensHORIZONS-AMI trialOutcomes of patientsImpact of smokingPaclitaxel-eluting stentsBare metal stentsLate stent thrombosisAntithrombotic regimensIschemic eventsIndependent predictors
2005
Gender-based outcomes after paclitaxel-eluting stent implantation in patients with coronary artery disease
Lansky AJ, Costa RA, Mooney M, Midei MG, Lui HK, Strickland W, Mehran R, Leon MB, Russell ME, Ellis SG, Stone GW, Investigators T. Gender-based outcomes after paclitaxel-eluting stent implantation in patients with coronary artery disease. Journal Of The American College Of Cardiology 2005, 45: 1180-1185. PMID: 15837246, DOI: 10.1016/j.jacc.2004.10.076.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationPaclitaxel-eluting stent implantationIndependent predictorsStent implantationTaxus stentPaclitaxel-eluting Taxus stentElective coronary interventionTAXUS-IV trialOnly independent predictorCoronary artery diseaseOne-year ratesGender-based outcomesBare metal stentsLesion revascularizationMore hypertensionAngiographic restenosisRenal insufficiencyCoronary interventionUnstable anginaArtery diseaseHeart failureRestenosis rateLess smokingFemale genderLate loss