2015
Pretreatment with aspirin in acute coronary syndromes: Lessons from the ACUITY and HORIZONS-AMI trials
Brener SJ, Mehran R, Lansky AJ, Ayele GM, Stone GW. Pretreatment with aspirin in acute coronary syndromes: Lessons from the ACUITY and HORIZONS-AMI trials. European Heart Journal Acute Cardiovascular Care 2015, 5: 449-454. PMID: 26722003, DOI: 10.1177/2048872615624848.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeHORIZONS-AMI trialCoronary syndromeAspirin pretreatmentMyocardial infarctionCardiac deathStent thrombosisSegment elevation acute coronary syndromesST-segment elevation myocardial infarctionElevation acute coronary syndromeAcute coronary syndrome patientsLarge randomized clinical trialsAdverse ischemic eventsTarget vessel revascularizationCoronary syndrome patientsIndependent risk factorElevation myocardial infarctionLarge prospective studiesHigh-risk cohortIncidence of deathRandomized clinical trialsMultivariable regression analysisPrior revascularizationVessel revascularizationIschemic events
2004
Comparison of differences in outcome after percutaneous coronary intervention in men versus women <40 years of age
Lansky AJ, Mehran R, Dangas G, Cristea E, Shirai K, Costa R, Costantini C, Tsuchiya Y, Carlier S, Mintz G, Cottin Y, Stone G, Moses J, Leon MB. Comparison of differences in outcome after percutaneous coronary intervention in men versus women <40 years of age. The American Journal Of Cardiology 2004, 93: 916-919. PMID: 15050498, DOI: 10.1016/j.amjcard.2003.12.046.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionYears of ageCoronary interventionVascular complicationsMyocardial infarctionMortality rateAggressive risk factor modificationQ-wave myocardial infarctionHospital vascular complicationsMore diabetes mellitusPredominance of diabetesNonfatal myocardial infarctionRisk factor modificationPremature coronary diseaseRisk factor profileOnly independent predictorMultivariable regression analysisLess hyperlipidemiaIschemic complicationsConsecutive patientsCoronary diseaseDiabetes mellitusIndependent predictorsPremature atherosclerosisFactor modification