2023
TCT-240 A-SMART-EF: A Novel Score to Predict Mortality in Patients Undergoing Impella-Assisted Percutaneous Coronary Intervention
Lemor A, Shah T, Thompson J, Protty M, Mamas M, Kinnaird T, Bharadwaj A, Truesdell A, Zhang Y, Cohen D, Falah B, Redfors B, Baron S, Witzke C, Dixon S, Lansky A, Basir B, O’Neill W. TCT-240 A-SMART-EF: A Novel Score to Predict Mortality in Patients Undergoing Impella-Assisted Percutaneous Coronary Intervention. Journal Of The American College Of Cardiology 2023, 82: b93-b94. DOI: 10.1016/j.jacc.2023.09.247.Peer-Reviewed Original ResearchEffects of Elective Coronary Revascularization vs Medical Therapy Alone on Noncardiac Mortality A Meta-Analysis
Navarese E, Lansky A, Farkouh M, Grzelakowska K, Bonaca M, Gorog D, Raggi P, Kelm M, Yeo B, Umińska J, Curzen N, Kubica J, Wijns W, Kereiakes D. Effects of Elective Coronary Revascularization vs Medical Therapy Alone on Noncardiac Mortality A Meta-Analysis. JACC Cardiovascular Interventions 2023, 16: 1144-1156. PMID: 37225285, DOI: 10.1016/j.jcin.2023.02.030.Peer-Reviewed Original ResearchConceptsChronic coronary syndromeElective coronary revascularizationNoncardiac mortalityMedical therapyCoronary revascularizationTrial sequential analysisCumulative Z-curveRate ratioA Meta-AnalysisRandom-effects modelMeta-analysis findingsCoronary syndromeISCHEMIA trialRandomized trialsTrial evidenceRevascularizationTreatment groupsPrespecified endpointsMeta-AnalysisPatientsMortalityFutility boundariesDeath rateTrialsTreatment effects
2021
Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention
O'Neill BP, Grines C, Moses JW, Ohman EM, Lansky A, Popma J, Kapur NK, Schreiber T, Mannino S, O'Neill WW, Medjamia AM, Mahmud E. Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention. Catheterization And Cardiovascular Interventions 2021, 98: e501-e512. PMID: 34051033, DOI: 10.1002/ccd.29758.Peer-Reviewed Original ResearchConceptsPercutaneous ventricular assist deviceNonemergent percutaneous coronary interventionPercutaneous coronary interventionHemodynamic collapseVentricular assist deviceCoronary interventionProphylactic supportImpella percutaneous ventricular assist deviceAssist deviceOutcomes of patientsVentricular ejection fractionHospital mortalityHospital outcomesEjection fractionHeart failureMedian baselinePVAD supportProphylactic strategiesFemale genderStudy populationLow prevalencePatientsMain diseaseOutcomesMortality
2017
What is the best ST-segment recovery parameter to predict clinical outcome and myocardial infarct size? Amplitude, speed, and completeness of ST-segment recovery after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Kuijt WJ, Green CL, Verouden NJW, Haeck JDE, Tzivoni D, Koch KT, Stone GW, Lansky AJ, Broderick S, Tijssen JGP, de Winter RJ, Roe MT, Krucoff MW. What is the best ST-segment recovery parameter to predict clinical outcome and myocardial infarct size? Amplitude, speed, and completeness of ST-segment recovery after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Journal Of Electrocardiology 2017, 50: 952-959. PMID: 29153151, DOI: 10.1016/j.jelectrocard.2017.04.009.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionST-segment recoveryPrimary percutaneous coronary interventionPercutaneous coronary interventionElevation myocardial infarctionInfarct sizeCoronary interventionMyocardial infarctionHolter ECG monitoringMyocardial infarct sizeSingle photon emissionMultivariable adjustmentClinical outcomesRisk factorsClinical trialsNoninvasive biomarkersCore laboratoryMechanistic correlatesMortalityECG monitoringInfarctionRecovery parametersST parametersInterventionOutcomes
2013
Selection and timing for invasive therapy in non-ST-segment-elevation acute coronary syndrome
Meier P, Fröhlich GM, Meller S, De Palma R, Lansky AJ. Selection and timing for invasive therapy in non-ST-segment-elevation acute coronary syndrome. Expert Review Of Cardiovascular Therapy 2013, 11: 437-445. PMID: 23570357, DOI: 10.1586/erc.13.23.Peer-Reviewed Original ResearchConceptsSegment elevation acute coronary syndromesST-segment elevation myocardial infarctionAcute coronary syndromeCoronary syndromeMyocardial infarctionLong-term mortalityBest treatment strategyOptimal time pointNSTEACS patientsTerm mortalityCoronary angiographyOptimal therapyPoor prognosisTreatment strategiesInvasive therapyHigh mortalityOlder agePatientsTime pointsMortalityNSTEACSInfarctionSyndromeTherapyAngiographyTHE IMPACT OF ELECTROCARDIOGRAPHIC LEFT VENTRICULAR HYPERTROPHY ON MORTALITY IN PATIENTS WITH STEMI UNDERGOING PRIMARY PCI: ANALYSIS FROM THE HORIZONS–AMI TRIAL
Lansky A, Ng V, Fahy M, Dizon J, Mehran R, Stone G. THE IMPACT OF ELECTROCARDIOGRAPHIC LEFT VENTRICULAR HYPERTROPHY ON MORTALITY IN PATIENTS WITH STEMI UNDERGOING PRIMARY PCI: ANALYSIS FROM THE HORIZONS–AMI TRIAL. Journal Of The American College Of Cardiology 2013, 61: e1884. DOI: 10.1016/s0735-1097(13)61884-7.Peer-Reviewed Original Research
2011
Relationship between angiographic dynamic and densitometric assessment of myocardial reperfusion and survival in patients with acute myocardial infarction treated with primary percutaneous coronary intervention: The Harmonizing Outcomes with Revascularization and Stents in AMI (HORIZONS-AMI) trial
Brener SJ, Cristea E, Mehran R, Dressler O, Lansky AJ, Stone GW. Relationship between angiographic dynamic and densitometric assessment of myocardial reperfusion and survival in patients with acute myocardial infarction treated with primary percutaneous coronary intervention: The Harmonizing Outcomes with Revascularization and Stents in AMI (HORIZONS-AMI) trial. American Heart Journal 2011, 162: 1044-1051. PMID: 22137078, DOI: 10.1016/j.ahj.2011.08.022.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionPercutaneous coronary interventionCoronary interventionIndependent predictorsMyocardial infarctionMyocardial perfusionHORIZONS-AMI studyEarly clinical outcomesLong-term mortalityElevation myocardial infarctionAcute myocardial infarctionHarmonizing OutcomesLate mortalityAMI trialEpicardial flowMyocardial reperfusionClinical outcomesGrade 2/3Multivariable analysisLate survivalPatientsMortalityTime pointsDensitometric assessment
2010
IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ACUTE CORONARY SYNDROMES: ANALYSIS OF THE ACUTE CATHETERIZATION AND URGENT INTERVENTION TRIAGE STRATEGY (ACUITY) TRIAL
Lansky A, Ng V, Goto K, Fahy M, Mehran R, Ebrahimian R, Hamond M, Ohman E, Feit F, Manoukian S, Lincoff M, Stone G. IMPACT OF LEFT VENTRICULAR FUNCTION ON MORTALITY IN PATIENTS WITH ACUTE CORONARY SYNDROMES: ANALYSIS OF THE ACUTE CATHETERIZATION AND URGENT INTERVENTION TRIAGE STRATEGY (ACUITY) TRIAL. Journal Of The American College Of Cardiology 2010, 55: a186.e1740. DOI: 10.1016/s0735-1097(10)61741-x.Peer-Reviewed Original Research
2009
Prognostic Significance of Periprocedural Versus Spontaneously Occurring Myocardial Infarction After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndromes An Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) Trial
Prasad A, Gersh BJ, Bertrand ME, Lincoff AM, Moses JW, Ohman EM, White HD, Pocock SJ, McLaurin BT, Cox DA, Lansky AJ, Mehran R, Stone GW. Prognostic Significance of Periprocedural Versus Spontaneously Occurring Myocardial Infarction After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndromes An Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) Trial. Journal Of The American College Of Cardiology 2009, 54: 477-486. PMID: 19628125, DOI: 10.1016/j.jacc.2009.03.063.Peer-Reviewed Original ResearchConceptsPeriprocedural myocardial infarctionPercutaneous coronary interventionAcute coronary syndromeSpontaneous myocardial infarctionMyocardial infarctionCoronary syndromeACUITY trialCoronary interventionPrognostic significanceSubsequent mortalitySegment elevation acute coronary syndromesElevation acute coronary syndromePowerful independent predictorIndependent prognostic significanceAtherosclerosis burdenIndependent predictorsMultivariable analysisUnadjusted ratesProcedural characteristicsBaseline riskClinical significancePatientsMortalitySyndromeSpontaneous development
2004
Prognostic significance of cerebrovascular and peripheral arterial disease in patients having percutaneous coronary interventions
Nikolsky E, Mehran R, Dangas GD, Lasic Z, Mintz GS, Negoita M, Lansky AJ, Stone GW, Moussa I, Iyer S, Na Y, Moses JW, Leon MB. Prognostic significance of cerebrovascular and peripheral arterial disease in patients having percutaneous coronary interventions. The American Journal Of Cardiology 2004, 93: 1536-1539. PMID: 15194030, DOI: 10.1016/j.amjcard.2004.03.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAngioplasty, Balloon, CoronaryBody Mass IndexCase-Control StudiesCerebrovascular DisordersCoronary Artery DiseaseDiabetes ComplicationsFemaleHospital MortalityHumansKidney Failure, ChronicLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisPeripheral Vascular DiseasesPrognosisSaphenous VeinSex Factors
2003
ST-segment elevation resolution as a predictor of mortality in patients with thrombolysis in myocardial infarction III flow in the infarct artery after primary angioplasty: The CADILLAC trial
McLaughlin M, Gardner G, Aymong E, Mehran R, Lansky A, Grines C, Tcheng J, Cox D, Stuckey T, Garcia E, Guagliumi G, Turco M, Zimetbaum P, Stone G. ST-segment elevation resolution as a predictor of mortality in patients with thrombolysis in myocardial infarction III flow in the infarct artery after primary angioplasty: The CADILLAC trial. Journal Of The American College Of Cardiology 2003, 41: 392. DOI: 10.1016/s0735-1097(03)81128-2.Peer-Reviewed Original ResearchImpact of gender on the incidence and outcome of contrast-induced nephropathy after percutaneous coronary intervention.
Iakovou I, Dangas G, Mehran R, Lansky AJ, Ashby DT, Fahy M, Mintz GS, Kent KM, Pichard AD, Satler LF, Stone GW, Leon MB. Impact of gender on the incidence and outcome of contrast-induced nephropathy after percutaneous coronary intervention. Journal Of Invasive Cardiology 2003, 15: 18-22. PMID: 12499523.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyChronic renal failureOne-year mortalityIndependent predictorsPercutaneous interventionDiabetes mellitusClinical outcomesFemale genderMultivariate analysisOne-year clinical eventsNYHA IV classSevere heart failurePercutaneous coronary interventionImpact of genderCoronary interventionRenal failureHeart failureMale patientsCIN developmentClinical eventsPatientsMortalityMellitusNephropathySignificant gender differences
2002
Postprocedure creatine kinase-MB elevation and baseline left ventricular dysfunction predict one-year mortality after percutaneous coronary intervention
Dangas G, Mehran R, Feldman D, Stoyioglou A, Pichard AD, Kent KM, Satler LF, Fahy M, Lansky AJ, Stone GW, Leon MB. Postprocedure creatine kinase-MB elevation and baseline left ventricular dysfunction predict one-year mortality after percutaneous coronary intervention. The American Journal Of Cardiology 2002, 89: 586-589. PMID: 11867045, DOI: 10.1016/s0002-9149(01)02299-8.Peer-Reviewed Original Research
2000
Acute and long-term results of treatment of diffuse in-stent restenosis in aortocoronary saphenous vein grafts
Dangas G, Mehran R, Lansky A, Waksman R, Satler L, Pichard A, Kent K, Mintz G, Stone G, Leon M. Acute and long-term results of treatment of diffuse in-stent restenosis in aortocoronary saphenous vein grafts. The American Journal Of Cardiology 2000, 86: 777-779. PMID: 11018200, DOI: 10.1016/s0002-9149(00)01080-8.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnalysis of VarianceAngioplasty, Balloon, CoronaryAngioplasty, Balloon, Laser-AssistedCombined Modality TherapyCoronary Artery BypassCoronary Artery DiseaseFemaleGraft Occlusion, VascularHumansHyperplasiaMaleRecurrenceRisk FactorsSaphenous VeinStentsTreatment OutcomeUltrasonography, InterventionalConceptsSaphenous vein graftsVein graftsStent restenosisAortocoronary saphenous vein graftsHigher long-term mortalityExcimer laser coronary angioplastyAdjunct balloon angioplastyLong-term mortalityLaser coronary angioplastyTreatment of diffuseLong-term resultsRepeat revascularizationCoronary angioplastyAcute resultsBalloon angioplastyFrequent needAngioplastyRestenosisGraftTreatmentRevascularizationMortality