2013
Efficacy and safety of FIREHAWK® abluminal groove filled biodegradable polymer sirolimus-eluting stents for the treatment of long coronary lesions: nine-month angiographic and one-year clinical results from TARGET I trial long cohort.
Xu B, Gao RL, Zhang RY, Wang HC, Li ZQ, Yang YJ, Ma CS, Han YL, Lansky AJ, Huo Y, Li W, Leon MB. Efficacy and safety of FIREHAWK® abluminal groove filled biodegradable polymer sirolimus-eluting stents for the treatment of long coronary lesions: nine-month angiographic and one-year clinical results from TARGET I trial long cohort. Chinese Medical Journal 2013, 126: 1026-32. PMID: 23506573, DOI: 10.3760/cma.j.issn.0366-6999.20123206.Peer-Reviewed Original ResearchConceptsLong coronary lesionsPercutaneous coronary interventionCoronary lesionsMyocardial infarctionLate lossLONG cohortLong lesionsBiodegradable polymer sirolimus-eluting stentsNon-Q-wave myocardial infarctionDrug-eluting stent (DES) failureLong coronary artery diseaseStent late lumen lossOne-year clinical resultsSegment binary restenosisSegment late lossPrimary end pointReference vessel diameterLate lumen lossNative coronary arteriesStent late lossCoronary artery diseaseMajor inclusion criteriaSingle-arm trialSirolimus-eluting stentsAbluminal groove
2011
Impact of Lesion Length and Vessel Size on Clinical Outcomes After Percutaneous Coronary Intervention With Everolimus- Versus Paclitaxel-Eluting Stents Pooled Analysis From the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials
Claessen BE, Smits PC, Kereiakes DJ, Parise H, Fahy M, Kedhi E, Serruys PW, Lansky AJ, Cristea E, Sudhir K, Sood P, Simonton CA, Stone GW. Impact of Lesion Length and Vessel Size on Clinical Outcomes After Percutaneous Coronary Intervention With Everolimus- Versus Paclitaxel-Eluting Stents Pooled Analysis From the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials. JACC Cardiovascular Interventions 2011, 4: 1209-1215. PMID: 22115661, DOI: 10.1016/j.jcin.2011.07.016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCardiovascular AgentsChi-Square DistributionCoronary AngiographyCoronary StenosisDrug-Eluting StentsEverolimusFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionPaclitaxelPredictive Value of TestsProportional Hazards ModelsProsthesis DesignRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsSeverity of Illness IndexSirolimusThrombosisTime FactorsTreatment OutcomeConceptsMajor adverse cardiac eventsPaclitaxel-eluting stentsReference vessel diameterEverolimus-eluting stentsPercutaneous coronary interventionLong lesionsGroup BLesion lengthMACE rateCoronary interventionSmall vesselsGroup AStent typeShort lesionsAdverse cardiac eventsHigh-risk patientsPatient-level dataLarge vesselsLower ratesCOMPARE trialLesion revascularizationEfficacy outcomesAdverse eventsCardiac eventsIndependent predictors
2003
Beta radiation in lesions > 15 mm: a START subgroup.
Heuser R, Laskey W, Lansky A, Popma J, Bonan R. Beta radiation in lesions > 15 mm: a START subgroup. Journal Of Invasive Cardiology 2003, 15: 641-3. PMID: 14608136.Peer-Reviewed Original ResearchConceptsPlacebo groupLong lesionsStent restenosisSTART trialMajor adverse cardiac eventsAngiographic lesion characteristicsIntracoronary beta radiationAdverse cardiac eventsBinary restenosis rateIncidence of recurrentMean lesion lengthSignificant reductionLesion revascularizationRecurrent restenosisVessel revascularizationAngiographic parametersCardiac eventsClinical restenosisPatient demographicsRestenosis rateCoronary lesionsStent thrombosisLesion characteristicsRadiation groupRadiation therapy
2002
Localized intracoronary beta radiation therapy to inhibit recurrence of in-stent restenosis
Waksman R, Raizner A, Yeung A, Lansky A, Vandertie L, on behalf of the INHIBIT Investigators. Localized intracoronary beta radiation therapy to inhibit recurrence of in-stent restenosis. Clinical Research In Cardiology 2002, 91: 40-41. DOI: 10.1007/s00392-002-1307-z.Peer-Reviewed Original ResearchTarget lesion revascularizationMajor adverse cardiac eventsPrimary safety endpointTarget vessel revascularizationLesion revascularizationStent restenosisMyocardial infarctionSafety endpointRestenosis rateRadiated groupLong lesionsRadiation therapyBinary angiographic restenosis rateIntracoronary beta-radiation therapyBeta-radiation therapyIntracoronary beta radiationSuccessful coronary interventionAdverse cardiac eventsAngiographic restenosis ratePrimary efficacy endpointIntracoronary radiation therapyRecurrence of restenosisCentering catheterOverall revascularizationEfficacy endpoint
2001
Analysis of clinical outcomes from the START and START 40 trials: the efficacy of SR-90 radiation in the treatment of long lesion in stent restenosis
Suntharalingam M, Laskey W, Lansky A, Crocker I, Popma J, Bonan R, Kuntz R. Analysis of clinical outcomes from the START and START 40 trials: the efficacy of SR-90 radiation in the treatment of long lesion in stent restenosis. International Journal Of Radiation Oncology • Biology • Physics 2001, 51: 142-143. DOI: 10.1016/s0360-3016(01)02081-8.Peer-Reviewed Original Research
2000
Importance of lesion length on new device angioplasty of native coronary arteries
Saucedo J, Kennard E, Popma J, Talley D, Lansky A, Leon M, Baim D. Importance of lesion length on new device angioplasty of native coronary arteries. Catheterization And Cardiovascular Interventions 2000, 50: 19-25. PMID: 10816274, DOI: 10.1002/(sici)1522-726x(200005)50:1<19::aid-ccd4>3.0.co;2-h.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationNew device angioplastyMore target lesion revascularizationLesion revascularizationLong lesionsLesion lengthRight coronary artery diseaseSmaller minimal lumen diameterLong lesion groupMore multivessel diseaseNative coronary arteriesCoronary artery diseaseCoronary Intervention RegistryEarly clinical eventsMinimal lumen diameterLonger lesion lengthMultivessel diseaseAngiographic outcomesIntervention RegistryArtery diseaseClinical outcomesHospital eventsTotal occlusionClinical eventsCoronary artery