2024
Association of Preprocedural SYNTAX Score With Outcomes in Impella-Assisted High-Risk Percutaneous Coronary Intervention
Medranda G, Faraz H, Thompson J, Zhang Y, Bharadwaj A, Osborn E, Abu-Much A, Lansky A, Basir M, Moses J, O’Neill W, Grines C, Baron S. Association of Preprocedural SYNTAX Score With Outcomes in Impella-Assisted High-Risk Percutaneous Coronary Intervention. Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 101981. PMID: 39166169, PMCID: PMC11330901, DOI: 10.1016/j.jscai.2024.101981.Peer-Reviewed Original ResearchSYNTAX I scoreHigh-risk percutaneous coronary interventionPercutaneous coronary interventionCoronary interventionSYNTAX IIII studiesSYNTAX scoreI scoresAssociated with higher ratesComplex coronary artery diseaseCoronary artery diseaseMultivariate regression analysisMechanical circulatory supportInterventionClinical outcomesPoor outcomeCerebrovascular eventsRegression analysisArtery diseasePost-PCIPatientsCirculatory supportProcedural factorsHigher ratesOutcomes
2023
TCT-216 Defining High-Risk Percutaneous Coronary Intervention: Characteristics of Patients Undergoing Contemporary Percutaneous Coronary Intervention With Axial-Flow Mechanical Support
Bharadwaj A, Truesdell A, Lemor A, Thompson J, Abu-Much A, Zhang Y, Schonning M, Redfors B, Cohen D, Witzke C, Matthews R, Dixon S, Lansky A, O’Neill W. TCT-216 Defining High-Risk Percutaneous Coronary Intervention: Characteristics of Patients Undergoing Contemporary Percutaneous Coronary Intervention With Axial-Flow Mechanical Support. Journal Of The American College Of Cardiology 2023, 82: b83-b84. DOI: 10.1016/j.jacc.2023.09.223.Peer-Reviewed Original Research
2018
Cerebral Embolic Risk During Transcatheter Mitral Valve Interventions An Unaddressed and Unmet Clinical Need?
Pagnesi M, Regazzoli D, Ancona MB, Mangieri A, Lanzillo G, Giannini F, Buzzatti N, Prendergast BD, Kodali S, Lansky AJ, Colombo A, Latib A. Cerebral Embolic Risk During Transcatheter Mitral Valve Interventions An Unaddressed and Unmet Clinical Need? JACC Cardiovascular Interventions 2018, 11: 517-528. PMID: 29566796, DOI: 10.1016/j.jcin.2017.12.018.Peer-Reviewed Original ResearchConceptsTranscatheter mitral valve interventionsCerebral embolic riskMitral valve interventionMV proceduresEmbolic riskValve interventionHeart interventionsProcedure-related adverse eventsPatient-related factorsStructural heart interventionsReal clinical issueMV interventionAdverse eventsEmbolic injuryMV diseaseUnmet ClinicalMV anatomyClinical issuesAvailable evidenceInterventionRiskSystematic assessmentClinicalInjuryAvailable data
2017
What is the best ST-segment recovery parameter to predict clinical outcome and myocardial infarct size? Amplitude, speed, and completeness of ST-segment recovery after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Kuijt WJ, Green CL, Verouden NJW, Haeck JDE, Tzivoni D, Koch KT, Stone GW, Lansky AJ, Broderick S, Tijssen JGP, de Winter RJ, Roe MT, Krucoff MW. What is the best ST-segment recovery parameter to predict clinical outcome and myocardial infarct size? Amplitude, speed, and completeness of ST-segment recovery after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Journal Of Electrocardiology 2017, 50: 952-959. PMID: 29153151, DOI: 10.1016/j.jelectrocard.2017.04.009.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionST-segment recoveryPrimary percutaneous coronary interventionPercutaneous coronary interventionElevation myocardial infarctionInfarct sizeCoronary interventionMyocardial infarctionHolter ECG monitoringMyocardial infarct sizeSingle photon emissionMultivariable adjustmentClinical outcomesRisk factorsClinical trialsNoninvasive biomarkersCore laboratoryMechanistic correlatesMortalityECG monitoringInfarctionRecovery parametersST parametersInterventionOutcomes
2013
Comparison of Clinical Interpretation With Visual Assessment and Quantitative Coronary Angiography in Patients Undergoing Percutaneous Coronary Intervention in Contemporary Practice
Nallamothu BK, Spertus JA, Lansky AJ, Cohen DJ, Jones PG, Kureshi F, Dehmer GJ, Drozda JP, Walsh MN, Brush JE, Koenig GC, Waites TF, Gantt DS, Kichura G, Chazal RA, O’Brien P, Valentine CM, Rumsfeld JS, Reiber JH, Elmore JG, Krumholz RA, Weaver WD, Krumholz HM. Comparison of Clinical Interpretation With Visual Assessment and Quantitative Coronary Angiography in Patients Undergoing Percutaneous Coronary Intervention in Contemporary Practice. Circulation 2013, 127: 1793-1800. PMID: 23470859, PMCID: PMC3908681, DOI: 10.1161/circulationaha.113.001952.Peer-Reviewed Original ResearchConceptsQuantitative coronary angiographyPercent diameter stenosisPercutaneous coronary interventionDiameter stenosisCoronary interventionCoronary angiographyCoronary lesionsClinical interpretationAngiographic interpretationStenosis severityHigher percent diameter stenosisMedian percent diameter stenosisElective percutaneous coronary interventionMean differenceCoronary stenosis severityIntermediate lesionsUS hospitalsStenosisLesionsAngiographyPatientsInterventionSeverityVisual assessmentSuch findings
2012
Advances in the hospital management of patients following an out of hospital cardiac arrest
Nolan JP, Lyon RM, Sasson C, Rossetti AO, Lansky AJ, Fox KA, Meier P. Advances in the hospital management of patients following an out of hospital cardiac arrest. Heart 2012, 98: 1201. PMID: 22649095, DOI: 10.1136/heartjnl-2011-301293.Peer-Reviewed Original ResearchMeSH KeywordsCardiology Service, HospitalCardiopulmonary ResuscitationCoronary AngiographyCritical PathwaysDelivery of Health Care, IntegratedEmergency Medical ServicesHealth Services Needs and DemandHumansHypothermia, InducedMonitoring, PhysiologicOut-of-Hospital Cardiac ArrestPatient Care TeamPrognosisTime FactorsConceptsHospital cardiac arrestCardiac arrestCoronary angiography/interventionCardiac arrest centersPost-resuscitation managementEmergency medicine physiciansCardiac outputArrest pathwaysHospital careTrauma careMedicine physiciansPrehospital careBetter outcomesSingle interventionPatient careDisappointing resultsCareMultidisciplinary approachHospital managementPatientsOutcomesOHCA treatmentInterventionArrestIntensivists
2005
Percutaneous Coronary Intervention and Adjunctive Pharmacotherapy in Women
Lansky AJ, Hochman JS, Ward PA, Mintz GS, Fabunmi R, Berger PB, New G, Grines CL, Pietras CG, Kern MJ, Ferrell M, Leon MB, Mehran R, White C, Mieres JH, Moses JW, Stone GW, Jacobs AK. Percutaneous Coronary Intervention and Adjunctive Pharmacotherapy in Women. Circulation 2005, 111: 940-953. PMID: 15687113, DOI: 10.1161/01.cir.0000155337.50423.c9.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary interventionAdjunctive pharmacotherapyHigh-risk acute coronary syndromesContemporary interventional therapyNonfatal ischemic complicationsAcute coronary syndromeAcute myocardial infarctionSex-specific dataCoronary syndromeIschemic complicationsMyocardial infarctionInterventional therapyWomenPharmacotherapyInterventionComplicationsInfarctionSyndromeTherapy
2004
Impact of anemia on outcomes of patients undergoing percutaneous coronary interventions
Nikolsky E, Mehran R, Aymong ED, Mintz GS, Lansky AJ, Lasic Z, Negoita M, Fahy M, Pocock SJ, Na Y, Krieger S, Moses JW, Stone GW, Leon MB, Dangas G. Impact of anemia on outcomes of patients undergoing percutaneous coronary interventions. The American Journal Of Cardiology 2004, 94: 1023-1027. PMID: 15476616, DOI: 10.1016/j.amjcard.2004.06.058.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary interventionMortality rateSmaller body mass indexImpact of anemiaCardiovascular risk factorsOutcomes of patientsCo-morbid conditionsBody mass indexHigh mortality rateWorld Health OrganizationConsecutive patientsBaseline hematocritMass indexPotential confoundersRisk factorsAnemiaPatientsHealth OrganizationSignificant predictorsInterventionHospitalizationConfoundersHigh frequencyHematocritPrognostic significance of cerebrovascular and peripheral arterial disease in patients having percutaneous coronary interventions
Nikolsky E, Mehran R, Dangas GD, Lasic Z, Mintz GS, Negoita M, Lansky AJ, Stone GW, Moussa I, Iyer S, Na Y, Moses JW, Leon MB. Prognostic significance of cerebrovascular and peripheral arterial disease in patients having percutaneous coronary interventions. The American Journal Of Cardiology 2004, 93: 1536-1539. PMID: 15194030, DOI: 10.1016/j.amjcard.2004.03.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAngioplasty, Balloon, CoronaryBody Mass IndexCase-Control StudiesCerebrovascular DisordersCoronary Artery DiseaseDiabetes ComplicationsFemaleHospital MortalityHumansKidney Failure, ChronicLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisPeripheral Vascular DiseasesPrognosisSaphenous VeinSex Factors
2003
Outcomes following Bail-Out abciximab administration during primary intervention in acute myocardial infarction (The CADILLAC Trial)
Ashby DT, Aymong EA, Tcheng JE, Grines CL, Cox DA, Mehran R, Garcia E, Griffin JJ, Guagliumi G, Stuckey T, Turco M, Lansky AJ, Stone GW. Outcomes following Bail-Out abciximab administration during primary intervention in acute myocardial infarction (The CADILLAC Trial). The American Journal Of Cardiology 2003, 92: 1091-1094. PMID: 14583362, DOI: 10.1016/j.amjcard.2003.06.005.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalCross-Over StudiesDrug Administration ScheduleFemaleFollow-Up StudiesHumansImmunoglobulin Fab FragmentsIntraoperative ComplicationsMaleMiddle AgedMyocardial InfarctionPlatelet Glycoprotein GPIIb-IIIa ComplexProspective StudiesTreatment FailureConceptsAcute myocardial infarctionMyocardial infarctionGlycoprotein IIb/IIIa receptor inhibitorsUnsuccessful primary percutaneous coronary interventionIIb/IIIa receptor inhibitorsMyocardial Infarction (TIMI) grade 3 flowPrimary percutaneous coronary interventionGrade 3 flowPercutaneous coronary interventionSuboptimal angioplasty resultsAbciximab administrationCADILLAC trialIschemic complicationsControl patientsCoronary interventionProcedural complicationsAngioplasty resultsReceptor inhibitorsPrimary interventionAbciximabPatientsComplicationsInfarctionLower ratesIntervention
2000
Mechanism of Lumen Enlargement During Intracoronary Stent Implantation
Ahmed J, Mintz G, Weissman N, Lansky A, Pichard A, Satler L, Kent K. Mechanism of Lumen Enlargement During Intracoronary Stent Implantation. Circulation 2000, 102: 7-10. PMID: 10880407, DOI: 10.1161/01.cir.102.1.7.Peer-Reviewed Original ResearchConceptsLumen enlargementReference segmentsExternal elastic membrane areaDistal reference segmentsNative coronary lesionsIntracoronary stent implantationIntravascular ultrasound analysisMean lumen areaExternal elastic membraneCoronary lesionsPlaque burdenPlaque embolizationStent implantationMultilink stentsProximal referenceDistal referenceIntravascular ultrasoundLesionsUltrasound analysisLumen areaPlaquesVolumetric analysisVessel expansionInterventionMedia area
1998
Heparin dosing in patients undergoing coronary intervention
Popma J, Prpic R, Lansky A, Piana R. Heparin dosing in patients undergoing coronary intervention. The American Journal Of Cardiology 1998, 82: 19p-24p. PMID: 9809888, DOI: 10.1016/s0002-9149(98)00759-0.Peer-Reviewed Original ResearchConceptsIIb/IIIa inhibitorsCoronary interventionHeparin therapyHemochron devicePlatelet glycoprotein IIb/IIIa inhibitorsGlycoprotein IIb/IIIa inhibitorsGP IIb/IIIa inhibitorsUncomplicated coronary interventionsWeight-adjusted heparinAntithrombotic regimenHemoTec deviceHeparin bolusHeparin dosingSufficient heparinHeparin administrationConventional heparinUnfractionated heparinSignificant thrombocytopeniaPatientsACT levelsHeparinLonger durationTarget ACTInterventionAnticoagulationLipid-Lowering Therapy After Coronary Revascularization: The Interventional Cardiologist’s Perspective 11This work was supported by the Cardiology Research Foundation, Washington, DC.
Lansky A, Popma J, Mintz G, Laird J, Saucedo J, Leon M. Lipid-Lowering Therapy After Coronary Revascularization: The Interventional Cardiologist’s Perspective 11This work was supported by the Cardiology Research Foundation, Washington, DC. The American Journal Of Cardiology 1998, 81: 55e-62e. PMID: 9551596, DOI: 10.1016/s0002-9149(98)00199-4.Peer-Reviewed Original ResearchConceptsCoronary eventsCoronary interventionCholesterol levelsAggressive lipid-lowering therapyCardiology Research FoundationLipid-lowering therapyTreatment of stenosisPatients' cholesterol levelsLipid-laden plaqueCoronary revascularizationCoronary atherosclerosisUnderlying diseaseRevascularization proceduresAtherosclerotic progressionCardiologist's practiceAdvanced lesionsCholesterol reductionPlaque accumulationIntravascular ultrasoundOwn carePatientsTherapyInterventionRevascularizationAtherectomy