2012
Safety and Efficacy of High- Versus Low-Dose Aspirin After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction The HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial
Yu J, Mehran R, Dangas GD, Claessen BE, Baber U, Xu K, Parise H, Fahy M, Lansky AJ, Witzenbichler B, Grines CL, Guagliumi G, Kornowski R, Wöhrle J, Dudek D, Weisz G, Stone GW. Safety and Efficacy of High- Versus Low-Dose Aspirin After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction The HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial. JACC Cardiovascular Interventions 2012, 5: 1231-1238. PMID: 23257371, DOI: 10.1016/j.jcin.2012.07.016.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionST-segment elevation myocardial infarctionLow-dose aspirinElevation myocardial infarctionHigh-dose aspirinPrimary PCIHORIZONS-AMI trialPercutaneous coronary interventionMyocardial infarctionMajor bleedingCoronary interventionIschemic target vessel revascularizationMajor adverse cardiovascular eventsCoronary artery bypass surgeryLong-term patient outcomesAdverse ischemic eventsAdverse cardiovascular eventsDose of aspirinTarget vessel revascularizationArtery bypass surgeryHistory of hypertensionPremature coronary diseaseLong-term outcomesIschemic benefitAspirin dose
2009
Prognostic Impact of Blood Transfusion After Primary Angioplasty for Acute Myocardial Infarction Analysis From the CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trial
Nikolsky E, Mehran R, Sadeghi HM, Grines CL, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Guagliumi G, Stuckey T, Turco M, Fahy M, Lansky AJ, Stone GW. Prognostic Impact of Blood Transfusion After Primary Angioplasty for Acute Myocardial Infarction Analysis From the CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trial. JACC Cardiovascular Interventions 2009, 2: 624-632. PMID: 19628185, DOI: 10.1016/j.jcin.2009.05.004.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAge FactorsAgedAnemiaAngioplasty, Balloon, CoronaryAntibodies, MonoclonalErythrocyte TransfusionFemaleHeart DiseasesHumansImmunoglobulin Fab FragmentsKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionOdds RatioPlatelet Aggregation InhibitorsProportional Hazards ModelsProspective StudiesRadiographyRecurrenceRisk AssessmentRisk FactorsSeverity of Illness IndexSex FactorsStrokeTime FactorsTreatment OutcomeConceptsPrimary percutaneous coronary interventionAcute myocardial infarctionPrimary PCIRBC transfusionCADILLAC trialClinical outcomesComposite major adverse cardiac eventsAcute Myocardial Infarction AnalysisMajor adverse cardiac eventsCoronary artery bypass surgeryRed blood cell transfusionMechanical reperfusion therapyAdverse cardiac eventsArtery bypass surgeryBlood cell transfusionTriple vessel diseasePercutaneous coronary interventionBaseline anemiaMajor bleedingTransfusion propensityCell transfusionIndex hospitalizationMultivariable adjustmentPrimary angioplastyReperfusion therapyTreatment of left main and multivessel disease in the drug-eluting stent era.
Ng VG, Lansky AJ. Treatment of left main and multivessel disease in the drug-eluting stent era. Reviews In Cardiovascular Medicine 2009, 10 Suppl 2: s24-33. PMID: 19898278, DOI: 10.3909/ricm10s20004.Peer-Reviewed Original ResearchConceptsDrug-eluting stentsBypass surgeryMultivessel coronary artery diseaseCoronary artery bypass surgeryDrug-eluting stent eraArtery bypass surgeryHigh-risk patientsPercutaneous coronary interventionCoronary artery diseaseSignificant survival advantageAlternative treatment modalityStandard of careBare metal stentsMultivessel diseaseRepeat revascularizationCoronary interventionArtery diseaseMedical managementStent eraBalloon angioplastyNonrandomized studyLabel useTreatment modalitiesInvasive strategyClinical trials
2007
An evaluation of fluoroscopy time and correlation with outcomes after percutaneous coronary intervention.
Nikolsky E, Pucelikova T, Mehran R, Balter S, Kaufman L, Fahy M, Lansky AJ, Leon MB, Moses JW, Stone GW, Dangas G. An evaluation of fluoroscopy time and correlation with outcomes after percutaneous coronary intervention. Journal Of Invasive Cardiology 2007, 19: 208-13. PMID: 17476034.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAngioplasty, Balloon, CoronaryCohort StudiesCoronary AngiographyCoronary Artery BypassCoronary DiseaseElectrocardiographyFemaleFluoroscopyFollow-Up StudiesHospital MortalityHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsProbabilityRetrospective StudiesRisk FactorsSensitivity and SpecificitySeverity of Illness IndexSurvival RateTime FactorsTreatment OutcomeConceptsCoronary artery bypass surgeryPercutaneous coronary interventionEmergent coronary artery bypass surgeryPrior coronary artery bypass surgeryProlonged fluoroscopy timeContrast-induced nephropathyPeripheral arterial diseaseFluoroscopy timeBaseline TIMICoronary interventionArterial diseaseComplexity of PCIType B2/C lesionsB2/C lesionsSevere lesion calcificationChronic renal insufficiencyArtery bypass surgeryShort-term prognosisMean fluoroscopy timeHospital deathHospital outcomesPeriprocedural complicationsRenal insufficiencyBypass surgeryLesion calcification
2000
Current perspectives on interventional treatment strategies in diabetic patients with coronary artery disease
Kornowski R, Lansky A. Current perspectives on interventional treatment strategies in diabetic patients with coronary artery disease. Catheterization And Cardiovascular Interventions 2000, 50: 245-254. PMID: 10842400, DOI: 10.1002/(sici)1522-726x(200006)50:2<245::aid-ccd22>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseCoronary interventionBypass surgeryArtery diseaseDiabetes mellitusDiabetic patientsClinical outcomesCoronary artery bypass surgeryDiffuse coronary artery diseaseCatheter-based coronary interventionsArtery bypass surgeryCoronary bypass surgeryInterventional treatment strategiesPercutaneous coronary interventionUse of antiplateletAtherosclerosis lesion progressionTarget vessel sizeAdjunctive pharmacologyMore restenosisMultivessel diseaseAtherosclerosis burdenCoronary atherosclerosisCoronary proceduresCoronary sitesAdjunctive pharmacotherapy