2022
Autoimmune hemolytic anemias and paroxysmal nocturnal hemoglobinuria
Tormey C, Siddon A. Autoimmune hemolytic anemias and paroxysmal nocturnal hemoglobinuria. 2022, 346-363. DOI: 10.1002/9781119719809.ch31.ChaptersParoxysmal nocturnal hemoglobinuriaAutoimmune hemolytic anemiaHemolytic anemiaNocturnal hemoglobinuriaMainstay of therapyChoice of therapyDegree of anemiaBone marrow dysfunctionTypes of symptomsBlood transfusionCold autoantibodiesMarrow dysfunctionRBC destructionPNH patientsPrimary disorderSevere hemolysisRare typeAnemiaAutoantibodiesSingle disorderMedical issuesUnique entityPatientsTherapyHemoglobinuria
2015
Impact of Molecular Clonality on Survival in Acute Myeloid Leukemia
Schulz W, Durant T, Rinder H, Tormey C, Torres R, Smith B, Hager K, Howe J, Siddon A. Impact of Molecular Clonality on Survival in Acute Myeloid Leukemia. Blood 2015, 126: 1385. DOI: 10.1182/blood.v126.23.1385.1385.Peer-Reviewed Original ResearchDe novo acute myeloid leukemiaNovo acute myeloid leukemiaAcute myeloid leukemiaMolecular clonalityAML patientsTumor heterogeneityMyeloid leukemiaNext-generation sequencingNormal-risk subjectsAdverse prognostic indicatorTime of diagnosisFurther prospective studiesLong-term outcomesFLT3-ITD mutationHigh-risk groupChoice of therapyFirst prospective evidenceLimited clinical utilityHigh-risk classificationEarly survivalStudy patientsOverall survivalPatient agePatient subsetsInitial diagnosis