1997
Expression and cytokine mediated modulation of adhesion/costimulation molecules ICAM‐1(CD54) and LFA‐3(CD58) in human ovarian cancer
SANTIN A, HERMONAT P, HISERODT J, CHIRIVA‐INTERNATI M, RAVAGGI A, WOODLIFF J, BARCLAY D, PECORELLI S, PARHAM G. Expression and cytokine mediated modulation of adhesion/costimulation molecules ICAM‐1(CD54) and LFA‐3(CD58) in human ovarian cancer. International Journal Of Gynecological Cancer 1997, 7: 273-278. DOI: 10.1046/j.1525-1438.1997.00453.x.Peer-Reviewed Original ResearchTumor cellsICAM-1Fresh tumorsFresh ovarian tumor cellsClonal T-cell proliferationICAM-1/LFAICAM-1 antigenT cell proliferationMolecules ICAM-1Human ovarian cancerHuman ovarian tumorsLFA-3 antigensOvarian tumor cellsSurface antigen expressionAntigen-independent conjugate formationLFA-3 moleculesT cell recognitionNumber of cytokinesCostimulation pathwayTumor vaccinesCostimulatory moleculesOvarian tumorsHelper cytokinesIL-2Cytokines TNF
1996
Differential Effects of High-Dose Gamma Irradiation on the Production of Transforming Growth Factor-Beta in Fresh and Established Human Ovarian Cancer
Santin A, Hiserodt J, DiSaia P, Pecorelli S, Granger G. Differential Effects of High-Dose Gamma Irradiation on the Production of Transforming Growth Factor-Beta in Fresh and Established Human Ovarian Cancer. Gynecologic Oncology 1996, 61: 403-408. PMID: 8641623, DOI: 10.1006/gyno.1996.0164.Peer-Reviewed Original ResearchConceptsOvarian carcinoma cell linesCarcinoma cell linesOvarian tumorsFresh tumorsCell linesHigh dosesImmunoinhibitory cytokinesTumor cellsFresh ovarian tumorsTGF-beta secretionTGF-beta productionCytokines TNF-alphaFresh tumor cellsWeak immunological responseFresh tumor samplesHuman ovarian cancerHuman ovarian carcinoma cell linesTNF-alphaOvarian cancerImmunological responseIFN-gammaCytokinesTumorsTumor samplesContinuous cell linesEffects of cytokines combined with high‐dose gamma irradiation on the expression of major histocompatibility complex molecules and intercellular adhesion molecule‐1 in human ovarian cancers
Santin A, Rose G, Hiserodt J, Fruehauf J, Eck L, Garcia R, Schranz V, Disaia P, Pecorelli S, Granger G. Effects of cytokines combined with high‐dose gamma irradiation on the expression of major histocompatibility complex molecules and intercellular adhesion molecule‐1 in human ovarian cancers. International Journal Of Cancer 1996, 65: 688-694. PMID: 8598323, DOI: 10.1002/(sici)1097-0215(19960301)65:5<688::aid-ijc21>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsMHC class 1TNF-alphaAntigen expressionIFN-gammaFresh tumorsOvarian cell linesTumor cellsIntercellular adhesion molecule-1Cell linesICAM-1 antigen expressionHuman ovarian cancer cell linesOvarian cancer cell linesMajor histocompatibility complex moleculesICAM-1 antigenCytokines TNF-alphaClass 1Adhesion molecule-1Human ovarian cancerHuman ovarian tumorsEffects of cytokinesHuman ovarian cell linesRemoval of cytokinesICAM-1 surfaceHistocompatibility complex moleculesCancer cell lines