2015
A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers
Worhunsky PD, Dager AD, Meda SA, Khadka S, Stevens MC, Austad CS, Raskin SA, Tennen H, Wood RM, Fallahi CR, Potenza MN, Pearlson GD. A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers. Neuropsychopharmacology 2015, 41: 1637-1647. PMID: 26514582, PMCID: PMC4832027, DOI: 10.1038/npp.2015.332.Peer-Reviewed Original ResearchConceptsAlcohol useYoung adult drinkersYoung adultsPreliminary prospective studyAdult drinkersExcessive alcohol useAlcohol use disorderFunctional network activityProspective studyUse disordersFunctional brain networksGo/No-Go taskNeurobiological alterationsDomain scoresGreater riskDaily drinksAddictive disordersDrinkersDrinking occasionsLongitudinal studyFronto-parietal circuitryBrain networks
2014
Functional magnetic resonance imaging (fMRI) response to alcohol pictures predicts subsequent transition to heavy drinking in college students
Dager AD, Anderson BM, Rosen R, Khadka S, Sawyer B, Jiantonio‐Kelly R, Austad CS, Raskin SA, Tennen H, Wood RM, Fallahi CR, Pearlson GD. Functional magnetic resonance imaging (fMRI) response to alcohol pictures predicts subsequent transition to heavy drinking in college students. Addiction 2014, 109: 585-595. PMID: 24304235, PMCID: PMC3951577, DOI: 10.1111/add.12437.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlcohol DrinkingAlcohol-Related DisordersAlcoholic BeveragesAlcoholismBinge DrinkingBrainBrain MappingCaudate NucleusCerebral CortexCuesFactor Analysis, StatisticalFemaleFunctional NeuroimagingGyrus CinguliHumansLongitudinal StudiesMagnetic Resonance ImagingMalePhotic StimulationPrefrontal CortexRisk FactorsStudentsUniversitiesYoung AdultConceptsHeavy drinkersAlcohol-related problemsBOLD responseFunctional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) responseBlood oxygen level-dependent (BOLD) responseLevel-dependent responsesSingle brain networkSubsequent heavy drinkingPictures of alcoholBaseline factorsRisk factorsModerate drinkersBilateral caudateAnterior cingulateGreater riskOrbitofrontal cortexHeavy drinkingYoung adultsDrinkersDrinking amountGroup differencesBaselineAlcohol cuesLongitudinal studyNeural responses