2023
Evidence for Reduced Sensory Precision and Increased Reliance on Priors in Hallucination-Prone Individuals in a General Population Sample
Benrimoh D, Fisher V, Seabury R, Sibarium E, Mourgues C, Chen D, Powers A. Evidence for Reduced Sensory Precision and Increased Reliance on Priors in Hallucination-Prone Individuals in a General Population Sample. Schizophrenia Bulletin 2023, 50: 349-362. PMID: 37830405, PMCID: PMC10919780, DOI: 10.1093/schbul/sbad136.Peer-Reviewed Original ResearchSensory evidenceSensory precisionHallucinatory experiencesHallucination severityCH rateHallucination-prone individualsIncoming sensory evidencePrior weightingLinguistic versionsGaussian filter modelNonlinguistic stimuliPerceptual inferencePerceptual statesPerceptual beliefsResponse confidenceAuditory informationTask behaviorGeneral population sampleOnline sampleAuditory hallucinationsGeneral population participantsStimuliPast resultsParticipantsTask
2020
Modeling perception and behavior in individuals at clinical high risk for psychosis: Support for the predictive processing framework
Kafadar E, Mittal VA, Strauss GP, Chapman HC, Ellman LM, Bansal S, Gold JM, Alderson-Day B, Evans S, Moffatt J, Silverstein SM, Walker EF, Woods SW, Corlett PR, Powers AR. Modeling perception and behavior in individuals at clinical high risk for psychosis: Support for the predictive processing framework. Schizophrenia Research 2020, 226: 167-175. PMID: 32593735, PMCID: PMC7774587, DOI: 10.1016/j.schres.2020.04.017.Peer-Reviewed Original ResearchConceptsClinical high riskCHR participantsDegraded speech stimuliPredictive processing frameworkUtility of interventionsSample of participantsPerceptual inferenceSensory evidencePsychotic spectrum disordersSpeech stimuliSpeech taskComputational underpinningsBehavioral tasksEfficacy of interventionsSpectrum disorderTarget tonesParticipants' performanceComputational modelingHigh riskPoor recognitionLatent factorsSuch tasksPrior beliefsTaskAppropriate risk stratificationS197. PAVLOVIAN CONDITIONED HALLUCINATIONS TASKS AND PSYCHOMETRIC THRESHOLDING IN ENRICHED ONLINE SAMPLE
Kafadar E, Lim C, Powers A. S197. PAVLOVIAN CONDITIONED HALLUCINATIONS TASKS AND PSYCHOMETRIC THRESHOLDING IN ENRICHED ONLINE SAMPLE. Schizophrenia Bulletin 2020, 46: s113-s114. PMCID: PMC7234405, DOI: 10.1093/schbul/sbaa031.263.Peer-Reviewed Original ResearchAuditory verbal hallucinationsEmergence of hallucinationsAuditory stimuliNeural signaturesVisual stimuliUnusual experiencesOnline sampleIncoming sensory evidencePavlovian conditioning taskPredictive coding frameworkSalient auditory stimuliPrior beliefsPerceptual inferenceSensory evidencePerceptual experienceConditioning taskBrain processesTask methodologyResponses of participantsSensory modalitiesVerbal hallucinationsPotential therapeutic targetTask consistHallucinatory experiencesDiagnosis of psychosis