2024
Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia
Bai H, Varsanik M, Thaxton C, Ohashi Y, Gonzalez L, Zhang W, Aoyagi Y, Kano M, Yatsula B, Li Z, Pocivavsek L, Dardik A. Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia. AJP Heart And Circulatory Physiology 2024, 326: h1446-h1461. PMID: 38578237, PMCID: PMC11380968, DOI: 10.1152/ajpheart.00054.2024.Peer-Reviewed Original ResearchConceptsEndothelial cell lossOutflow veinChronic kidney diseaseJuxta-anastomotic areaMouse AVF modelNeointimal hyperplasiaThrombus formationAcute thrombus formationCell lossHuman AVF maturationGene OntologyAVF maturationAVF patencyEarly thrombus formationArteriovenous fistulaC57BL/6 miceClinical failureWistar ratsEndothelial lossKidney diseaseImmune responseEndothelial cellsHyperplasiaMiceAVF
1999
Chronic in vitro shear stress stimulates endothelial cell retention on prosthetic vascular grafts and reduces subsequent in vivo neointimal thickness
Dardik A, Liu A, Ballermann B. Chronic in vitro shear stress stimulates endothelial cell retention on prosthetic vascular grafts and reduces subsequent in vivo neointimal thickness. Journal Of Vascular Surgery 1999, 29: 157-167. PMID: 9882800, DOI: 10.1016/s0741-5214(99)70357-5.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAnimalsBeta-GalactosidaseBlood Vessel ProsthesisCell AdhesionCells, CulturedEndothelium, VascularFemaleGenetic VectorsHemorheologyHemostasisIn Vitro TechniquesMicroscopy, Electron, ScanningPolyurethanesRatsRats, Inbred F344Stress, MechanicalThrombosisTransfectionTunica IntimaConceptsProsthetic vascular graftsNeointimal thicknessDyne/cm2 shear stressEndothelial cellsGraft thrombosisEndothelial cell monolayersEndothelial cell retentionHemostasis timeVascular graftsCell monolayersAlpha-smooth muscle actinFischer 344 rat aortaGraft patency rateReplication-deficient adenoviral vectorLuminal surfaceAortic interposition graftsImmediate graft thrombosisChronic shear stressCultured endothelial cellsGraft failureInterposition graftMacrophage infiltrationPatency ratesCell-seeded graftsRat aorta
1998
Successful delayed bilateral renal revascularization during active phase of Takayasu's arteritis
Dardik A, Ballermann B, Williams G. Successful delayed bilateral renal revascularization during active phase of Takayasu's arteritis. Journal Of Vascular Surgery 1998, 27: 552-554. PMID: 9546244, DOI: 10.1016/s0741-5214(98)70332-5.Peer-Reviewed Case Reports and Technical NotesConceptsBilateral renal revascularizationTakayasu arteritisRenal revascularizationRenal failureAnuric acute renal failureBilateral renal artery thrombosisActive-phase diseaseAggressive surgical revascularizationLonger ischemic timesRenal artery thrombosisAcute renal failureRenal arterial occlusionDevelopment of angiotensinSurgical revascularizationArtery thrombosisIschemic timeArterial occlusionArteritisRevascularizationPatientsExcellent resultsActive phaseThrombosisAngiotensinFailure