2024
Early thrombus formation is required of eccentric and heterogenous neointimal hyperplasia under disturbed flow
Bai H, Li Z, Zhang W, Thaxton C, Ohashi Y, Gonzalez L, Kano M, Yatsula B, Hwa J, Dardik A. Early thrombus formation is required of eccentric and heterogenous neointimal hyperplasia under disturbed flow. Journal Of Thrombosis And Haemostasis 2024 PMID: 39173878, DOI: 10.1016/j.jtha.2024.07.028.Peer-Reviewed Original ResearchEndothelial cell lossArteriovenous fistulaSmooth muscle cellsNeointimal hyperplasiaHeterogeneous neointimaCell lossThrombus formationMT/mG reporter miceHuman arteriovenous fistulaeInhibit neointimal hyperplasiaEarly thrombus formationAntiplatelet therapyC57BL/6 miceReporter miceAVF failureWistar ratsVenous systemJuxta-anastomotic areaMuscle cellsAnimal modelsVenous outflowEarly thrombusEndothelial cellsArterial inflowThrombus
2021
Chapter 13 Assessment of female sex in preclinical vascular models
Gao M, Gorecka J, Liu J, Dardik A. Chapter 13 Assessment of female sex in preclinical vascular models. 2021, 349-385. DOI: 10.1016/b978-0-12-822959-0.00005-5.ChaptersAneurysm formationSequelae of atherosclerosisArteriovenous fistula maturationPathophysiology of atherosclerosisCause of deathPositive vessel remodelingAtherosclerotic complicationsFistula maturationFemale sexVenous remodelingClinical trialsInflammatory responseSex hormonesCardiovascular diseaseDisease outcomePreclinical studiesAnimal modelsProtective roleAtherosclerosisLipid metabolismVessel remodelingFemale animalsOxidative stressNational InstituteNumber of participants