2022
Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty
Elsamadicy A, Koo A, Reeves B, Cross J, Hersh A, Hengartner A, Karhade A, Pennington Z, Akinduro O, Lo S, Gokaslan Z, Shin J, Mendel E, Sciubba D. Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty. Global Spine Journal 2022, 14: 1227-1237. PMID: 36318478, PMCID: PMC11289550, DOI: 10.1177/21925682221138053.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreSpinal column tumorsFrailty Risk ScoreInfluence of frailtySpinal column metastasesProportion of patientsRetrospective cohort studyNationwide Readmissions DatabaseRisk of readmissionMultivariate regression analysisIntermediate frailtyAdult patientsCohort studyIndependent predictorsSurgical interventionSpine surgeryReadmissionPatient readmissionRisk scorePatientsFrailtySurgeryCohortTumorsRegression analysisResponse: Implications of HFRS in Patients Undergoing Surgery for Primary Spinal Intradural/Cord Tumors
Elsamadicy A, Koo A, Sciubba D. Response: Implications of HFRS in Patients Undergoing Surgery for Primary Spinal Intradural/Cord Tumors. Global Spine Journal 2022, 13: 256-256. PMID: 36154494, PMCID: PMC9837522, DOI: 10.1177/21925682221129552.Peer-Reviewed Original Research
2020
Case Report: Suprasellar Pituitary Adenoma Presenting With Temporal Lobe Seizures
Hong CS, Gorrepati R, Kundishora AJ, Elsamadicy AA, Peter PR, Damisah EC, Manes RP, Omay SB. Case Report: Suprasellar Pituitary Adenoma Presenting With Temporal Lobe Seizures. Frontiers In Surgery 2020, 7: 598138. PMID: 33335912, PMCID: PMC7736041, DOI: 10.3389/fsurg.2020.598138.Peer-Reviewed Case Reports and Technical NotesPituitary macroadenomaTemporal lobeFurther seizure activityTemporal lobe seizuresYear old maleMass effectLeft temporal lobeSuprasellar pituitary adenomasEndocrine dysfunctionGeneralized seizuresSeizure activityPituitary pathologyPituitary adenomasMedical treatmentSeizuresEndoscopic endonasalMacroadenomasLobePatientsDysfunctionAdenomasSymptomsTumorsEndonasalPathologyRace and All-cause Mortality in Patients with a Primary Malignant or Nonmalignant Tumor of the Spinal Cord or Spinal Meninges
Elsamadicy A, Freedman I, Koo A, David W, Reeves B, Antonios J, Laurans M, Kolb L, Sciubba D. Race and All-cause Mortality in Patients with a Primary Malignant or Nonmalignant Tumor of the Spinal Cord or Spinal Meninges. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_203.Peer-Reviewed Original Research
2019
Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas
Harrison W, Elsamadicy AA, McMahon JT, Chagoya G, Sobel RA, McLendon RE, Adamson C. Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas. Journal Of Neuropathology & Experimental Neurology 2019, 78: 780-787. PMID: 31361005, DOI: 10.1093/jnen/nlz060.Peer-Reviewed Original ResearchConceptsFeatures of gangliogliomaGlioneuronal tumorInfratentorial gangliogliomasFourth ventricleRosette-forming glioneuronal tumorDistinct histologic entityUnusual adult casesPapillary glioneuronal tumorSurgical resectionSurgical excisionHistologic featuresAdult casesGlioneuronal neoplasmHistologic entityClinical significanceDysplastic gangliocytomaHistologic combinationCerebellar liponeurocytomaGangliogliomaUnusual caseTumorsRare occurrenceNeurocytomaDistinct findingsNeoplasms
2018
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors
Chongsathidkiet P, Jackson C, Koyama S, Loebel F, Cui X, Farber SH, Woroniecka K, Elsamadicy AA, Dechant CA, Kemeny HR, Sanchez-Perez L, Cheema TA, Souders NC, Herndon JE, Coumans JV, Everitt JI, Nahed BV, Sampson JH, Gunn MD, Martuza RL, Dranoff G, Curry WT, Fecci PE. Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors. Nature Medicine 2018, 24: 1459-1468. PMID: 30104766, PMCID: PMC6129206, DOI: 10.1038/s41591-018-0135-2.Peer-Reviewed Original ResearchConceptsT cell dysfunctionT cellsBone marrowCell dysfunctionT cell sequestrationTreatment-naïve subjectsT-cell lymphopeniaNaïve T cellsSetting of glioblastomaT cell surfaceCD4 countLymphoid organsImmune escapeCell lymphopeniaIntracranial tumorsCell sequestrationMurine modelIntracranial compartmentGlioblastomaMarrowDysfunctionTumorsCancerCellsCell surface