2024
Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group.
Tabor J, Dincer A, O'Brien J, Lei H, Vetsa S, Vasandani S, Jalal M, Yalcin K, Morales-Valero S, Marianayagam N, Alanya H, Elsamadicy A, Millares Chavez M, Aguilera S, Mishra-Gorur K, McGuone D, Fulbright R, Jin L, Erson-Omay E, Günel M, Moliterno J. Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group. Journal Of Neurosurgery 2024, 141: 664-672. PMID: 38518289, DOI: 10.3171/2024.1.jns231633.Peer-Reviewed Original ResearchBlack patientsSporadic meningiomasClinical outcomesGenomic profilingClinical behavior of meningiomasShorter progression-free survivalAnterior skull base tumorsClinical data of patientsHispanic patientsProgression-free survivalChromosome 1p deletionBehavior of meningiomasIncreased recurrence rateRate of recurrenceSkull base tumorsData of patientsSomatic driver mutationsNon-Black patientsShorter PFSOverall survivalAggressive meningiomasTRAF7 mutationsIntracranial meningiomasMeningioma resectionNon-black group
2021
Comprehensive Genomic Characterization of A Case of Granular Cell Tumor of the Posterior Pituitary Gland: A Case Report
Hong CS, Elsamadicy AA, Fisayo A, Inzucchi SE, Gopal PP, Vining EM, Erson-Omay EZ, Omay S. Comprehensive Genomic Characterization of A Case of Granular Cell Tumor of the Posterior Pituitary Gland: A Case Report. Frontiers In Endocrinology 2021, 12: 762095. PMID: 34925233, PMCID: PMC8671743, DOI: 10.3389/fendo.2021.762095.Peer-Reviewed Original ResearchConceptsGranular cell tumorPosterior pituitary glandCell tumorsPituitary glandComprehensive genomic characterizationWhole-exome sequencingImmune checkpoint inhibitorsPoor clinical outcomePituitary gland tumorsHistone deacetylase inhibitorsInstitutional review boardRadiographic compressionUnderwent resectionCheckpoint inhibitorsMedical therapyPituitary massClinical outcomesOptic nerveSignificant morbidityResidual diseaseCase reportCentral hypothyroidismPharmacologic agentsGland tumorsTherapeutic targeting
2017
Decompression in Adult Lumbar Deformity Surgery Is Associated With Increased Perioperative Complications but Favorable Long-Term Outcomes
Karikari IO, Bridwell KH, Elsamadicy AA, Lenke LG, Sugrue P, Bumpass D, Ahmad A, Gum J. Decompression in Adult Lumbar Deformity Surgery Is Associated With Increased Perioperative Complications but Favorable Long-Term Outcomes. Global Spine Journal 2017, 8: 110-113. PMID: 29662739, PMCID: PMC5898680, DOI: 10.1177/2192568217735509.Peer-Reviewed Original ResearchSymptomatic spinal stenosisLong-term outcomesPerioperative complicationsDecompression groupFormal decompressionClinical outcomesSpinal stenosisFavorable long-term clinical outcomesFavorable long-term outcomeLong-term clinical outcomesNRS back painNRS leg painRetrospective cohort studyDecompression patientsAdult patientsCohort studyComplication rateDeformity surgeryIncidental durotomyMean improvementLevels of fusionIliac fixationPatientsSRS domainsComplicationsEffect of Social Support and Marital Status on Perceived Surgical Effectiveness and 30-Day Hospital Readmission
Adogwa O, Elsamadicy AA, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Effect of Social Support and Marital Status on Perceived Surgical Effectiveness and 30-Day Hospital Readmission. Global Spine Journal 2017, 7: 774-779. PMID: 29238642, PMCID: PMC5721993, DOI: 10.1177/2192568217696696.Peer-Reviewed Original ResearchElective spine surgerySpine surgeryHospital stayReadmission ratesOutcome measuresLong-term clinical outcomesThirty-day readmission ratesLength of hospitalPostoperative complication rateRetrospective cohort reviewTime of surgeryMarital statusSocial supportMajor academic medical centerAcademic medical centerSignificant differencesBaseline characteristicsCohort reviewPatient demographicsComplication rateHospital readmissionClinical outcomesSurgical outcomesSurgical effectivenessMedical records
2016
Comparison of surgical outcomes after anterior cervical discectomy and fusion: does the intra-operative use of a microscope improve surgical outcomes
Adogwa O, Elsamadicy A, Reiser E, Ziegler C, Freischlag K, Cheng J, Bagley CA. Comparison of surgical outcomes after anterior cervical discectomy and fusion: does the intra-operative use of a microscope improve surgical outcomes. Journal Of Spine Surgery 2016, 2: 25-30. PMID: 27683692, PMCID: PMC5039832, DOI: 10.21037/jss.2016.01.04.Peer-Reviewed Original ResearchNeck Disability IndexVisual analog pain scaleSF-12 PCSSF-12 MCSAnterior cervical discectomyIntra-operative useCervical discectomyClinical outcomesSurgical outcomesVAS neck pain scoresLong-term clinical outcomesSuperior long-term outcomesPatient-reported outcome measuresStandard deviation durationSurgery-related outcomesVAS neck painAnalog pain scaleNeck pain scoresNerve root injuryLong-term outcomesClinical outcome dataMajor academic medical centerSimilar improvementsAcademic medical centerDisability Index
2015
Effects of Psoas Muscle Thickness on Outcomes of Lumbar Fusion Surgery
Verla T, Adogwa O, Elsamadicy A, Moreno JR, Farber H, Cheng J, Bagley CA. Effects of Psoas Muscle Thickness on Outcomes of Lumbar Fusion Surgery. World Neurosurgery 2015, 87: 283-289. PMID: 26619920, DOI: 10.1016/j.wneu.2015.11.022.Peer-Reviewed Original ResearchConceptsPsoas muscle thicknessLumbar fusion surgeryFusion surgeryMuscle thicknessPsoas muscleSpinal stabilizationVisual analog scale pain scoreHip flexor weaknessScale pain scoresPreoperative magnetic resonanceInterbody fusion surgeryLumbar intervertebral spaceSpecific clinical outcomesWarrants further investigationEarly ambulationPain scoresAdult patientsFlexor weaknessPostoperative rehabilitationRetrospective reviewClinical outcomesHospital recordsSurgical optionsLumbar pathologyFunctional outcomePretreatment of Anxiety Before Cervical Spine Surgery Improves Clinical Outcomes: A Prospective, Single-Institution Experience
Adogwa O, Elsamadicy AA, Cheng J, Bagley C. Pretreatment of Anxiety Before Cervical Spine Surgery Improves Clinical Outcomes: A Prospective, Single-Institution Experience. World Neurosurgery 2015, 88: 625-630. PMID: 26585724, DOI: 10.1016/j.wneu.2015.11.014.Peer-Reviewed Original ResearchConceptsNeck Disability IndexNeck pain scoresVisual analog scaleSpine surgeryPain scoresPostoperative painClinical outcomesControl cohortAffective disordersDuke University Medical CenterAnxiety disordersVAS neck painLower postoperative painSF-12 PCSAnterior cervical discectomyCervical spine pathologyCervical spine surgeryNerve root injurySF-12 MCSSingle institution experienceShort Form-12Clinical outcome dataPatient reported outcomesBoard-certified psychiatristUniversity Medical Center