2020
Diastolic stress test echocardiography in patients with hypertrophy cardiomyopathy: association with exercise capacity
Fava A, Mathias I, Alashi A, Saijo Y, Popovic Z, Thamilarasan M, Lever H, Desai M. Diastolic stress test echocardiography in patients with hypertrophy cardiomyopathy: association with exercise capacity. European Heart Journal 2020, 41: ehaa946.2087. DOI: 10.1093/ehjci/ehaa946.2087.Peer-Reviewed Original ResearchDiastolic dysfunctionExercise capacityLVOT gradientMaximal exerciseHCM patientsLate mitral inflow velocityLateral mitral annular velocityMitral E/eAbnormal diastolic responseSymptomatic HCM patientsAtrial volume indexReduced exercise capacityVentricular filling pressureMitral annular velocityMitral inflow velocityHypertrophic cardiomyopathy patientsLogistic regression analysisHypertrophy cardiomyopathyDiastolic responseMetabolic equivalentsCardiomyopathy patientsAnnular velocityFilling pressureFunctional capacityPatientsExercise capacity is associated with rest and peak-exercise left ventricular global longitudinal strain in patients with hypertrophic cardiomyopathy
Fava A, Alashi A, Saijo Y, Mathias I, Popovic Z, Thamilarasan M, Lever H, Desai M. Exercise capacity is associated with rest and peak-exercise left ventricular global longitudinal strain in patients with hypertrophic cardiomyopathy. European Heart Journal 2020, 41: ehaa946.0081. DOI: 10.1093/ehjci/ehaa946.0081.Peer-Reviewed Original ResearchLV-GLSHypertrophic cardiomyopathyExercise capacityHCM patientsVentricular global longitudinal strainGlobal myocardial strainSymptomatic HCM patientsReduced exercise capacitySubclinical cardiac dysfunctionSubclinical myocardial dysfunctionGlobal longitudinal strainLVOT gradientCardiac deteriorationExercise impairmentCardiac dysfunctionMyocardial dysfunctionMaximal exerciseExercise testExercise variablesClinical utilityFunctional capacityPatientsMyocardial strainLogistic regressionLongitudinal strain
2018
Exercise capacity in asymptomatic patients with significant primary mitral regurgitation: independent effect of global longitudinal left ventricular strain
Mentias A, Alashi A, Naji P, Gillinov AM, Rodriguez LL, Mihaljevic T, Suri RM, Grimm RA, Svensson LG, Griffin BP, Desai MY. Exercise capacity in asymptomatic patients with significant primary mitral regurgitation: independent effect of global longitudinal left ventricular strain. Cardiovascular Diagnosis And Therapy 2018, 8: 460-468. PMID: 30214861, PMCID: PMC6129839, DOI: 10.21037/cdt.2018.05.03.Peer-Reviewed Original ResearchRight ventricular systolic pressureLeft ventricular ejection fractionPrimary mitral regurgitationMean metabolic equivalentSignificant primary mitral regurgitationLV-GLSExercise capacityAsymptomatic patientsMitral regurgitationGlobal longitudinal left ventricular strainLeft ventricular global longitudinal strainMitral effective regurgitant orificeVentricular global longitudinal strainVentricular systolic pressureVentricular ejection fractionGlobal longitudinal strainFlail mitral leafletLeft ventricular strainEffective regurgitant orificeVelocity vector imagingVentricular strainEjection fractionIndependent predictorsSignificant arrhythmiasSystolic pressure