2022
Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest
Beekman R, Crawford A, Mazurek MH, Prabhat AM, Chavva IR, Parasuram N, Kim N, Kim JA, Petersen N, de Havenon A, Khosla A, Honiden S, Miller PE, Wira C, Daley J, Payabvash S, Greer DM, Gilmore EJ, Kimberly W, Sheth KN. Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest. Resuscitation 2022, 176: 150-158. PMID: 35562094, PMCID: PMC9746653, DOI: 10.1016/j.resuscitation.2022.05.002.Peer-Reviewed Original ResearchConceptsCardiac arrestBrain injuryHypoxic-ischemic brain injuryAdverse neurological outcomesIschemic brain injurySingle-center studyBrain magnetic resonanceBrain injury severityBoard-certified neuroradiologistsLow-field MRIFLAIR signal intensityNeurological outcomeCA patientsIll patientsMRI findingsCA survivorsCenter studyMRI examinationsClinical careHigh riskInjury severityPatientsSignal intensityBedside monitoringMR imaging
2020
Adrenal Insufficiency
Khosla A, Ahasic A. Adrenal Insufficiency. 2020, 417-421. DOI: 10.1007/978-3-030-26710-0_54.Peer-Reviewed Original ResearchCritical illness-related corticosteroid insufficiencyAdrenal insufficiencyAdrenocorticotropic hormoneAcute critical illnessRelative adrenal insufficiencyGlucocorticoid replacement therapyCause of shockMainstay of treatmentPrimary adrenal insufficiencyExogenous adrenocorticotropic hormoneCorticosteroid insufficiencyMineralocorticoid replacementCritical illnessSupportive careFluid resuscitationHypothalamic disorderIll patientsACTH levelsReplacement therapySalt repletionSerum cortisolCortisol levelsInsufficiencyPatientsEtiologyCritical Illness Related Corticosteroid Insufficiency (CIRCI)
Khosla A, Ahasic A. Critical Illness Related Corticosteroid Insufficiency (CIRCI). 2020, 423-428. DOI: 10.1007/978-3-030-26710-0_55.Peer-Reviewed Original ResearchCritical illness related corticosteroid insufficiencyHypothalamic pituitary adrenal axisCorticosteroid insufficiencyCritical illness-related corticosteroid insufficiencyACTH stimulation testingRelative adrenal insufficiencyCardiopulmonary bypass surgeryIntensive care unitPituitary-adrenal axisRefractory hypotensionAdrenal insufficiencyBypass surgeryCritical illnessSystemic inflammationIll patientsSeptic shockCare unitGlucocorticoid activityStimulation testingAdrenal axisCardiac arrestConventional therapyPatient's illnessSuch illnessesCortisol measurements