2023
Malpractice Litigation Related to Diagnosis and Treatment of Intracranial Aneurysms
Khan A, Khunte M, Wu X, Bajaj S, Payabvash S, Wintermark M, Matouk C, Seidenwurm D, Gandhi D, Parizel P, Mezrich J, Malhotra A. Malpractice Litigation Related to Diagnosis and Treatment of Intracranial Aneurysms. American Journal Of Neuroradiology 2023, 44: 460-466. PMID: 36997286, PMCID: PMC10084911, DOI: 10.3174/ajnr.a7828.Peer-Reviewed Original Research
2022
Optimizing Small, Low-Risk, Unruptured Intracranial Aneurysm Treatment Using Game Theory
Boltyenkov A, Wang J, Malhotra A, Katz J, Dehdashti A, White T, Martinez G, Pandya A, Sanelli P. Optimizing Small, Low-Risk, Unruptured Intracranial Aneurysm Treatment Using Game Theory. American Journal Of Neuroradiology 2022, 43: 176-180. PMID: 35027349, PMCID: PMC8985687, DOI: 10.3174/ajnr.a7392.Peer-Reviewed Original ResearchMeSH KeywordsAneurysm, RupturedConservative TreatmentEndovascular ProceduresGame TheoryHumansIntracranial AneurysmPhysicians
2020
Reduced 2-year aneurysm retreatment and costs among patients treated with flow diversion versus non-flow diversion embolization: A Premier Healthcare Database retrospective cohort study
Grandhi R, Karsy M, Taussky P, Ricker CN, Malhotra A. Reduced 2-year aneurysm retreatment and costs among patients treated with flow diversion versus non-flow diversion embolization: A Premier Healthcare Database retrospective cohort study. PLOS ONE 2020, 15: e0234478. PMID: 32555657, PMCID: PMC7302520, DOI: 10.1371/journal.pone.0234478.Peer-Reviewed Original ResearchConceptsPipeline Embolization DeviceEndovascular treatmentRetreatment ratePS matchingIntracranial aneurysmsRetrospective cohort studyRate of readmissionEmergency department visitsLength of stayLower retreatment rateInitial treatment costsUnruptured intracranial aneurysmsPropensity-score matchingTime of treatmentCumulative followCohort studyReadmission costsDepartment visitsPatient subgroupsPED placementCase selection biasSame hospitalAneurysm retreatmentEmbolization DevicePatientsManagement of Small, Unruptured Intracranial Aneurysms
Malhotra A, Wu X, Gandhi D, Sanelli P, Matouk CC. Management of Small, Unruptured Intracranial Aneurysms. World Neurosurgery 2020, 135: 379-380. PMID: 32143243, DOI: 10.1016/j.wneu.2019.12.139.Peer-Reviewed Original Research
2019
Vessel wall magnetic resonance imaging in intracranial aneurysms: Principles and emerging clinical applications
Santarosa C, Cord B, Koo A, Bhogal P, Malhotra A, Payabvash S, Minja FJ, Matouk CC. Vessel wall magnetic resonance imaging in intracranial aneurysms: Principles and emerging clinical applications. Interventional Neuroradiology 2019, 26: 135-146. PMID: 31818175, PMCID: PMC7507220, DOI: 10.1177/1591019919891297.Peer-Reviewed Original ResearchScreening for Intracranial Aneurysms in Patients with Thoracic Aortic Aneurysms
Malhotra A, Seifert K, Wu X, Matouk C, Elefteriades JA. Screening for Intracranial Aneurysms in Patients with Thoracic Aortic Aneurysms. Cerebrovascular Diseases 2019, 47: 253-259. PMID: 31412341, DOI: 10.1159/000501194.Peer-Reviewed Original ResearchConceptsPrevalence of IAsThoracic aortic aneurysmIntracranial aneurysmsRetrospective studyAortic aneurysmRisk factorsPrevious retrospective studySignificant risk factorsPotential risk factorsMagnetic resonance angiogramStudent's t-testPatient demographicsUnivariate analysisHigh prevalenceLarge cohortGeneral populationPatientsAneurysmsPrevalenceCategorical variablesΧ2 testHypertensionT-testContinuous variablesIA locationCost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchMeSH KeywordsAdultComputed Tomography AngiographyCost-Benefit AnalysisDisease ManagementFemaleFollow-Up StudiesHumansIntracranial AneurysmMaleMiddle AgedUnited StatesConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomesManagement of Unruptured Intracranial Aneurysms in Older Adults: A Cost-effectiveness Analysis.
Malhotra A, Wu X, Forman HP, Matouk CC, Hughes DR, Gandhi D, Sanelli P. Management of Unruptured Intracranial Aneurysms in Older Adults: A Cost-effectiveness Analysis. Radiology 2019, 291: 411-417. PMID: 30888931, DOI: 10.1148/radiol.2019182353.Peer-Reviewed Original ResearchMR Angiography Screening and Surveillance for Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Cost-effectiveness Analysis
Malhotra A, Wu X, Matouk CC, Forman HP, Gandhi D, Sanelli P. MR Angiography Screening and Surveillance for Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Cost-effectiveness Analysis. Radiology 2019, 291: 400-408. PMID: 30777807, DOI: 10.1148/radiol.2019181399.Peer-Reviewed Original ResearchComparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm.
Malhotra A, Wu X, Miller T, Matouk CC, Sanelli P, Gandhi D. Comparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm. Journal Of Neurosurgery 2019, 132: 42-50. PMID: 30641830, DOI: 10.3171/2018.8.jns181080.Peer-Reviewed Original ResearchConceptsPipeline Embolization DeviceStent-assisted coilingRetreatment rateSmall unruptured aneurysmsComparative effectiveness analysisProbabilistic sensitivity analysesUnruptured aneurysmsEndovascular coilingHealth benefitsUse of PEDHigher health benefitsRate of recurrenceFavorable treatment strategyDecision-analytical studyStent-assisted techniquePED placementTreatment modalitiesEffectiveness analysisTreatment strategiesSmall aneurysmsEmbolization DeviceSimple coilingOutcome riskAneurysmsRetreatment
2018
Letter to the Editor Regarding “Preoperative Digital Subtraction Angiography in Incidental Unruptured Intracranial Aneurysms”
Malhotra A, Wu X, Tu L, Seifert K. Letter to the Editor Regarding “Preoperative Digital Subtraction Angiography in Incidental Unruptured Intracranial Aneurysms”. Clinical Neuroradiology 2018, 28: 437-437. PMID: 29951809, DOI: 10.1007/s00062-018-0700-6.Peer-Reviewed Original ResearchThe Patient with Thunderclap Headache
Malhotra A, Wu X, Gandhi D, Sanelli P. The Patient with Thunderclap Headache. Neuroimaging Clinics Of North America 2018, 28: 335-351. PMID: 30007749, DOI: 10.1016/j.nic.2018.03.002.Peer-Reviewed Original ResearchMeSH KeywordsAneurysm, RupturedHeadache Disorders, PrimaryHumansIntracranial AneurysmSubarachnoid HemorrhageTomography, X-Ray ComputedConceptsSubarachnoid hemorrhageThunderclap headacheCT angiographyConvexity subarachnoid hemorrhageHours of onsetPerimesencephalic subarachnoid hemorrhageNegative CT angiographyPattern of bloodCommon presentationEmergency departmentEarly diagnosisPatientsMR imagingMultiple causesHeadacheAngiographyHemorrhageBloodDiagnosisCTManagement of Small Unruptured Intracranial Aneurysms: A Survey of Neuroradiologists
Malhotra A, Wu X, Geng B, Hersey D, Gandhi D, Sanelli P. Management of Small Unruptured Intracranial Aneurysms: A Survey of Neuroradiologists. American Journal Of Neuroradiology 2018, 39: 875-880. PMID: 29650787, PMCID: PMC7410652, DOI: 10.3174/ajnr.a5631.Peer-Reviewed Original ResearchGrowth and Rupture Risk of Small Unruptured Intracranial Aneurysms.
Malhotra A, Wu X. Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms. Annals Of Internal Medicine 2018, 168: 159. PMID: 29335726, DOI: 10.7326/l17-0524.Peer-Reviewed Original ResearchManagement of Tiny Unruptured Intracranial Aneurysms: A Comparative Effectiveness Analysis
Malhotra A, Wu X, Forman HP, Matouk CC, Gandhi D, Sanelli P. Management of Tiny Unruptured Intracranial Aneurysms: A Comparative Effectiveness Analysis. JAMA Neurology 2018, 75: 27-34. PMID: 29159405, PMCID: PMC5833486, DOI: 10.1001/jamaneurol.2017.3232.Peer-Reviewed Original ResearchConceptsUnruptured intracranial aneurysmsComparative effectiveness analysisPreventive treatmentAdult patientsAnnual riskIntracranial aneurysmsHealth benefitsFollow-up imagingCurrent clinical practiceBetter health outcomesRisk of ruptureImaging surveillanceTiny aneurysmsMean ageSubarachnoid hemorrhageRoutine treatmentIncidental detectionEffectiveness analysisClinical studiesMAIN OUTCOMEHigh riskGeneral populationPatientsPubMed searchClinical practice
2017
Letter to the Editor regarding “Comparison of Rates of Growth between Unruptured and Ruptured Aneurysms Using Magnetic Resonance Angiography”
Malhotra A, Wu X, Tu LH, Seifert K. Letter to the Editor regarding “Comparison of Rates of Growth between Unruptured and Ruptured Aneurysms Using Magnetic Resonance Angiography”. Journal Of Stroke And Cerebrovascular Diseases 2017, 27: 821. PMID: 29269222, DOI: 10.1016/j.jstrokecerebrovasdis.2017.11.020.Peer-Reviewed Original ResearchLetter to the Editor Regarding “Growth of Untreated Unruptured Small-sized Aneurysms (<7 mm): Incidence and Related Factors”
Malhotra A, Wu X, Tu L, Seifert K. Letter to the Editor Regarding “Growth of Untreated Unruptured Small-sized Aneurysms (<7 mm): Incidence and Related Factors”. Clinical Neuroradiology 2017, 28: 307-308. PMID: 29052743, DOI: 10.1007/s00062-017-0638-0.Peer-Reviewed Original ResearchGrowth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review.
Malhotra A, Wu X, Forman HP, Grossetta Nardini HK, Matouk CC, Gandhi D, Moore C, Sanelli P. Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review. Annals Of Internal Medicine 2017, 167: 26-33. PMID: 28586893, DOI: 10.7326/m17-0246.Peer-Reviewed Original Research
2016
Regarding “Computer-Assisted Detection of Cerebral Aneurysms in MR Angiography in a Routine Image-Reading Environment: Effects on Diagnosis by Radiologists”
Wu X, Kalra VB, Durand D, Liu RC, Malhotra A. Regarding “Computer-Assisted Detection of Cerebral Aneurysms in MR Angiography in a Routine Image-Reading Environment: Effects on Diagnosis by Radiologists”. American Journal Of Neuroradiology 2016, 37: e80-e80. PMID: 27561835, PMCID: PMC7963866, DOI: 10.3174/ajnr.a4926.Peer-Reviewed Original ResearchRegarding “Cerebral Angiography for Evaluation of Patients with CT Angiogram-Negative Subarachnoid Hemorrhage: An 11-Year Experience”
Wu X, Kalra VB, Forman HP, Matouk CC, Mongelluzzo G, Liu R, Malhotra A. Regarding “Cerebral Angiography for Evaluation of Patients with CT Angiogram-Negative Subarachnoid Hemorrhage: An 11-Year Experience”. American Journal Of Neuroradiology 2016, 37: e52-e53. PMID: 27056430, PMCID: PMC7963535, DOI: 10.3174/ajnr.a4794.Peer-Reviewed Original Research