2024
Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaComputed Tomography AngiographyDiffusion Magnetic Resonance ImagingFemaleHumansIschemic StrokeMaleMiddle AgedRetrospective StudiesROC CurveStrokeConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohort
2023
Clinical implications of Peri-hematomal edema microperfusion fraction in intracerebral hemorrhage intravoxel incoherent motion imaging – A pilot study
Abou Karam G, Tharmaseelan H, Aboian M, Malhotra A, Gilmore E, Falcone G, de Havenon A, Sheth K, Payabvash S. Clinical implications of Peri-hematomal edema microperfusion fraction in intracerebral hemorrhage intravoxel incoherent motion imaging – A pilot study. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107375. PMID: 37738914, PMCID: PMC10591892, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107375.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain EdemaBrain InjuriesBrain NeoplasmsCerebral HemorrhageDiffusion Magnetic Resonance ImagingEdemaHematomaHumansMiddle AgedPilot ProjectsConceptsModified Rankin ScaleSecondary brain injuryIntracerebral hemorrhagePerihematomal edemaSubacute intracerebral hemorrhageIntravoxel incoherent motion imagingAdmission NIHSSBrain injuryMedian baseline National InstitutesPilot studyBaseline National InstitutesHealth Stroke ScalePerfusion fractionSupratentorial intracerebral hemorrhageIVIM metricsIncoherent motion imagingStroke ScaleNeuroprotective therapiesParenchymal injuryRankin ScaleRisk patientsConsecutive patientsUnivariable analysisPoor outcomeICH volume
2022
Brain injury patterns in hypoxic ischemic encephalopathy of term neonates
Bobba PS, Malhotra A, Sheth KN, Taylor SN, Ment LR, Payabvash S. Brain injury patterns in hypoxic ischemic encephalopathy of term neonates. Journal Of Neuroimaging 2022, 33: 79-84. PMID: 36164277, DOI: 10.1111/jon.13052.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain InjuriesDiffusion Magnetic Resonance ImagingHumansHypoxia-Ischemia, BrainInfant, NewbornInfarctionMagnetic Resonance ImagingConceptsSevere hypoxic-ischemic encephalopathyHypoxic-ischemic encephalopathyHypoxic-ischemic lesionsSeverity of HIEModerate hypoxic-ischemic encephalopathyTerm neonatesIschemic lesionsDiffusion-weighted imagingBasal gangliaDiagnosis of HIESeverity categoriesBrain injury patternsDeep white matterMRI diffusion-weighted imagingT2-weighted imagesPresence of lesionsVoxel-wise analysisRespiration (APGAR) scoreInfarct volumeStandard brain spaceIschemic encephalopathyInjury patternsBrain injuryLentiform nucleusLesion volume
2019
Differentiation of lymphomatous, metastatic, and non-malignant lymphadenopathy in the neck with quantitative diffusion-weighted imaging: systematic review and meta-analysis
Payabvash S, Brackett A, Forghani R, Malhotra A. Differentiation of lymphomatous, metastatic, and non-malignant lymphadenopathy in the neck with quantitative diffusion-weighted imaging: systematic review and meta-analysis. Neuroradiology 2019, 61: 897-910. PMID: 31175398, DOI: 10.1007/s00234-019-02236-7.Peer-Reviewed Original ResearchMeSH KeywordsDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingHead and Neck NeoplasmsHumansLymphadenopathyLymphatic MetastasisConceptsCervical lymph nodesAverage apparent diffusion coefficientStandardized mean differenceLymph nodesNon-malignant nodesDiagnostic odds ratioCervical lymphadenopathySubgroup analysisADC thresholdSystematic reviewSuspicious cervical lymph nodesUnknown primary cancer siteMean differenceNon-malignant lymphadenopathyCochrane Central RegisterNeck lymph nodesPrimary cancer siteConfidence intervalsSROC AUCRandom-effects modelComprehensive literature searchAverage ADC valueDiffusion-weighted imagingQuantitative diffusion-weighted imagingCentral RegisterQuantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis
Payabvash S, Chan A, Maralani P, Malhotra A. Quantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis. The Neuroradiology Journal 2019, 32: 232-240. PMID: 31084347, PMCID: PMC6639646, DOI: 10.1177/1971400919849808.Peer-Reviewed Original ResearchMeSH KeywordsDiffusion Magnetic Resonance ImagingEarly Detection of CancerFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPapillomaviridaePapillomavirus InfectionsSquamous Cell Carcinoma of Head and NeckConceptsNeck squamous cell carcinomaDiffusion-weighted imagingHPV-positive HNSCCSquamous cell carcinomaHPV-negative HNSCCPrimary tumor lesionsStandardized mean differenceQuantitative diffusion magnetic resonancePrimary lesionHPV statusTumor lesionsAverage ADCDiffusion magnetic resonanceMean differenceHiggins' inconsistency indexHuman papillomavirus (HPV) statusHuman papillomavirus infectionApparent diffusion coefficient (ADC) valuesRandom-effects modelNoninvasive imaging biomarkerComprehensive literature searchAverage ADC valueEcho-planar diffusion-weighted imagingFixed-effects modelPapillomavirus infection
2018
Grading of oligodendroglial tumors of the brain with apparent diffusion coefficient, magnetic resonance spectroscopy, and dynamic susceptibility contrast imaging
Naveed MA, Goyal P, Malhotra A, Liu X, Gupta S, Mangla M, Mangla R. Grading of oligodendroglial tumors of the brain with apparent diffusion coefficient, magnetic resonance spectroscopy, and dynamic susceptibility contrast imaging. The Neuroradiology Journal 2018, 31: 379-385. PMID: 29469659, PMCID: PMC6111423, DOI: 10.1177/1971400918757217.Peer-Reviewed Original Research
2017
Regarding “Uremic Encephalopathy: MR Imaging Findings and Clinical Correlation”
Das N, Wu X, Malhotra A. Regarding “Uremic Encephalopathy: MR Imaging Findings and Clinical Correlation”. American Journal Of Neuroradiology 2017, 38: e23-e24. PMID: 28082265, PMCID: PMC7959986, DOI: 10.3174/ajnr.a5058.Commentaries, Editorials and Letters