BRAF Mutation is Associated with an Improved Survival in Glioma—a Systematic Review and Meta-analysis
Vuong H, Altibi A, Duong U, Ngo H, Pham T, Fung K, Hassell L. BRAF Mutation is Associated with an Improved Survival in Glioma—a Systematic Review and Meta-analysis. Molecular Neurobiology 2017, 55: 3718-3724. PMID: 28534272, DOI: 10.1007/s12035-017-0599-y.Peer-Reviewed Original ResearchConceptsProgression-free survivalKaplan Meier curveOverall survivalBRAF V600EPrognostic valueBRAF mutationsGlioma patientsImproved survivalData of hazard ratioHazard ratioYoung adult gliomasImproved overall survivalMeta-analysisInverse variance methodLow grade gliomasVirtual Health LibraryPrognosis of glioma patientsRandom-effects modelPrognostic impactPrognostic factorsTumor gradeFavorable prognosisPatient ageAdult gliomasPooled HR