2021
Anticoagulation Is Associated with Increased Mortality in Splenic Injuries
Bhattacharya B, Becher RD, Schuster KM, Davis KA, Maung AA. Anticoagulation Is Associated with Increased Mortality in Splenic Injuries. Journal Of Surgical Research 2021, 266: 1-5. PMID: 33975026, DOI: 10.1016/j.jss.2021.04.002.Peer-Reviewed Original ResearchConceptsNon-ACS patientsSplenic injuryAC patientsMultivariable binary logistic regressionIndependent risk factorEffect of anticoagulationInjury Severity ScoreUnits of RBCsBinary logistic regressionHospital courseMedian LOSIncreased MortalitySeverity scoreRisk factorsWorse outcomesAnticoagulationSplenic surgeryAC groupPatientsHigh mortalityInjuryLogistic regressionMortalitySerious injuriesAngiography
2020
Choosing the Best Approach to Warfarin Reversal After Traumatic Intracranial Hemorrhage
Lumas SG, Hsiang W, Becher RD, Maung AA, Davis KA, Schuster KM. Choosing the Best Approach to Warfarin Reversal After Traumatic Intracranial Hemorrhage. Journal Of Surgical Research 2020, 260: 369-376. PMID: 33388533, DOI: 10.1016/j.jss.2020.12.004.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnticoagulantsBlood Coagulation FactorsCoagulantsConnecticutFemaleFollow-Up StudiesHospital CostsHumansIntracranial Hemorrhage, TraumaticLinear ModelsLogistic ModelsMaleMultivariate AnalysisPlasmaPractice Patterns, Physicians'Retrospective StudiesTomography, X-Ray ComputedTrauma CentersTreatment OutcomeWarfarinConceptsProthrombin complex concentrateFresh frozen plasmaTraumatic intracranial hemorrhageIntracranial hemorrhageWarfarin reversalReversal agentsUse of FFPAcademic level 1 trauma centerFollow-up computed tomography scanProgression of ICHFollow-up computed tomographyLevel 1 trauma centerComputed tomography scanTerms of mortalityElectronic medical recordsPreinjury warfarinElderly patientsHospital lengthInitial bleedICH progressionICH patientsMultivariable analysisRetrospective studyTrauma centerSurgical interventionThe effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study
Bhattacharya B, Askari R, Davis KA, Dorfman J, Eid AI, Elsharkawy AE, Kasotakis G, Mackey S, Odom S, Okafor BU, Rosenblatt M, Ruditsky A, Velmahos G, Maung AA. The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study. Injury 2020, 51: 1994-1998. PMID: 32482426, DOI: 10.1016/j.injury.2020.05.002.Peer-Reviewed Original ResearchConceptsNon-ACS patientsEffect of anticoagulationNon-operative managementSpleen injurySplenic injuryLiver injuryInitial non-operative managementSignificant differencesUse of anticoagulationBlood product transfusionMulticenter retrospective studyAC drugsMore PRBCsInjury gradeProduct transfusionCommon indicationAC patientsAtrial fibrillationRetrospective studyAnticoagulationSolid organsPatientsInjuryStudy periodLiver