2024
Impact of Poverty on Stroke Recurrence: A Population-Based Study.
Becker C, Sucharew H, Robinson D, Stamm B, Royan R, Nobel L, Stanton R, Jasne A, Woo D, De Los Rios La Rosa F, Mackey J, Ferioli S, Mistry E, Demel S, Haverbusch M, Coleman E, Slavin S, Walsh K, Star M, Flaherty M, Martini S, Kissela B, Kleindorfer D. Impact of Poverty on Stroke Recurrence: A Population-Based Study. Neurology 2024, 102: e209423. PMID: 38759136, PMCID: PMC11175648, DOI: 10.1212/wnl.0000000000209423.Peer-Reviewed Original ResearchConceptsNeighborhood socioeconomic statusPopulation-based studyIncident strokeCensus tractsSecondary analysisGreater Cincinnati/Northern Kentucky regionStroke recurrencePoisson regression modelsPoverty lineFederal poverty lineRecurrent strokeRecurrence riskVascular risk factorsResidents of poor neighborhoodsStudy periodAmerican Community SurveyNeighborhood povertySocioeconomic statusExcess riskStroke incidenceImpact of povertyPrimary exposureRelative riskStroke recurrence riskWhite individualsRacial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study
Aziz Y, Sucharew H, Stanton R, Alwell K, Ferioli S, Khatri P, Adeoye O, Flaherty M, Mackey J, La Rosa F, Martini S, Mistry E, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Ridha M, Ades L, Haverbusch M, Demel S, Woo D, Kissela B, Kleindorfer D. Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study. Journal Of The American Heart Association 2024, 13: e032645. PMID: 38700029, PMCID: PMC11179936, DOI: 10.1161/jaha.123.032645.Peer-Reviewed Original ResearchConceptsNational Institutes of Health Stroke Scale scoreWhite patientsStroke Scale scoreAcute ischemic strokeBlood pressureGreater Cincinnati/Northern Kentucky Stroke StudyDiastolic BPBlack patientsPopulation-based studyStudy epochInfluence clinical decision-makingScale scoreStroke risk factorsPresenting blood pressureIschemic strokeSubanalysis of patientsBody mass indexNational InstituteHistory of hypertensionMultivariate linear regressionClinical trial eligibilityAcute ischemic stroke presentingClinical decision-makingIschemic stroke presentingRacial disparities
2023
Changing Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis–Related Stroke, 2005–2015
Ridha M, Flaherty M, Aziz Y, Ades L, Alwell K, Khoury J, Woo D, Ferioli S, Adeoye O, Khatri P, De Los Rios La Rosa F, Mistry E, Demel S, Mackey J, Martini S, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Haverbusch M, Madsen T, Broderick J, Kissela B, Kleindorfer D. Changing Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis–Related Stroke, 2005–2015. Neurology 2023, 100: e1555-e1564. PMID: 36746635, PMCID: PMC10103121, DOI: 10.1212/wnl.0000000000206865.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidDemographyEndocarditisHumansHypertensionRetrospective StudiesRisk FactorsStrokeUnited StatesConceptsRisk factorsOpioid epidemicClinical characteristicsClinical featuresGreater Cincinnati/Northern Kentucky regionStudy periodRetrospective cohort studyRates of hypertensionIntravenous drug useIntravenous drug usersICD-10 codesCochran-Armitage testPerioperative strokeAcute strokeCohort studyDefinite endocarditisDuke criteriaHypertension prevalenceIschemic strokeYounger patientsStroke populationInfective endocarditisAtrial fibrillationEpidemiologic descriptionUnadjusted comparisons
2022
Racial Disparities in Stroke Recurrence
Robinson DJ, Stanton R, Sucharew H, Alwell K, Haverbusch M, De Los Rios La Rosa F, Ferioli S, Coleman E, Jasne A, Mackey J, Star M, Mistry EA, Demel S, Slavin S, Walsh K, Woo D, Kissela B, Kleindorfer DO. Racial Disparities in Stroke Recurrence. Neurology 2022, 99: e2464-e2473. PMID: 36041865, PMCID: PMC9728039, DOI: 10.1212/wnl.0000000000201225.Peer-Reviewed Original ResearchConceptsTraditional stroke risk factorsStroke risk factorsRisk factorsBlack raceRecurrent strokeStroke recurrenceRecurrence rateHigh riskGreater Cincinnati/Northern Kentucky populationBlack individualsStroke/TIA eventsRacial disparitiesStroke recurrence rateMultivariable survival analysisRisk of recurrenceKaplan-Meier estimatesSignificant racial disparitiesTIA eventsIncident strokeSmoking statusVentricular hypertrophyStroke casesRecurrenceSurvival analysisYounger age
2021
Expedited and Comprehensive Management of Low-Risk TIA Patients in the Emergency Department is Safe and Less Costly
Garg A, Maran I, Amin H, Vlieks K, Neuschatz K, Coppola A, Poskus K, Johnson J, Davis M, Minja F, Schindler J, Sansing LH, Malhotra A, Jasne AS, Sharma R. Expedited and Comprehensive Management of Low-Risk TIA Patients in the Emergency Department is Safe and Less Costly. Journal Of Stroke And Cerebrovascular Diseases 2021, 30: 106016. PMID: 34325273, DOI: 10.1016/j.jstrokecerebrovasdis.2021.106016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overClinical ProtocolsCost SavingsCost-Benefit AnalysisDecision Support TechniquesDelivery of Health Care, IntegratedEmergency Service, HospitalFeasibility StudiesFemaleHospital CostsHumansIschemic Attack, TransientLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeTriageConceptsLow-risk TIA patientsTransient ischemic attackTIA patientsEmergency roomAcademic comprehensive stroke centerSingle-center cohort studyPre-pathway groupComprehensive stroke centerClinical practice recommendationsLength of stayOutcomes of interestImpending strokeIschemic attackOutpatient echocardiogramRapid outpatientTIA admissionsEchocardiogram findingsEchocardiographic findingsStroke clinicCohort studyStroke centersNeurovascular eventsEmergency departmentFinal diagnosisHospital costs
2017
Contributors to the Excess Stroke Mortality in Rural Areas in the United States
Howard G, Kleindorfer DO, Cushman M, Long DL, Jasne A, Judd SE, Higginbotham JC, Howard VJ. Contributors to the Excess Stroke Mortality in Rural Areas in the United States. Stroke 2017, 48: 1773-1778. PMID: 28626048, PMCID: PMC5502731, DOI: 10.1161/strokeaha.117.017089.Peer-Reviewed Original ResearchConceptsHigh case fatalityCase fatalityStroke mortalityRisk factorsStroke incidenceSocioeconomic statusTraditional stroke risk factorsIncident stroke riskStroke risk factorsProportional hazards analysisHigher stroke incidenceStroke-free participantsUrban-rural statusHigher stroke mortalityLow socioeconomic statusRural-urban statusExcess stroke mortalityIncident strokeStroke riskREGARDS studyHigh prevalenceHigh incidenceRural areasLogistic regressionSmall rural town