Results of a study examining the use of onabotulinumtoxinA in pediatric patients with overactive bladder
Hoebeke P, Hittelman A, Jenkins B, Geib T, Titanji W, Bogaert G. Results of a study examining the use of onabotulinumtoxinA in pediatric patients with overactive bladder. Journal Of Pediatric Urology 2024, 20: 600.e1-600.e8. PMID: 38906707, DOI: 10.1016/j.jpurol.2024.04.019.Peer-Reviewed Original ResearchTreatment-emergent adverse eventsOveractive bladderPediatric patientsUrinary retentionUI episodesPrimary endpointTreatment of overactive bladderResponse rateUrinary incontinence (UIFrequency of UI episodesMultiple-dose studyNumerically greater reductionsLack of approved treatmentsTreatment cycles 1Urinary tract infectionBaseline to weekTreat overactive bladderTreatment response ratesTreatment cycle 2Dose armAnticholinergic therapyDouble-blindPlacebo armOnabotulinumtoxinA injectionsTract infections