2022
Association Between Hypertensive Disorders of Pregnancy and Dementia: a Systematic Review and Meta-Analysis
Schliep K, Mclean H, Yan B, Qeadan F, Theilen L, de Havenon A, Majersik J, Østbye T, Sharma S, Varner M. Association Between Hypertensive Disorders of Pregnancy and Dementia: a Systematic Review and Meta-Analysis. Hypertension 2022, 80: 257-267. PMID: 36345823, PMCID: PMC9851987, DOI: 10.1161/hypertensionaha.122.19399.Peer-Reviewed Original ResearchConceptsTypes of HDPCause dementiaVascular dementiaDementia subtypesHypertensive disordersRisk factorsObservational studyHigh riskVascular underpinningsPreeclampsia/eclampsiaImportant risk factorOnline electronic databasesGestational hypertensionHDP subtypesCohort studyUnspecified dementiaPooled analysisMaternal historyCardiovascular diseaseLater dementiaPrimary analysisElectronic databasesAlzheimer's diseaseMeta-AnalysisSystematic review
2021
Association of Preeclampsia With Incident Stroke in Later Life Among Women in the Framingham Heart Study
de Havenon A, Delic A, Stulberg E, Sheibani N, Stoddard G, Hanson H, Theilen L. Association of Preeclampsia With Incident Stroke in Later Life Among Women in the Framingham Heart Study. JAMA Network Open 2021, 4: e215077. PMID: 33900402, PMCID: PMC8076961, DOI: 10.1001/jamanetworkopen.2021.5077.Peer-Reviewed Original ResearchConceptsHistory of preeclampsiaVascular risk factorsIncident strokeRisk factorsFramingham Heart StudyMarginal structural modelsCohort studyStroke incidenceRelative riskHeart StudyLater lifeTime-varying covariatesMidlife vascular risk factorsPopulation-based cohort studyHigher diastolic blood pressureAbsence of preeclampsiaCholesterol-lowering medicationsDiastolic blood pressureAge 45 yearsAssociation of preeclampsiaBlood pressureMore pregnanciesStudy visitPreeclampsiaMAIN OUTCOME