2022
Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity
Schneider D, Honda T, Feldmann E, de Havenon A, Romano J, Nogueira R, Prabhakaran S, Mishra N, Beaman C, Hinman J, Commichau C, Callas P, Kaneko N, Morales J, Patel S, Sharma L, Kim S, Taatjes‐Sommer H, Liebeskind D. Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000201.Peer-Reviewed Original ResearchStroke/transient ischemic attackTransient ischemic attackRecent myocardial infarctionMyocardial infarctionPlatelet expressionFcγRIIa expressionNeurologic dysfunctionPlatelet reactivitySubsequent stroke/transient ischemic attacksSubsequent cardiovascular eventsEmbolic causesNonembolic causesPlatelet FcγRIIACardiovascular eventsIschemic attackIdentifies patientsIschemic strokeMethods PatientsDischarge diagnosisTreatment decisionsLower riskPatientsPlatelet activationFlow cytometryEmbolic
2021
Endothelial Shear Stress and Platelet FcγRIIa Expression in Intracranial Atherosclerotic Disease
Liebeskind DS, Hinman JD, Kaneko N, Kitajima H, Honda T, De Havenon AH, Feldmann E, Nogueira RG, Prabhakaran S, Romano JG, Callas PW, Schneider DJ. Endothelial Shear Stress and Platelet FcγRIIa Expression in Intracranial Atherosclerotic Disease. Frontiers In Neurology 2021, 12: 646309. PMID: 33716947, PMCID: PMC7947292, DOI: 10.3389/fneur.2021.646309.Peer-Reviewed Original ResearchIntracranial atherosclerotic diseaseEndothelial shear stressFcγRIIa expressionAtherosclerotic diseaseFcγRIIA receptorsArterial stenosisAnti-platelet medicationAnti-platelet strategiesPotent risk factorLocal pathophysiologyRecurrent strokeRisk factorsCardiovascular diseaseVascular remodelingIndividual patientsPlaque growthPlatelet activationElevated expressionDiseasePlatelet interactionClinical realmRecurrent eventsStenosisDifferential activationLuminal wall