2017
Do Tumor Necrosis Factor (TNF) Inhibitors Improve the Glycemic Control in Patients with Rheumatoid Arthritis and Concomitant Diabetes Mellitus?
Danve AS, Kulkarni S. Do Tumor Necrosis Factor (TNF) Inhibitors Improve the Glycemic Control in Patients with Rheumatoid Arthritis and Concomitant Diabetes Mellitus? American Journal Of Therapeutics 2017, 24: e347-e350. PMID: 26103543, DOI: 10.1097/mjt.0000000000000297.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisGlycemic controlTNF inhibitorsInsulin resistanceInsulin sensitivityTumor necrosis factor inhibitorsTumor necrosis factor alphaConcomitant rheumatoid arthritisInflammatory rheumatic diseasesNecrosis factor inhibitorsNecrosis factor alphaIncident diabetesDiabetes mellitusRheumatic diseasesFactor inhibitorsProinflammatory cytokinesFactor alphaPatientsMellitusArthritisInhibitorsDiabetesInflammationCytokinesDisease
2016
Tumor Necrosis Factor Inhibitors May Improve Glycemic Control in Patients Rheumatoid Arthritis and Concomitant Type 2 Diabetes Mellitus
Danve A, Division of Rheumatology Y, Sehra S, Jaykumar D, Kulkarni S, Instructor M, Internal Medicine N, Attending Physician M. Tumor Necrosis Factor Inhibitors May Improve Glycemic Control in Patients Rheumatoid Arthritis and Concomitant Type 2 Diabetes Mellitus. 2016, 1: 17-19. DOI: 10.17140/orhoj-1-106.Peer-Reviewed Original ResearchInsulin-sensitive tissuesInsulin receptor beta-subunitInsulin receptor substrate-1Inhibit insulin signalingReceptor beta-subunitInsulin-sensitive glucose transporterType 2 diabetes mellitusPhosphorylation cascadeTransmembrane signalingInsulin signalingTNF-aBeta subunitInsulin resistancePromote insulin resistanceGlucose transportConcomitant type 2 diabetes mellitusInsulin actionSensitive tissuesTumor necrosis factor-aInterleukin (IL)-6GLUT-4Factor AReceptor antibodiesLean ratsMetabolic syndrome