Tumor Necrosis Factor Inhibitors May Improve Glycemic Control in Patients Rheumatoid Arthritis and Concomitant Type 2 Diabetes Mellitus
Danve A, Division of Rheumatology Y, Sehra S, Jaykumar D, Kulkarni S, Instructor M, Internal Medicine N, Attending Physician M. Tumor Necrosis Factor Inhibitors May Improve Glycemic Control in Patients Rheumatoid Arthritis and Concomitant Type 2 Diabetes Mellitus. 2016, 1: 17-19. DOI: 10.17140/orhoj-1-106.Peer-Reviewed Original ResearchInsulin-sensitive tissuesInsulin receptor beta-subunitInsulin receptor substrate-1Inhibit insulin signalingReceptor beta-subunitInsulin-sensitive glucose transporterType 2 diabetes mellitusPhosphorylation cascadeTransmembrane signalingInsulin signalingTNF-aBeta subunitInsulin resistancePromote insulin resistanceGlucose transportConcomitant type 2 diabetes mellitusInsulin actionSensitive tissuesTumor necrosis factor-aInterleukin (IL)-6GLUT-4Factor AReceptor antibodiesLean ratsMetabolic syndrome