Vasopressin inactivation: Role of insulin-regulated aminopeptidase
Li DT, Habtemichael EN, Bogan JS. Vasopressin inactivation: Role of insulin-regulated aminopeptidase. Vitamins & Hormones 2019, 113: 101-128. PMID: 32138946, DOI: 10.1016/bs.vh.2019.08.017.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInsulin-regulated aminopeptidaseInsulin-responsive glucose transporterHuman placental leucine aminopeptidaseMetabolic syndromeInsulin resistanceVasopressin secretionUBX domainCoordinated regulationGenetic variationAbsence of insulinGLUT4 proteinGestational diabetes insipidusPotential pathophysiologic rolePhysiological importanceGlucose transporterCell surfaceProteolytic cleavageNovel insightsPlacental leucine aminopeptidaseRodent homologueVasopressinase activityLeucine aminopeptidasePathophysiologic mechanismsMuscle cellsPathophysiologic role