Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells
Song JE, Alves TC, Stutz B, Šestan-Peša M, Kilian N, Jin S, Diano S, Kibbey RG, Horvath TL. Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells. Metabolites 2021, 11: 322. PMID: 34069800, PMCID: PMC8157282, DOI: 10.3390/metabo11050322.Peer-Reviewed Original ResearchExogenous fatty acidsMitochondrial fissionMitochondrial fatty acid oxidationFatty acid oxidationFatty acid usageMitochondrial morphologyLipid dropletsAcid usageCarnitine palmitoyltransferase 1HeLa cellsDynamin-related proteinKey mitochondrial proteinsFatty acidsAcid oxidationMitochondrial proteinsLipid droplet accumulationMitochondrial dynamicsNovel functionLipid homeostasisHigh abundanceDirect roleDroplet accumulationMitochondriaFatty acid contentProtein