2001
Genomic and proteomic analysis of the myeloid differentiation program
Lian Z, Wang L, Yamaga S, Bonds W, Beazer-Barclay Y, Kluger Y, Gerstein M, Newburger P, Berliner N, Weissman S. Genomic and proteomic analysis of the myeloid differentiation program. Blood 2001, 98: 513-524. PMID: 11468144, DOI: 10.1182/blood.v98.3.513.Peer-Reviewed Original ResearchConceptsNew transcription factorMammalian cell typesMurine bone marrow cellsGene expression patternsDominant-negative retinoic acid receptorGene expression changesTranscription regulatory factorsMyeloid differentiation programRetinoic acid receptorsTranscription factorsProteomic analysisDifferentiation programArray hybridizationDifferential displayExpression patternsExpression changesPromyelocytic cell lineRegulatory factorsMyeloid differentiationLevels of mRNACell typesMolecular levelExtensive catalogueMicroM retinoic acidBone marrow cells
2000
Structural proteomics of an archaeon
Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort J, Booth V, Mackereth C, Saridakis V, Ekiel I, Kozlov G, Maxwell K, Wu N, McIntosh L, Gehring K, Kennedy M, Davidson A, Pai E, Gerstein M, Edwards A, Arrowsmith C. Structural proteomics of an archaeon. Nature Structural & Molecular Biology 2000, 7: 903-909. PMID: 11017201, DOI: 10.1038/82823.Peer-Reviewed Original ResearchConceptsStructural proteomicsHigh-throughput strategyFunctional genomicsNonmembrane proteinsPutative functionsBiochemical functionsSequence analysisMethanobacterium thermoautotrophicumProtein propertiesThroughput strategyX-ray crystallographicBiochemical methodsProteomicsStructural studiesCentral roleProteinStructural targetsNMR spectroscopic analysisProteomeArchaeonGenomicsThermoautotrophicumSequenceFunctionSpectroscopic analysisStructural proteomics: prospects for high throughput sample preparation
Christendat D, Yee A, Dharamsi A, Kluger Y, Gerstein M, Arrowsmith C, Edwards A. Structural proteomics: prospects for high throughput sample preparation. Progress In Biophysics And Molecular Biology 2000, 73: 339-345. PMID: 11063779, DOI: 10.1016/s0079-6107(00)00010-9.Peer-Reviewed Original Research