2025
Systematic review and meta-analysis of the genetics of peripheral arterial disease
Chaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. Journal Of Vascular Surgery 2025, 81: a13-a14. DOI: 10.1016/j.jvs.2024.10.063.Peer-Reviewed Original Research
2024
Presentation and patterns of reinterventions after revascularization in patients with premature peripheral arterial disease
Sivakumar A, Satam K, Wu Z, Alameddine D, Aboian E, Chaer R, Schermerhorn M, Moreira C, Guzman R, Chaar C. Presentation and patterns of reinterventions after revascularization in patients with premature peripheral arterial disease. European Journal Of Vascular And Endovascular Surgery 2024, 68: e77. DOI: 10.1016/j.ejvs.2024.11.007.Peer-Reviewed Original ResearchOpen and Endovascular Treatment of the Common Femoral Artery in a Tertiary Care Center
Wells N, Hundito A, Tuttle M, Alameddine D, Aboian E, Arhuidese I, Fischer U, Perez Lozada J, Guzman R, Ochoa Chaar C. Open and Endovascular Treatment of the Common Femoral Artery in a Tertiary Care Center. Journal Of Vascular Surgery 2024 PMID: 39442735, DOI: 10.1016/j.jvs.2024.10.027.Peer-Reviewed Original ResearchLower extremity revascularizationTreated with open surgeryPeripheral arterial diseaseCFA endarterectomyEndovascular therapyOpen surgeryEndovascular treatmentEndovascular lower extremity revascularizationTreated with endovascular therapyCompared to open surgeryAssociated with higher perioperative complicationsLower extremity revascularization proceduresPost-operative bleedingFemoral arteryImprove patient selectionKaplan-Meier analysisTertiary care centerTertiary-care centerLong-term outcomesEndovascular treatment of peripheral arterial diseaseLonger hospital lengthMALE-free survivalMultivariate logistic regressionTreatment of peripheral arterial diseaseCommon femoral arteryRuptured Complex Aortoiliac Aneurysm in an Elderly Patient With a Kidney Transplant Presenting With Sciatica.
Kostiuk V, Rodriguez P, Aboian E, Kuwayama D, Guzman R, Ochoa Chaar C. Ruptured Complex Aortoiliac Aneurysm in an Elderly Patient With a Kidney Transplant Presenting With Sciatica. Vascular And Endovascular Surgery 2024, 15385744241296220. PMID: 39438778, DOI: 10.1177/15385744241296220.Peer-Reviewed Original ResearchCommon iliac artery aneurysmsIliac artery aneurysmsAbdominal aortic aneurysmArtery aneurysmRenal artery originsKidney transplantationAortic aneurysmEndovascular repairAneurysm repairArtery originLeft common iliac artery aneurysmConcomitant abdominal aortic aneurysmNon-contrast CT scanComplex aneurysm anatomyComplex aortoiliac aneurysmsIntra-abdominal aneurysmsFemoral-femoral bypassRinged PTFE graftEndovascular aneurysm repairKidney transplant functionFunctioning kidney transplantExternal iliac arteryRisk of ruptureSciatica symptomsAortoiliac aneurysmsVariations in Antithrombotic Combinations and Prescription Durations After Lower Extremity Revascularization in Patients With Peripheral Arterial Disease
Wells N, Alameddine D, Dhanda U, Tran L, Silva D, Slade M, Guzman R, Chaar C. Variations in Antithrombotic Combinations and Prescription Durations After Lower Extremity Revascularization in Patients With Peripheral Arterial Disease. Journal Of Vascular Surgery 2024, 80: e135-e136. DOI: 10.1016/j.jvs.2024.07.076.Peer-Reviewed Original ResearchOutcomes of Mechanical Thrombectomy for Acute Limb Ischemia at a Tertiary Referral Center
Loh S, Strosberg D, Chaar C, Guzman R, Tonnessen B. Outcomes of Mechanical Thrombectomy for Acute Limb Ischemia at a Tertiary Referral Center. Journal Of Vascular Surgery 2024, 80: e121-e122. DOI: 10.1016/j.jvs.2024.07.058.Peer-Reviewed Original ResearchThe Incidence and Impact of Cardiac Function Decline after Lower Extremity Revascularization
Jamil Y, Huttler J, Alameddine D, Wu Z, Mena-Hurtado C, Velazquez E, Guzman R, Ochoa Chaar C. The Incidence and Impact of Cardiac Function Decline after Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 110: 414-423. PMID: 39343374, DOI: 10.1016/j.avsg.2024.07.119.Peer-Reviewed Original ResearchCardiac functional declineStable cardiac functionLower extremity revascularizationPeripheral arterial diseaseCardiac functionFollow-upExtremity revascularizationFunctional declineElectronic records of patientsKaplan-Meier analysisRecords of patientsMode of revascularizationAdverse limb eventsLower-extremity revascularizationTransthoracic echocardiogramReintervention rateHeart failureDiabetes mellitusPeriprocedural bleedingPatient characteristicsArtery diseasePatientsLimb eventsIncreased mortalityRevascularizationThe radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access
Brahmandam A, Huttler J, Bellamkonda K, Setia O, Cardella J, Stewart W, Guzman R, Ochoa Chaar C. The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access. Journal Of Vascular Surgery 2024, 80: a21-a22. DOI: 10.1016/j.jvs.2024.07.019.Peer-Reviewed Original ResearchThe Degree of Inferior Vena Cava Filter Tilt Associated with Challenging Retrieval
Kostiuk V, Grubman S, Brahmandam A, Schneider E, Tonnessen B, Perez Lozada J, Guzman R, Ochoa Chaar C. The Degree of Inferior Vena Cava Filter Tilt Associated with Challenging Retrieval. Annals Of Vascular Surgery 2024, 109: 135-142. PMID: 39025218, DOI: 10.1016/j.avsg.2024.06.020.Peer-Reviewed Original ResearchIVC filter tiltInferior vena cavaInferior vena cava filter retrievalFilter tiltEndovascular techniquesFilter retrievalInferior vena cava axisRight jugular vein accessInferior vena cava diameterElectronic charts of patientsInferior vena cava filter removalAssociated with technical difficultiesCharts of patientsFailed retrievalJugular vein accessLowest renal veinRight jugular veinRegression analysisFilter placementIVC filtersRenal veinVein accessVena cavaProcedural characteristicsFilter removalPresentation and patterns of reinterventions after revascularization in patients with premature peripheral arterial disease
Sivakumar A, Satam K, Wu Z, Alameddine D, Aboian E, Chaer R, Schermerhorn M, Moreira C, Guzman R, Ochoa Chaar C. Presentation and patterns of reinterventions after revascularization in patients with premature peripheral arterial disease. Journal Of Vascular Surgery 2024, 80: 1776-1785.e1. PMID: 39002606, DOI: 10.1016/j.jvs.2024.07.021.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseLower extremity revascularizationOlder patientsPeripheral arterial diseaseArtery diseaseRetrospective review of consecutive patientsReview of consecutive patientsDistressed Communities IndexAge of presentationFrequency of reinterventionsEnd-stage renal diseaseKaplan-Meier curvesOutcomes of lower extremity revascularizationLong-term outcomesCoronary artery diseaseMALE-free survivalAdverse limb eventsOverall survivalReintervention rateConsecutive patientsFrequent reinterventionsPerioperative complicationsRetrospective reviewNo significant differenceInstitutional experienceArtificial Intelligence Improves Initial Evaluation and Follow-up of Patients With AAAs
Kostiuk V, Rodriguez P, Loh S, Wilson E, Yao K, Bader J, Mojibian H, Fischer U, Guzman R, Kuwayama D, Chaar C, Aboian E. Artificial Intelligence Improves Initial Evaluation and Follow-up of Patients With AAAs. Journal Of Vascular Surgery 2024, 79: e131-e132. DOI: 10.1016/j.jvs.2024.03.163.Peer-Reviewed Original ResearchOpen and Endovascular Treatment of the Common Femoral Artery in a Tertiary Care Center
Wells N, Hundito A, Tuttle M, Alameddine D, Aboian E, Arhuidese I, Fischer U, Perez-Lozada J, Guzman R, Chaar C. Open and Endovascular Treatment of the Common Femoral Artery in a Tertiary Care Center. Journal Of Vascular Surgery 2024, 79: e45-e46. DOI: 10.1016/j.jvs.2024.03.032.Peer-Reviewed Original ResearchEndoscopic Transaxillary First Rib Resection
Setia O, Strosberg D, Blasberg J, Schwartz J, Tonnessen B, Cardella J, Zwibelman H, Guzman R. Endoscopic Transaxillary First Rib Resection. Journal Of Vascular Surgery 2024, 79: e115. DOI: 10.1016/j.jvs.2024.03.139.Peer-Reviewed Original ResearchThe radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access
Brahmandam A, Huttler J, Bellamkonda K, Setia O, Cardella J, Stewart W, Guzman R, Ochoa Chaar C. The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access. Journal Of Vascular Surgery 2024, 79: a17-a18. DOI: 10.1016/j.jvs.2024.04.032.Peer-Reviewed Original ResearchComparative Outcomes of Peripheral Vascular Intervention in Patients Discharged on Clopidogrel in Combination With Factor Xa Inhibitors or Aspirin
Huttler J, Rodriguez P, Dandu C, Piazza G, Kabbani L, Kashyap V, Slade M, Zwibelman H, Guzman R, Chaar C. Comparative Outcomes of Peripheral Vascular Intervention in Patients Discharged on Clopidogrel in Combination With Factor Xa Inhibitors or Aspirin. Journal Of Vascular Surgery 2024, 79: e290-e292. DOI: 10.1016/j.jvs.2024.03.375.Peer-Reviewed Original ResearchThe Incidence and Significance of Bleeding in Patients With Advanced Peripheral Arterial Disease
Hundito A, Wells N, Tuttle M, Alameddine D, Huttler J, Slade M, Strosberg D, Lee A, Guzman R, Chaar C. The Incidence and Significance of Bleeding in Patients With Advanced Peripheral Arterial Disease. Journal Of Vascular Surgery 2024, 79: e60-e61. DOI: 10.1016/j.jvs.2024.03.051.Peer-Reviewed Original ResearchClinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization
Pinto Rodriguez P, Alameddine D, Huttler J, Damara F, Slade M, Cardella J, Guzman R, Chaar C. Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 106: 350-359. PMID: 38810726, DOI: 10.1016/j.avsg.2024.02.031.Peer-Reviewed Original ResearchPeripheral vascular interventionsPeripheral arterial diseaseLower body mass indexUnderweight patientsLong-term outcomesBody mass indexNonobese patientsMass indexRetrospective analysis of patientsRate of thrombotic complicationsHigher 30-day mortalityRates of amputation-free survivalRate of reinterventionOutcomes of patientsPeripheral arterial disease patientsAnalysis of patientsKaplan-Meier analysisImpact of malnutritionBaseline demographic characteristicsChronic limb-threatening ischemiaEpidemic of obesityOptimization of nutritionLonger hospital lengthAdverse limb eventsAmputation-free survivalIntravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions
Brahmandam A, Kim T, Parziale S, Deng Y, Setia O, Tonnessen B, Ochoa Chaar C, Guzman R, Aboian E. Intravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions. Annals Of Vascular Surgery 2024, 106: 410-418. PMID: 38810722, DOI: 10.1016/j.avsg.2024.03.008.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaChronic limb threatening ischemia patientsGeneralized estimating equationsPeripheral vascular interventionsPeripheral arterial diseaseAssociated with improved patencyPredictors of 1-year outcomeIntravascular ultrasound useVascular Quality InitiativeSubgroup analysisAdjunctive useD lesionsTASC CPropensity matchingTreatment modalitiesTrans-Atlantic Inter-Society Consensus (TASC) classificationMajor amputationLimb-threatening ischemiaBalloon angioplastyIntravascular ultrasoundImproved patencyUltrasound useOne-year followQuality InitiativePredictors of patencyAbstract 146: Phosphodiesterase 10A Mediates Arterial Calcification Through A P38/MAPK-MMP3 Signaling
Jin Y, Xie Y, Berezowitz A, Davis S, Flores A, Wang X, Guzman R, Cai Y. Abstract 146: Phosphodiesterase 10A Mediates Arterial Calcification Through A P38/MAPK-MMP3 Signaling. Arteriosclerosis Thrombosis And Vascular Biology 2024, 44: a146-a146. DOI: 10.1161/atvb.44.suppl_1.146.Peer-Reviewed Original ResearchVascular smooth muscle cellsChronic kidney diseasePeripheral arterial diseaseArtery calcificationInhibition of PDE10AMedial arterial calcificationVascular calcificationAssociated with increased cardiovascular morbidityCalcifying vascular smooth muscle cellsMatrix metallopeptidaseSmooth muscle cellsVSMCs in vitroCyclic nucleotides cAMPArteries in vivoMMP-3 upregulationCardiovascular morbidityCalcification in vivoArtery diseaseVon Kossa stainingKidney diseaseMuscle cellsRodent modelsVSMC calcificationInducible isoformCalcium assayFasting Duration Prior to Venography Is Associated with Stent Size in Patients with Iliac Vein Compression
Schultz K, Rodriguez P, Hamdi S, Attaran R, Lozada J, Huber S, Tonnessen B, Aboian E, Guzman R, Chaar C. Fasting Duration Prior to Venography Is Associated with Stent Size in Patients with Iliac Vein Compression. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2024, 12: 101774. DOI: 10.1016/j.jvsv.2024.101774.Peer-Reviewed Original Research