2010
Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2
Petrucelli N, Daly M, Feldman G. Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2. Genetics In Medicine 2010, 12: 245-259. PMID: 20216074, DOI: 10.1097/gim.0b013e3181d38f2f.Peer-Reviewed Original ResearchConceptsBRCA1/2 mutationsBRCA2 mutationsHereditary breastTesting of at-risk relativesFamily history of cancerOvarian cancerAt-risk relativesPrimary prevention optionsHistory of cancerPrevalence of BRCA1/2 mutationsEstimates of penetranceAshkenazi Jewish populationCancer riskProphylactic surgeryPrevention optionsFamily historyBRCA2 genesEarly interventionFamily membersBRCA2Increased surveillanceFamilial mutationsBRCA1/2BRCA1Jewish population
2004
Quality of Life After Prophylactic Oophorectomy
Daly M. Quality of Life After Prophylactic Oophorectomy. 2004 DOI: 10.21236/ada428590.Peer-Reviewed Original ResearchQuality of lifeCancer risk reduction strategiesIncreased risk of ovarian cancerRisk of ovarian cancerRisk-reducing surgeryCompletion of data collectionOvarian cancerQuality of life implicationsRisk reduction strategiesSexual activity frequencyProphylactic oophorectomyProphylactic surgeryCoping strategiesStudy womenStudy outcomesSocial functioningIncreased riskSurgery groupData collectionNight sweatsShort-term differencesLife implicationsHot flashesClinical managementWomen