Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women with a BRCA1 or BRCA2 Mutation
Finch A, Beiner M, Lubinski J, Lynch H, Moller P, Rosen B, Murphy J, Ghadirian P, Friedman E, Foulkes W, Kim-Sing C, Wagner T, Tung N, Couch F, Stoppa-Lyonnet D, Ainsworth P, Daly M, Pasini B, Gershoni-Baruch R, Eng C, Olopade O, McLennan J, Karlan B, Weitzel J, Sun P, Narod S. Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women with a BRCA1 or BRCA2 Mutation. Obstetrical & Gynecological Survey 2007, 62: 29-31. DOI: 10.1097/01.ogx.0000251480.69322.50.Peer-Reviewed Original ResearchRisk of ovarian cancerBRCA2 mutationsBRCA1 mutationsPeritoneal cancerOvarian cancerSalpingo-oophorectomyFallopian tubeIntact ovariesIncreased lifetime risk of ovarian cancerEstimated risk of ovarian cancerFollow-upLifetime risk of ovarian cancerBilateral salpingo-oophorectomyPrimary peritoneal cancerBRCA mutation carriersMultivariable hazard ratiosIncreased lifetime riskYears of ageBilateral oophorectomyProphylactic oophorectomyBRCA2 genesIncident cancerOophorectomyCumulative incidenceProspective study