1999
Endothelial Cell Growth Factor Enhances Musculocutaneous Flap Survival Through the Process of Neovascularization
Pu L, Ahmed S, Thomson J, Reid M, Madsen J, Restifo R. Endothelial Cell Growth Factor Enhances Musculocutaneous Flap Survival Through the Process of Neovascularization. Annals Of Plastic Surgery 1999, 42: 306-312. PMID: 10096623, DOI: 10.1097/00000637-199903000-00013.Peer-Reviewed Original ResearchConceptsLocal intra-arterial injectionIntra-arterial injectionProcess of neovascularizationCell growth factorFlap survivalLocal injectionGroup BRat transverse rectus abdominis musculocutaneous (TRAM) flap modelControl groupGrowth factorInferior vascular pedicleIntra-arterial routePostoperative day 7Endothelial cell growth factorMusculocutaneous flap modelSignificant increaseTRAM flapFlap elevationGroup ASurvival areaVascular pedicleGroup CDay 7Flap model
1998
The Preconditioned TRAM Flap: Preliminary Clinical Experience
Restifo R, Thomson J. The Preconditioned TRAM Flap: Preliminary Clinical Experience. Annals Of Plastic Surgery 1998, 41: 343-347. PMID: 9788213, DOI: 10.1097/00000637-199810000-00001.Peer-Reviewed Original ResearchConceptsTRAM flapFat necrosisIschemic preconditioningMusculocutaneous flapPartial flap failure rateTransverse rectus abdominis musculocutaneous flapAcute ischemic preconditioningHigh-risk patientsLow-risk patientsRectus abdominis musculocutaneous flapFlap failure rateHigh-risk groupPartial flap lossPreliminary clinical experienceObese patientsFree TRAMClinical efficacyFlap lossClinical experiencePatientsClinical situationsPreliminary experienceFlapUnderserved areasNecrosisComparison of the Effects of Ischemic Preconditioning and Surgical Delay on Pedicled Musculocutaneous Flap Survival in a Rat Model
Zahir K, Syed S, Zink J, Restifo R, Thomson J. Comparison of the Effects of Ischemic Preconditioning and Surgical Delay on Pedicled Musculocutaneous Flap Survival in a Rat Model. Annals Of Plastic Surgery 1998, 40: 422-429. PMID: 9555999, DOI: 10.1097/00000637-199804000-00017.Peer-Reviewed Original ResearchConceptsEffects of IPCSurgical delayIschemic preconditioningMusculocutaneous flapFlap survivalRat modelMale Sprague-Dawley ratsTransverse rectus abdominis musculocutaneous flapFifth postoperative dayRectus abdominis musculocutaneous flapSprague-Dawley ratsSame operative sessionMusculocutaneous flap modelPedicled musculocutaneous flapT-testStudent's t-testPostoperative daySimilar efficacyTRAM flapIP groupSurgical proceduresFlap elevationOperative sessionFlap viabilityFlap model