Featured Publications
The role of adipose tissue in cardiovascular health and disease
Oikonomou EK, Antoniades C. The role of adipose tissue in cardiovascular health and disease. Nature Reviews Cardiology 2018, 16: 83-99. PMID: 30287946, DOI: 10.1038/s41569-018-0097-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdipose tissueCardiovascular systemCardiovascular healthInsulin resistance leadPro-atherogenic profileCardiovascular risk stratificationAdipose tissue functionAdipose tissue biologyComplex homeostatic mechanismsRisk stratificationLocal inflammationCardiovascular diseasePossible clinical translationParacrine effectsTherapeutic targetingHomeostatic mechanismsDiseaseGaseous messengerTissueClinical translationTissue biologyTissue functionCrucial regulatorCurrent knowledgeHealth
2020
Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease
Oikonomou EK, Siddique M, Antoniades C. Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease. Cardiovascular Research 2020, 116: 2040-2054. PMID: 32090243, PMCID: PMC7585409, DOI: 10.1093/cvr/cvaa021.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiac computed tomographyNon-invasive imagingCardiovascular imagingCardiovascular diseaseNon-invasive cardiovascular imagingCardiac CTCardiovascular risk stratificationFirst-line optionImportant clinical implicationsRisk stratificationUnstable patientsClinical careComputed tomographyCurrent evidenceClinical implicationsCardiac imagingRadiomics approachPatientsRadiomics methodTissue biologyCardiovascular diagnosticsDiseaseFuture studiesImagingPhenotyping
2018
Development and Validation of a Clinical Score for Cardiovascular Risk Stratification of Long‐Term Childhood Cancer Survivors
Oikonomou EK, Athanasopoulou SG, Kampaktsis PN, Kokkinidis DG, Papanastasiou CA, Feher A, Steingart RM, Oeffinger KC, Gupta D. Development and Validation of a Clinical Score for Cardiovascular Risk Stratification of Long‐Term Childhood Cancer Survivors. The Oncologist 2018, 23: 965-973. PMID: 29593100, PMCID: PMC6156177, DOI: 10.1634/theoncologist.2017-0502.Peer-Reviewed Original ResearchConceptsLong-term childhood cancer survivorsChildhood cancer survivorsCardiovascular risk stratificationCardiovascular mortalityCancer survivorsRisk scoreCardiovascular riskRisk stratificationRisk of CVMTreatment-related adverse eventsAdverse cardiovascular eventsRisk stratification toolSimple risk scoreCongestive heart failureCumulative incidence rateEnd Results ProgramMedian time periodPopulation-based studyHistory of lymphomaHigh-risk groupLow-risk groupSimple clinical toolHistory of radiationNon-white raceHealth care providers