2024
mRNA Vaccines Against Tick‐borne Diseases
Arora G, Fikrig E. mRNA Vaccines Against Tick‐borne Diseases. 2024, 285-301. DOI: 10.1002/9783527838394.ch10.Peer-Reviewed Original ResearchTick-borne diseasesMRNA vaccinesIxodes scapularis ticksCrimean-Congo hemorrhagic feverEffective memory responsesVector-borne diseasesIncreasing cost of developmentPowassan virusModified mRNA vaccineMRNA-based vaccinesTicksVaccine platformTurnover timeLipid nanoparticlesMemory responsesClinical trialsImmune systemEffective vaccineMultiple antigensPathogensSpreading virusArthropodsVaccineDiseaseHemorrhagic fever
2019
Polymicrobial Nature of Tick-Borne Diseases
Sanchez-Vicente S, Tagliafierro T, Coleman J, Benach J, Tokarz R, Azad A, Fikrig E, Munderloh U, Telford S. Polymicrobial Nature of Tick-Borne Diseases. MBio 2019, 10: e02055-19. PMID: 31506314, PMCID: PMC6737246, DOI: 10.1128/mbio.02055-19.Peer-Reviewed Original ResearchConceptsPolymicrobial infectionsClinical spectrumTick-borne diseasesFatal infectionPowassan virusDisproportionate incidenceTick-borne diseaseDifficult diagnosisNew pathogensNew agentsPolymicrobial natureDisease severityInfectionDiseaseLyme diseasePrevalent pathogenBorreliaHigh rateIncidenceDiagnosisSeverityRickettsiaTick vectorVirusClimate change