Domenica Berardi
Postdoctoral AssociateAbout
Research
Publications
2026
Demographic, birth, parental characteristics, and the risk of early‐onset colorectal cancer: A population‐based nested case‐control study in California
Siddique S, Wang R, Berardi D, Johnson C, Wiemels J, Metayer C, Ma X. Demographic, birth, parental characteristics, and the risk of early‐onset colorectal cancer: A population‐based nested case‐control study in California. Cancer 2026, 132: e70458. PMID: 42324895, PMCID: PMC13284631, DOI: 10.1002/cncr.70458.Peer-Reviewed Original ResearchThis study investigates early-onset colorectal cancer, showing male sex, Hispanic ethnicity, high birthweight, and older paternal age increase risk, while foreign-born mothers may reduce it.Evaluating 1,4-Dioxane Exposure in Long Island, New York: Integrating Environmental, Biological, and Metabolomic Measures
Deziel N, Liu S, Johnson N, Berardi D, Clark C, Loughlin C, Sorrentino K, Lin E, Ning X, Warren J, Liew Z, Johnson C, Pollitt K. Evaluating 1,4-Dioxane Exposure in Long Island, New York: Integrating Environmental, Biological, and Metabolomic Measures. Environmental Science And Technology 2026, 60: 9048-9060. PMID: 41824932, PMCID: PMC13045016, DOI: 10.1021/acs.est.5c15309.Peer-Reviewed Original Research
2025
Discovery of a Widespread Polyamine–Low-Molecular-Weight Thiol Hybrid Pathway in Clostridioides difficile
Hunt R, Oh J, Jain A, Kuo T, Berardi D, Jian W, Song D, Wu Q, Goodman A, Palm N, Zimmermann M, Johnson C, Crawford J. Discovery of a Widespread Polyamine–Low-Molecular-Weight Thiol Hybrid Pathway in Clostridioides difficile. ACS Infectious Diseases 2025, 11: 2246-2264. PMID: 40671632, PMCID: PMC12403189, DOI: 10.1021/acsinfecdis.5c00286.Peer-Reviewed Original ResearchSenescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype
Berardi D, Farrell G, AlSultan A, McCulloch A, Hall N, Sousa R, Jimenez M, Selman C, Bellantuono I, Johnson C, Rattray Z, Rattray N. Senescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype. Aging Cell 2025, 24: e70127. PMID: 40530891, PMCID: PMC12341781, DOI: 10.1111/acel.70127.Peer-Reviewed Original ResearchSex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase
Aladelokun O, Benitez K, Wang Y, Jain A, Berardi D, Maroun G, Shen X, Roper J, Gibson J, Sumigray K, Khan S, Johnson C. Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase. Pharmacological Research 2025, 215: 107736. PMID: 40228761, PMCID: PMC12100670, DOI: 10.1016/j.phrs.2025.107736.Peer-Reviewed Original Research
2024
Charting the metabolic biogeography of the colorectum in cancer: challenging the right sided versus left sided classification
Jain A, Morris M, Berardi D, Arora T, Domingo-Almenara X, Paty P, Rattray N, Kerekes D, Lu L, Khan S, Johnson C. Charting the metabolic biogeography of the colorectum in cancer: challenging the right sided versus left sided classification. Molecular Cancer 2024, 23: 211. PMID: 39342363, PMCID: PMC11438248, DOI: 10.1186/s12943-024-02133-5.Peer-Reviewed Original ResearchRecounting the untold stories of breast cancer patient experiences: lessons learned from a patient–public involvement and engagement storytelling event
Cunningham M, Rattray N, McFadden Y, Berardi D, Daramy K, Kelly P, Galbraith A, Lochiel I, Mills L, Scott Y, Chalmers S, Lannigan A, Rattray Z. Recounting the untold stories of breast cancer patient experiences: lessons learned from a patient–public involvement and engagement storytelling event. International Journal Of Pharmacy Practice 2024, 32: 515-523. PMID: 39305489, DOI: 10.1093/ijpp/riae052.Peer-Reviewed Original ResearchAsparagine synthetase and G‐protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer
Lu L, Zhang Q, Aladelokun O, Berardi D, Shen X, Marin A, Garcia‐Milian R, Roper J, Khan S, Johnson C. Asparagine synthetase and G‐protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer. International Journal Of Cancer 2024, 156: 52-68. PMID: 39039782, PMCID: PMC11537827, DOI: 10.1002/ijc.35104.Peer-Reviewed Original Research
2023
Perfluorooctanesulfonic Acid and Perfluorooctanoic Acid Promote Migration of Three-Dimensional Colorectal Cancer Spheroids
Zheng J, Sun B, Berardi D, Lu L, Yan H, Zheng S, Aladelokun O, Xie Y, Cai Y, Pollitt K, Khan S, Johnson C. Perfluorooctanesulfonic Acid and Perfluorooctanoic Acid Promote Migration of Three-Dimensional Colorectal Cancer Spheroids. Environmental Science And Technology 2023, 57: 21016-21028. PMID: 38064429, PMCID: PMC12903201, DOI: 10.1021/acs.est.3c04844.Peer-Reviewed Original Research
2022
Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
Altea-Manzano P, Vandekeere A, Edwards-Hicks J, Roldan M, Abraham E, Lleshi X, Guerrieri A, Berardi D, Wills J, Junior J, Pantazi A, Acosta J, Sanchez-Martin R, Fendt S, Martin-Hernandez M, Finch A. Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells. Molecular Cell 2022, 82: 4537-4547.e7. PMID: 36327975, DOI: 10.1016/j.molcel.2022.10.005.Peer-Reviewed Original Research