1996
Autologous granulosa cell coculture demonstrates zygote suppression of granulosa cell steroidogenesis**Presented in part at the 51st Annual Meeting of the American Society for Reproductive Medicine. Seattle, Washington, October 7 to 12, 1995.††Supported in part by Physician Scientist Award (AG00566 [D.B.S.] and R01HD31894 [A.L.S.]) from the National Institutes of Health, National Institute on Aging, Bethesda, Maryland.
Seifer D, Freeman M, Gardiner A, Hill G, Schneyer A, Vanderhyden B. Autologous granulosa cell coculture demonstrates zygote suppression of granulosa cell steroidogenesis**Presented in part at the 51st Annual Meeting of the American Society for Reproductive Medicine. Seattle, Washington, October 7 to 12, 1995.††Supported in part by Physician Scientist Award (AG00566 [D.B.S.] and R01HD31894 [A.L.S.]) from the National Institutes of Health, National Institute on Aging, Bethesda, Maryland. Fertility And Sterility 1996, 66: 425-429. PMID: 8751742, DOI: 10.1016/s0015-0282(16)58513-6.Peer-Reviewed Original ResearchConceptsLuteinized granulosa cellsGranulosa cellsStandard IVF-ET treatment cycleIVF-ET treatment cyclesTwo-pronuclear embryosGranulosa cell steroidogenesisTwo-pronuclear zygotesNational InstituteVitro Fertilization UnitProduction of E2Steroid hormone productionPituitary desensitizationOvarian stimulationFollicular aspiratesCell steroidogenesisFertilization unitTreatment cyclesHormone productionCell coculturesReproductive medicineP productionAmerican SocietyAcademic research environmentE2Human embryos
1991
Early pituitary desensitization and ovarian suppression with leuprolide acetate is associated with in vitro fertilization-embryo transfer success**Presented in part at the Society for Gynecologic Investigation, San Antonio, Texas, March 20 to 23, 1991.
Seifer D, Thornton K, DeCherney A, Lavy G. Early pituitary desensitization and ovarian suppression with leuprolide acetate is associated with in vitro fertilization-embryo transfer success**Presented in part at the Society for Gynecologic Investigation, San Antonio, Texas, March 20 to 23, 1991. Fertility And Sterility 1991, 56: 500-504. PMID: 1909977, DOI: 10.1016/s0015-0282(16)54548-8.Peer-Reviewed Original ResearchConceptsLeuprolide acetatePituitary desensitizationOvarian suppressionPregnancy ratePg/Group IOvarian hyperstimulationIVF-ETE2 responseGroup IIHuman menopausal gonadotropinControlled ovarian hyperstimulationFertilization-embryo transferSerum estradiol levelsNumber of oocytesHuman chorionic gonadotropinHigher pregnancy ratePg/mLMenopausal gonadotropinIVF patientsRetrospective seriesEstradiol levelsGynecologic InvestigationInfertility practiceMenstrual cycle