Damianos Kokkinidis, MD
Staff Affiliate - YNHHCards
About
Research
Publications
2026
Assessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention
Kyriakoulis I, Csecs I, Ahmed A, Wright C, Shanbhag A, Lemley M, Slomka P, Sinusas A, Miller E, Kokkinidis D, Feher A. Assessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention. JACC Advances 2026, 5: 102732. PMID: 42000549, PMCID: PMC13098618, DOI: 10.1016/j.jacadv.2026.102732.Peer-Reviewed Original Researchmajor adverse cardiac eventscoronary artery calciumatherosclerotic cardiovascular diseasenuclear myocardial perfusion imagingmyocardial perfusion imagingmyocardial infarctionperfusion imagingrisk of Major Adverse Cardiac Eventssecondary preventioncoronary artery calcium scoresevere coronary artery calciumMedian Follow-Upprimary prevention groupadverse cardiac eventsmultivariate Cox regressioncomposite of deathatherosclerotic cardiovascular disease patientsequivalent riskperipheral arterial diseaselate revascularizationaggressive managementartery calciumattenuation-correctedcardiac eventssevere calcificationCoronary calcifications and myocardial flow reserve in heart transplant patients: a longitudinal study
Wright C, Kiage J, Kyriakoulis I, Csecs I, Ahmed A, Tong G, Zeng Y, Liu Y, Bellumkonda L, Kokkinidis D, Sinusas A, Miller E, Feher A. Coronary calcifications and myocardial flow reserve in heart transplant patients: a longitudinal study. European Heart Journal 2026, 47: 3214-3216. PMID: 41780909, DOI: 10.1093/eurheartj/ehag163.Peer-Reviewed Original ResearchNoninvasive Imaging Modalities for the Evaluation of Coronary Artery Disease Among Patients With High Body Mass Index: A Focus on Coronary Computed Tomography Angiography (CCTA)
Kyriakoulis I, Sunil Kumar S, Palaiodimos L, Kokkinidis D. Noninvasive Imaging Modalities for the Evaluation of Coronary Artery Disease Among Patients With High Body Mass Index: A Focus on Coronary Computed Tomography Angiography (CCTA). The American Journal Of Cardiology 2026, 266: 70-76. PMID: 41722634, DOI: 10.1016/j.amjcard.2026.02.023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCoronary Computed Tomography Angiographybody mass indexcoronary artery diseaseHigher Body Mass Indexartery diseasemass indexobstructive coronary artery diseaseevaluation of coronary artery diseasecomputed tomography angiographytreadmill stress testnoninvasive imaging modalitycardiovascular risk factorshigh radiation dosesattenuation artifactsrisk factorsradiation dosenuclear imagingpatientscardiovascular diseaseimaging modalitiesnoninvasive methodobesityadult populationangiographydisease
2025
A comparative analysis of cadmium-zinc-telluride single-photon emission computed tomography/computed tomography to conventional single-photon emission computed tomography and positron emission tomography: Implications for risk stratification
Ahmed A, Csecs I, Wright C, Kyriakoulis I, Kokkinidis D, Miller E, Feher A. A comparative analysis of cadmium-zinc-telluride single-photon emission computed tomography/computed tomography to conventional single-photon emission computed tomography and positron emission tomography: Implications for risk stratification. Journal Of Nuclear Cardiology 2025, 58: 102583. PMID: 41325821, DOI: 10.1016/j.nuclcard.2025.102583.Peer-Reviewed Original ResearchThe Additive Value of FFR-CT in the Evaluation of Calcified Coronary Arteries With Coronary CT Angiography
Kyriakoulis I, Nanna M, Rao-Brito M, Cambi B, Mazzarelli L, Kokkinidis D. The Additive Value of FFR-CT in the Evaluation of Calcified Coronary Arteries With Coronary CT Angiography. The American Journal Of Cardiology 2025, 259: 74-80. PMID: 41015170, DOI: 10.1016/j.amjcard.2025.09.024.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCoronary Computed Tomography Angiographysevere coronary artery calcificationcoronary artery calcificationcoronary CT angiographyFFR-CTdiagnostic performanceCT angiographydiagnosis of obstructive coronary artery diseaseaccuracy of coronary computed tomography angiographyevaluation of chest painobstructive coronary artery diseasecoronary arterynegative predictive valuecoronary artery diseasefractional flow reserveadditive valuecalcified coronary arterieschest painfalse positive findingsinvasive FFRartery calcificationartery diseaseflow reserveangiographypredictive valueCCTA and CACS for preoperative cardiovascular risk stratification in patients undergoing noncardiac surgery: A systematic review and meta-analysis
Kyriakoulis I, Kyriakoulis K, Aznaouridis K, Sunil Kumar S, Schizas D, Kokkinidis D. CCTA and CACS for preoperative cardiovascular risk stratification in patients undergoing noncardiac surgery: A systematic review and meta-analysis. Journal Of Cardiovascular Computed Tomography 2025, 19: 648-655. PMID: 40681455, DOI: 10.1016/j.jcct.2025.06.007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statementscoronary artery calcium scoreCoronary Computed Tomography Angiographymajor adverse cardiovascular eventspooled positive predictive valuesevere CACSnegative predictive valuepostoperative major adverse cardiovascular eventsnoncardiac surgerycardiovascular risk stratificationobstructive stenosisrisk stratificationcoronary artery calcium scoring resultspreoperative coronary computed tomography angiographyspecificity of coronary computed tomography angiographylong-term major adverse cardiovascular eventsmeta-analyses of proportionslong-term postoperative periodpredictive valueartery calcium scorenoninvasive cardiac imagingmeta-analysislong-term morbiditycomputed tomography angiographymyocardial perfusion imagingpositive predictive valueCoronary Computed Angiography and Coronary Artery Calcium Score for Preoperative Cardiovascular Risk Stratification in Patients Undergoing Noncardiac Surgery
Kyriakoulis I, Kumar S, Lianos G, Schizas D, Kokkinidis D. Coronary Computed Angiography and Coronary Artery Calcium Score for Preoperative Cardiovascular Risk Stratification in Patients Undergoing Noncardiac Surgery. Journal Of Cardiovascular Development And Disease 2025, 12: 159. PMID: 40278217, PMCID: PMC12027494, DOI: 10.3390/jcdd12040159.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statementscoronary artery calcium scoremajor adverse cardiovascular eventspostoperative major adverse cardiovascular eventsartery calcium scorenoncardiac surgerycalcium scorerisk stratificationcomputed angiographyseverity of coronary artery diseasepreoperative imaging protocolrisk evaluation of patientspreoperative risk stratificationhigh-risk patientsevaluation of patientsinfluence surgical decisionsadverse cardiovascular eventscoronary artery diseasecardiovascular risk stratificationperioperative risk predictionsuperior prognostic performancestratify patientsanatomical assessmentsurgical decisioncardiovascular eventsprognostic performanceEpidemiological Profile and Mortality of Infective Endocarditis Over the Past Decade: A Systematic Review and Meta-Analysis of 133 Studies
Tzoumas A, Sagris M, Xenos D, Ntoumaziou A, Kyriakoulis I, Kakargias F, Liaqat W, Nagraj S, Patel R, Korosoglou G, Tousoulis D, Tsioufis K, Kokkinidis D, Palaiodimos L. Epidemiological Profile and Mortality of Infective Endocarditis Over the Past Decade: A Systematic Review and Meta-Analysis of 133 Studies. The American Journal Of Cardiology 2025, 244: 67-88. PMID: 40015544, DOI: 10.1016/j.amjcard.2025.02.023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statementsinfective endocarditiscausative microorganismsmortality of infective endocarditisepidemiological profiletricuspid valve IEviridans group streptococcimortality raterandom-effects model meta-analysismeta-analysisprofile of IEshort-term mortality rateincidence of health-caresystematic reviewincreasingly prevalent conditiongroup streptococciaffected valvePubMed/MEDLINE databasemitral valveStaphylococcus speciesaortic valvecardiac valvesincreased incidenceStreptococci speciesenterococci speciesS. aureusSignificance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging
Kokkinidis D, Kyriakoulis I, Chui P, Agarwal R, Liu Y, Khera R, Sinusas A, Velazquez E, Miller E, Feher A. Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging. JACC Advances 2025, 4: 101618. PMID: 39983619, PMCID: PMC11891677, DOI: 10.1016/j.jacadv.2025.101618.Peer-Reviewed Original Researchcoronary artery calcificationmyocardial perfusion imagingischemic ECG changeslow event ratesECG changesnormal perfusionartery calcificationperfusion imagingsingle-photon emission computed tomography/computed tomographystress ECGCAC evaluationpresence of coronary artery calcificationsuspected coronary artery diseaseMedian Follow-Upevent ratesischemic electrocardiographic changesanalysis to patientscomposite endpoint ratecoronary artery diseaseTomography/Computed Tomographyprognostic informationMACE rateFollow-upsubgroup analysisadverse outcomesMultivalvular vs single-valve infective endocarditis: a systematic review and meta-analysis
Kyriakoulis I, Tzoumas A, Kyriakoulis K, Kardoutsos I, Ntoumaziou A, Nagraj S, Kokkinidis D, Palaiodimos L. Multivalvular vs single-valve infective endocarditis: a systematic review and meta-analysis. Future Cardiology 2025, 21: 113-121. PMID: 39882735, PMCID: PMC11812418, DOI: 10.1080/14796678.2025.2457898.Peer-Reviewed Original ResearchConceptssystemic embolic eventsinfective endocarditisembolic eventsheart failureassociated with increased risk of short-term mortalityrisk of short-term mortalityassociated with increased risklikelihood of poor prognosisrisk of complicationsone-year mortalitystudy of patientsshort-term mortalityheart valvesclinical suspicionsurgical managementpoor prognosisendocarditisvirulent microorganismspatientsinclusion criteriaIdentified studiesmortalityprognosissystematic searchheart