2011
Gap junction‐mediated calcium waves define communication networks among murine postnatal neural progenitor cells
Lacar B, Young SZ, Platel J, Bordey A. Gap junction‐mediated calcium waves define communication networks among murine postnatal neural progenitor cells. European Journal Of Neuroscience 2011, 34: 1895-1905. PMID: 22098557, PMCID: PMC3237798, DOI: 10.1111/j.1460-9568.2011.07901.x.Peer-Reviewed Original ResearchConceptsNeural progenitor cellsNeurogenic nicheB2 cellsBlood vesselsCalcium wavesPurinergic receptor blockerProgenitor cellsPostnatal neurogenic nichesFunctional couplingPostnatal neural progenitor cellsGap junction blockersGap junction protein connexin 43Neonatal electroporationNiche astrocytesReceptor blockersProtein connexin 43Intercellular calcium wavesSubventricular zoneCells persistJunction blockersB1 cellsB cellsDye couplingDistinct entityConnexin 43
2009
Ependymal cells along the lateral ventricle express functional P2X7 receptors
Genzen JR, Platel JC, Rubio ME, Bordey A. Ependymal cells along the lateral ventricle express functional P2X7 receptors. Purinergic Signalling 2009, 5: 299-307. PMID: 19274488, PMCID: PMC2717311, DOI: 10.1007/s11302-009-9143-5.Peer-Reviewed Original ResearchP2X7 receptorEpendymal cellsSubventricular zoneWhole-cell patch-clamp recordingsCentral nervous system injuryFunctional P2X7 receptorsFunctional purinergic receptorsNervous system injuryPatch-clamp recordingsMouse subventricular zoneSVZ neurogenic nicheNeural progenitor responseAbsence of responseSystem injuryCerebral ventricleProgenitor responseLateral ventricleNeurogenic nichePurinergic receptorsClamp recordingsExtracellular adenosineReceptorsCellular damageWidespread expressionInflammation
2008
The astrocyte odyssey
Wang DD, Bordey A. The astrocyte odyssey. Progress In Neurobiology 2008, 86: 342-367. PMID: 18948166, PMCID: PMC2613184, DOI: 10.1016/j.pneurobio.2008.09.015.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdult neurogenic zonesFunction of astrocytesAstrocytic calcium wavesPopulation of astrocytesDifferent molecular identitiesNeural stem cellsGlutamate releaseNeurogenic zonesNeurogenic nicheNeuronal activityNervous systemStem cell characteristicsAstrocytesNeuronsCalcium wavesVivo roleSupport cellsStem cellsEqual numberCellsDiverse populationsMolecular identityCell characteristicsPioneer discoveriesCentral playerGFAP‐GFP neural progenitors are antigenically homogeneous and anchored in their enclosed mosaic niche
Platel J, Gordon V, Heintz T, Bordey A. GFAP‐GFP neural progenitors are antigenically homogeneous and anchored in their enclosed mosaic niche. Glia 2008, 57: 66-78. PMID: 18661547, DOI: 10.1002/glia.20735.Peer-Reviewed Original ResearchConceptsBrain lipid-binding proteinGFAP-expressing cellsSubventricular zoneEGF receptorNeurogenic subventricular zoneGFP-fluorescent cellsHuman GFAP promoterProliferative marker Ki67Neural stem cellsCell typesNeurogenic zonesNG2 cellsPostnatal neurogenesisAcute slicesNeurogenic nicheOlfactory bulbTransgenic miceDifferent cell populationsRostral extensionAntigenic markersGFAP promoterProgenitor markersNeural progenitorsCell populationsCellular mosaic